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ClinicalTrials.gov 9 recruiting now early-phase tilt small index

Post-Acute COVID-19 Syndrome: early-phase trial registry

9 of 15 indexed Post-Acute COVID-19 Syndrome trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 9 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Post-Acute COVID-19 Syndrome: 15 US clinical trials tracked, 9 recruiting.

Post-Acute COVID-19 Syndrome is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University Medical Center, running 2 of these trials.

Enrollment posture brief

Registry condition post-acute-covid-19-syndrome

OPEN 9 | RECR 60% | LATE 0 | EARLY 4 | RANK #1140 | SPON 2

Nearest open-share peer: Abuse, Drug (60% recruiting · 5 trials)

Post-Acute COVID-19 Synd (th…60%Advanced Lung Non-Small Cell53.3%AIDS26.7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Post-Acute COVID-19 Syndrome

Post-Acute COVID-19 Syndrome lists 9 open slots (60% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Post-Acute COVID-19 Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Post-Acute COVID-19 Syndrome is recruiting above its size-band peers.

    9 of 15 indexed trials (60%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Post-Acute COVID-19 Syndrome trials is spread across many organizations.

    Vanderbilt University Medical Center accounts for 2 of 15 trials (13.3%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Most Post-Acute COVID-19 Syndrome trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 15 trials that report a genuine target (sentinel values excluded). 9 of those (60%) plan for fewer than 100 participants.

  4. Post-Acute COVID-19 Syndrome research is mostly interventional.

    13 interventional and 2 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 24

Open and recent trials

15 total, page 1 of 1

RECRUITING 10,000 participants

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

Brain Inflammation Collaborative

NCT04806620

RECRUITING NA 400 participants

Long-Covid-19 Alleviation Through Learning Mindfulness Study

Columbia University

NCT07140094

RECRUITING NA 348 participants

Care for Veterans Post-COVID-19

VA Office of Research and Development

NCT05787379

RECRUITING Phase 2 150 participants

AT1001 for the Treatment of Long COVID

Massachusetts General Hospital

NCT05747534

RECRUITING NA 60 participants

Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome

Vanderbilt University Medical Center

NCT05421208

RECRUITING NA 56 participants

Dietary Intervention to Mitigate Post-Acute COVID-19 Syndrome

University of Maryland, Baltimore

NCT05977179

RECRUITING Phase 2 50 participants

Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS

Vanderbilt University Medical Center

NCT07189936

RECRUITING NA 40 participants

Brain-Training Treatment for Long COVID in Older Adults

UConn Health

NCT05705193

RECRUITING NA 30 participants

Long COVID Brain Fog: Cognitive Rehabilitation Trial

University of Alabama at Birmingham

NCT06095297

ACTIVE NOT RECRUITING NA 400 participants

A Study of Positive Emotions With Long COVID-19

University of California, Davis

NCT05676008

ACTIVE NOT RECRUITING Phase 2 180 participants

Probiotic Use for Recovery Enhancement From Long COVID-19

Rush University Medical Center

NCT06643299

ACTIVE NOT RECRUITING Phase 2 60 participants

Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction

University of North Carolina, Chapel Hill

NCT06204432

ACTIVE NOT RECRUITING NA 10 participants

HOBSCOTCH for People With Post Acute COVID-19 Syndrome (PACS)

Dartmouth-Hitchcock Medical Center

NCT06391489

ACTIVE NOT RECRUITING 1 participants

Use and Effectiveness of COVID-19 Vaccines Using State Vaccine Registries and Insurance Claims Data

Pfizer

NCT05876377

COMPLETED NA 30 participants

Humanity Neurotech Device Clinical Trial in Adults With Long COVID Cognitive Dysfunction

Icahn School of Medicine at Mount Sinai

NCT06739668

Phase Distribution

PhaseTrial count
Phase 2 4

Named interventions

Most-linked intervention names on Post-Acute COVID-19 Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Pascal device Device
1 trials
HOBSCOTCH-PACS Behavioral
1 trials
Pfizer-BioNTech COVID-19 mRNA vaccine Biological
1 trials
Olfactory Training Kit - "The Olfactory Kit, by AdvancedRx" Other
1 trials
Sodium Citrate Drug
1 trials
Probiotic Agent Drug
1 trials
Microdosing of mindfulness Behavioral
1 trials
To Measure Splanchnic venous capacitance after 28 days of Treatment with Placebo Diagnostic test
1 trials

US sites by state

Facility locations filed on Post-Acute COVID-19 Syndrome trials. A trial with sites in several states counts in each.

New York 3 trials
Tennessee 2 trials
Wisconsin 1 trials
New Jersey 1 trials
New Hampshire 1 trials
North Carolina 1 trials
Maryland 1 trials
Massachusetts 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Post-Acute COVID-19 Syndrome page

15 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Post-Acute COVID-19 Syndrome condition card totals 15 registered trials; most-linked intervention Pascal device; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.