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NCT03905603 · ClinicalTrials.gov registry record · Early Phase 1

Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOS

A Early Phase 1 study of Polycystic Ovary Syndrome, sponsored by University of Virginia.

Recruiting
Registry status
Early Phase 1
Development phase
144
Enrollment target
1
Study location

NCT03905603 is a Early Phase 1 study of Polycystic Ovary Syndrome that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 144 participants, below the 17,253-participant average among 30 other Polycystic Ovary Syndrome trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03905603, a Early Phase 1 study of Polycystic Ovary Syndrome, is actively recruiting participants, sponsored by University of Virginia.

RECRUITING
Registry status
Early Phase 1
Development phase
144 participants
Enrollment target
1
Study location

Study Summary

The objective of the study is to determine the relative contributions of four established predictors of hyperandrogenism (luteinizing hormone \[LH\] secretion, ovarian response to recombinant human chorionic gonadotropin \[r-hCG\] administration, adrenal response to adrenocorticotropic hormone \[ACTH\] administration, and hyperinsulinemia) in older vs. young women with Polycystic Ovary Syndrome (PCOS) in a cross-sectional, physiological study. The investigators hypothesize that hyperinsulinemia is a stronger independent predictor of free testosterone (T) in older reproductive aged (vs. young) women with PCOS.

Conditions Studied

Interventions

  • DRUG ACTH
  • DRUG rhCG

Study Locations (1)

Virginia

  • University of Virginia - Charlottesville

Trial Details

FieldValue
Enrollment Target 144 participants
Start Date 2019-10-08
Est. Completion 2026-05-01
Phase Early Phase 1

Sponsor

University of Virginia

449 total trials

What the Registry Record Tells You About NCT03905603

The ClinicalTrials.gov registry entry for NCT03905603 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 144 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 17,253-participant average among 30 other Polycystic Ovary Syndrome trials with a reported enrollment target (99% lower). The listed sponsor is University of Virginia, which has 449 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Polycystic Ovary Syndrome appearing as the primary indexed condition, and to 2 interventions - of which ACTH is the first listed.

NCT03905603 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.

Frequently Asked Questions

What is clinical trial NCT03905603 about?

NCT03905603 is a clinical study titled "Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOS". The objective of the study is to determine the relative contributions of four established predictors of hyperandrogenism (luteinizing hormone \[LH\] secretion, ovarian response to recombinant human chorionic gonadotropin \[r-hCG\] administration, adrenal response to adrenocorticotropic hormone \[ACT...

What is the current status of trial NCT03905603?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 144 participants. The study started on 2019-10-08. Estimated completion is 2026-05-01.

What conditions does trial NCT03905603 study?

This clinical trial studies the following conditions: Polycystic Ovary Syndrome.

What interventions are being tested in trial NCT03905603?

The interventions under investigation include: ACTH (DRUG), rhCG (DRUG).

Who is sponsoring clinical trial NCT03905603?

This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03905603 being conducted?

This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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