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ClinicalTrials.gov 9 recruiting now official registry

Post-Acute COVID-19 Syndrome clinical trials

9 of 15 indexed Post-Acute COVID-19 Syndrome trials are currently recruiting.

15 US clinical trials · 9 currently recruiting

Post-Acute COVID-19 Syndrome is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University Medical Center, running 2 of these trials.

The research picture

Post-Acute COVID-19 Syndrome has 15 registered US clinical trials, 9 of them open to new participants right now, about 60% of the total.

9
recruiting participants now
60%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Vanderbilt University Medical Center
Phase 24

Active & Recent Trials

15 total, page 1 of 1

RECRUITING 10,000 participants

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

Brain Inflammation Collaborative

NCT04806620

RECRUITING NA 400 participants

Long-Covid-19 Alleviation Through Learning Mindfulness Study

Columbia University

NCT07140094

RECRUITING NA 348 participants

Care for Veterans Post-COVID-19

VA Office of Research and Development

NCT05787379

RECRUITING Phase 2 150 participants

AT1001 for the Treatment of Long COVID

Massachusetts General Hospital

NCT05747534

RECRUITING NA 60 participants

Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome

Vanderbilt University Medical Center

NCT05421208

RECRUITING NA 56 participants

Dietary Intervention to Mitigate Post-Acute COVID-19 Syndrome

University of Maryland, Baltimore

NCT05977179

RECRUITING Phase 2 50 participants

Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS

Vanderbilt University Medical Center

NCT07189936

RECRUITING NA 40 participants

Brain-Training Treatment for Long COVID in Older Adults

UConn Health

NCT05705193

RECRUITING NA 30 participants

Long COVID Brain Fog: Cognitive Rehabilitation Trial

University of Alabama at Birmingham

NCT06095297

ACTIVE NOT RECRUITING NA 400 participants

A Study of Positive Emotions With Long COVID-19

University of California, Davis

NCT05676008

ACTIVE NOT RECRUITING Phase 2 180 participants

Probiotic Use for Recovery Enhancement From Long COVID-19

Rush University Medical Center

NCT06643299

ACTIVE NOT RECRUITING Phase 2 60 participants

Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction

University of North Carolina, Chapel Hill

NCT06204432

ACTIVE NOT RECRUITING NA 10 participants

HOBSCOTCH for People With Post Acute COVID-19 Syndrome (PACS)

Dartmouth-Hitchcock Medical Center

NCT06391489

ACTIVE NOT RECRUITING 1 participants

Use and Effectiveness of COVID-19 Vaccines Using State Vaccine Registries and Insurance Claims Data

Pfizer

NCT05876377

COMPLETED NA 30 participants

Humanity Neurotech Device Clinical Trial in Adults With Long COVID Cognitive Dysfunction

Icahn School of Medicine at Mount Sinai

NCT06739668

Phase Distribution

PhaseTrial count
Phase 2 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Post-Acute COVID-19 Syndrome Trial Landscape

15 indexed Post-Acute COVID-19 Syndrome studies · 9 recruiting (60%).

Phase mix: 0 late (III/IV) vs 4 early (I/II).

Top sponsor: Vanderbilt University Medical Center (2 trials), 9 others listed. 15 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Post-Acute COVID-19 Syndrome?

PlainTrial tracks 15 US clinical trials for Post-Acute COVID-19 Syndrome, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Post-Acute COVID-19 Syndrome?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.