Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Polycystic Ovary Syndrome
Open-data reference.
31 US clinical trials · 13 currently recruiting
Active & Recent Trials
Apple Women's Health Study
Apple
NCT04196595
The PCOS Challenge Study
PCOS Challenge: The National Polycystic Ovary Syndrome Association
NCT05797909
Fasting Insulin and HOMA-IR by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
Lilli Health
NCT05950282
IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer
Bruce Rose, MD
NCT04149496
The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System
May Health
NCT06206746
Myo-Inositol for Infertility in PCOS
University of Oklahoma
NCT04407754
Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOS
University of Virginia
NCT03905603
Combined Oral Contraceptive Pill and Resistance Starch
University of Pennsylvania
NCT06852365
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT03049462
Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients
West Virginia School of Osteopathic Medicine
NCT06049420
Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome
University of Virginia
NCT03401047
Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?
University of Virginia
NCT04723862
Hyperandrogenemia and Altered Day-night LH Pulse Patterns
University of Virginia
NCT03068910
Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With Anovulation
Rachel Mejia
NCT05206448
A Study to Evaluate the Effect of Elix Cycle Balance and Daily Harmony on Polycystic Ovary Syndrome
Zenchi
NCT05875233
PCOS & Insulin Resistance Exercise Study
University of California, San Francis
NCT02303470
Adipose Tissue and Polycystic Ovary Syndrome (PCOS)(EIFFEL)
AdventHealth Translational Research Institute
NCT01745471
Restoring Metabolic and Reproductive Health With Sleep in PCOS Study, CPAP Trial
University of California, San Francis
NCT05920694
Comparison of Lifestyle Markers Between Women With and Without Polycystic Ovary Syndrome
Cornell University
NCT01859663
Metabolic Syndrome in PCOS: Precursors and Interventions
Northwestern University
NCT00442689
Insulin and the Polycystic Ovary Syndrome--Weight Reduction Study
Virginia Commonwealth University
NCT00436865
Vitamin D Increases Serum Levels of the Soluble Receptor for Advanced Glycation End Products in Women With PCOS
Maimonides Medical Center
NCT03644212
Evaluation of Vitamin D in Women With PCOS and Sexual Dysfunction
Wright State University
NCT02865187
Mechanisms of Increased Androgen Production Among Women With Polycystic Ovary Syndrome
University of California, San Diego
NCT00989781
Effects of a Female Hormone Balance Supplement on Symptoms of Polycystic Ovary Syndrome and Severe Premenstrual Syndrome
Rael
NCT06124300
A Single Group Study to Evaluate the Effects of a Myo-Inositol and D-Chiro Inositol Supplement on Symptoms Associated With Polycystic Ovary Syndrome and Hormone Imbalance
Optify
NCT06158932
Ovarian Morphology and Theca Cell Androgen Production in Women With Polycystic Ovary Syndrome (PCOS)
University of California, San Diego
NCT02145247
Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis
Woman's
NCT02022007
A Trial of Lipitor (Atorvastatin) for the Treatment of Polycystic Ovary Syndrome (PCOS) in Women With Elevated Low-density Lipoprotein (LDL) Cholesterol
Milton S. Hershey Medical Center
NCT00529542
Metabolic Study of Women With Polycystic Ovary Syndrome and Sleep Apnea
University of Chicago
NCT00696111
Effects of Exercise for Overweight Women With Polycystic Ovary Syndrome
Pennington Biomedical Research Center
NCT01150539
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 5 |
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Polycystic Ovary Syndrome Trial Landscape
ClinicalTrials.gov lists 31 US studies indexed under Polycystic Ovary Syndrome, and 13 of those are currently open to recruitment — roughly 42% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Polycystic Ovary Syndrome shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Polycystic Ovary Syndrome is led by University of Virginia with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 31 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Polycystic Ovary Syndrome?
PlainTrial tracks 31 US clinical trials for Polycystic Ovary Syndrome, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Polycystic Ovary Syndrome?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.