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NCT05977179 · ClinicalTrials.gov registry record · NA

Dietary Intervention to Mitigate Post-Acute COVID-19 Syndrome

A NA study of Fatigue and Post-Acute COVID-19 Syndrome, sponsored by University of Maryland, Baltimore.

Recruiting
Registry status
NA
Development phase
56
Enrollment target
1
Study location

NCT05977179: Recruiting NA study of Fatigue and Post-Acute COVID-19 Syndrome, sponsored by University of Maryland, Baltimore.

NCT05977179 is a NA study of Fatigue and Post-Acute COVID-19 Syndrome that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 56 participants, below the 218-participant average among 109 other Fatigue trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05977179, a NA study of Fatigue and Post-Acute COVID-19 Syndrome, is actively recruiting participants, sponsored by University of Maryland, Baltimore.

RECRUITING
Registry status
NA
Development phase
56 participants
Enrollment target
1
Study location

Study Summary

The primary objective of this study is to conduct a 16-week randomized controlled trial aimed at investigating the effectiveness of the Whole-Diet Approach when following a healthy US-style diet rich in anti-inflammatory properties. The study will focus on evaluating its impact on reducing symptoms related to Post-Acute Sequelae of SARS-CoV-2 Infection (PACS) in adults aged 50 years and older. The main research questions this study aims to answer are: 1. Does adhering to a healthy US-style diet, which is abundant in anti-inflammatory properties, effectively mitigate fatigue symptoms in adults with PACS? 2. Does adhering to a healthy US-style diet, which is abundant in anti-inflammatory properties, effectively mitigate declines in muscle function and physical performance in adults with PACS? At the beginning of the study, eligible participants will be randomly assigned to either the Dietary Intervention Group, where they will receive personalized dietary plans and weekly sessions, or the Attention Control Group, where they will attend general health sessions on a weekly basis as well. This research intends to shed light on the potential benefits of the Whole-Diet Approach and its role in ameliorating PACS-related symptoms among older adults. By comparing the outcomes of the two groups, we hope to gain valuable insights into the effectiveness of this dietary intervention in improving the quality of life for individuals dealing with PACS.

Primary Outcome

Fatigue will be assessed by the brief fatigue inventory (BFI)

Interventions

  • OTHER Attention Control
  • OTHER Dietary intervention to mitigate Post-Acute COVID-19 Syndrome

Study Locations (1)

Maryland

  • University of Maryland, Baltimore - Baltimore

Trial Details

FieldValue
Enrollment Target 56 participants
Start Date 2025-05-12
Est. Completion 2028-09-30
Phase NA
University of Maryland, Baltimore

560 total trials

What NCT05977179 shows while recruiting

NCT05977179 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 218-participant average among 109 other Fatigue trials with a reported enrollment target (74% lower).

The record links to 2 conditions, with Fatigue appearing as the primary indexed condition, and to 2 interventions - of which Attention Control is the first listed.

NCT05977179 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT05977179 about?

NCT05977179 is a clinical study titled "Dietary Intervention to Mitigate Post-Acute COVID-19 Syndrome". The primary objective of this study is to conduct a 16-week randomized controlled trial aimed at investigating the effectiveness of the Whole-Diet Approach when following a healthy US-style diet rich in anti-inflammatory properties. The study will focus on evaluating its impact on reducing symptoms ...

What is the current status of trial NCT05977179?

This trial is currently recruiting. It is a NA study. The enrollment target is 56 participants. The study started on 2025-05-12. Estimated completion is 2028-09-30.

What conditions does trial NCT05977179 study?

This clinical trial studies the following conditions: Fatigue, Post-Acute COVID-19 Syndrome.

What interventions are being tested in trial NCT05977179?

The interventions under investigation include: Attention Control (OTHER), Dietary intervention to mitigate Post-Acute COVID-19 Syndrome (OTHER).

Who is sponsoring clinical trial NCT05977179?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05977179 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Fatigue

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05977179's enrollment target sits among peer trials

56 59th of 109 higher than 51 of 109 other Fatigue trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Fatigue trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05977179, the US trial registry maintained by the National Library of Medicine. NCT05977179 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.