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Polycystic Ovary Syndrome: early-phase trial registry
13 of 31 indexed Polycystic Ovary Syndrome trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #495 of 28,707 conditions by registered trial count.
31 US clinical trials · 13 currently recruiting · #495 of 28,707 conditions by registered trial count
Polycystic Ovary Syndrome: 31 US clinical trials tracked, 13 recruiting.
Polycystic Ovary Syndrome is the subject of 31 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is University of Virginia, running 4 of these trials.
Enrollment posture brief
Registry condition polycystic-ovary-syndrome
OPEN 13 | RECR 42% | LATE 3 | EARLY 7 | RANK #495 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Degenerative Disc Disease (42% recruiting · 43 trials)
Polycystic Ovary Syndrome lists 13 open slots (42% of 31 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Polycystic Ovary Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Polycystic Ovary Syndrome is recruiting above its size-band peers.
13 of 31 indexed trials (41.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Polycystic Ovary Syndrome trials is spread across many organizations.
University of Virginia accounts for 4 of 31 trials (12.9%). 26 distinct sponsors appear on at least one study for this condition label.
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Most Polycystic Ovary Syndrome trials plan to enrol fewer than 100 people.
Median target enrolment is 70 among the 31 trials that report a genuine target (sentinel values excluded). 20 of those (64.5%) plan for fewer than 100 participants.
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Polycystic Ovary Syndrome research is mostly interventional.
26 interventional and 5 observational studies make up this index (83.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
31 total, page 1 of 1
Apple Women's Health Study
Apple
NCT04196595
The PCOS Challenge Study
PCOS Challenge: The National Polycystic Ovary Syndrome Association
NCT05797909
Fasting Insulin and HOMA-IR by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
Lilli Health
NCT05950282
IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer
Bruce Rose, MD
NCT04149496
The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System
May Health
NCT06206746
Myo-Inositol for Infertility in PCOS
University of Oklahoma
NCT04407754
Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOS
University of Virginia
NCT03905603
Combined Oral Contraceptive Pill and Resistance Starch
University of Pennsylvania
NCT06852365
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT03049462
Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients
West Virginia School of Osteopathic Medicine
NCT06049420
Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome
University of Virginia
NCT03401047
Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?
University of Virginia
NCT04723862
Hyperandrogenemia and Altered Day-night LH Pulse Patterns
University of Virginia
NCT03068910
Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With Anovulation
Rachel Mejia
NCT05206448
A Study to Evaluate the Effect of Elix Cycle Balance and Daily Harmony on Polycystic Ovary Syndrome
Zenchi
NCT05875233
PCOS & Insulin Resistance Exercise Study
University of California, San Francisco
NCT02303470
Adipose Tissue and Polycystic Ovary Syndrome (PCOS)(EIFFEL)
AdventHealth Translational Research Institute
NCT01745471
Restoring Metabolic and Reproductive Health With Sleep in PCOS Study, CPAP Trial
University of California, San Francisco
NCT05920694
Comparison of Lifestyle Markers Between Women With and Without Polycystic Ovary Syndrome
Cornell University
NCT01859663
Metabolic Syndrome in PCOS: Precursors and Interventions
Northwestern University
NCT00442689
Insulin and the Polycystic Ovary Syndrome--Weight Reduction Study
Virginia Commonwealth University
NCT00436865
Vitamin D Increases Serum Levels of the Soluble Receptor for Advanced Glycation End Products in Women With PCOS
Maimonides Medical Center
NCT03644212
Evaluation of Vitamin D in Women With PCOS and Sexual Dysfunction
Wright State University
NCT02865187
Mechanisms of Increased Androgen Production Among Women With Polycystic Ovary Syndrome
University of California, San Diego
NCT00989781
Effects of a Female Hormone Balance Supplement on Symptoms of Polycystic Ovary Syndrome and Severe Premenstrual Syndrome
Rael
NCT06124300
A Single Group Study to Evaluate the Effects of a Myo-Inositol and D-Chiro Inositol Supplement on Symptoms Associated With Polycystic Ovary Syndrome and Hormone Imbalance
Optify
NCT06158932
Ovarian Morphology and Theca Cell Androgen Production in Women With Polycystic Ovary Syndrome (PCOS)
University of California, San Diego
NCT02145247
Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis
Woman's
NCT02022007
A Trial of Lipitor (Atorvastatin) for the Treatment of Polycystic Ovary Syndrome (PCOS) in Women With Elevated Low-density Lipoprotein (LDL) Cholesterol
Milton S. Hershey Medical Center
NCT00529542
Metabolic Study of Women With Polycystic Ovary Syndrome and Sleep Apnea
University of Chicago
NCT00696111
Effects of Exercise for Overweight Women With Polycystic Ovary Syndrome
Pennington Biomedical Research Center
NCT01150539
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Polycystic Ovary Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Polycystic Ovary Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Polycystic Ovary Syndrome page
31 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 13 Polycystic Ovary Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Virginia sponsors the most Polycystic Ovary Syndrome trials on record, review their full trial history before evaluating a specific study. See University of Virginia's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Polycystic Ovary Syndrome condition card totals 31 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.