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NCT04334343 · ClinicalTrials.gov registry record · NA
Investigating the Effects of Aerobic and Resistance Training in Vivo on Skeletal Muscle Metabolism in Vitro in Primary Human Muscle Cells (MoTrMyo)
A NA study of Physical Activity, sponsored by AdventHealth Translational Research Institute.
- Recruiting
- Registry status
- NA
- Development phase
- 400
- Enrollment target
- 1
- Study location
NCT04334343: Recruiting NA study of Physical Activity, sponsored by AdventHealth Translational Research Institute.
NCT04334343 is a NA study of Physical Activity that is actively recruiting participants, run by AdventHealth Translational Research Institute. The registered enrollment target is 400 participants, above the 355-participant average among 131 other Physical Activity trials with a reported enrollment target (13% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04334343, a NA study of Physical Activity, is actively recruiting participants, sponsored by AdventHealth Translational Research Institute.
- RECRUITING
- Registry status
- NA
- Development phase
- 400 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of the study is to examine the ability of resistance or aerobic exercise training to "imprint" skeletal muscle cells in a manner which confers long-term changes in this tissue which in-turn contribute to improved metabolic health and functional capacity through epigenetic regulation of novel exercise response genes. This study will also provide primary human skeletal muscle cells to the Molecular Transducers of Physical Activity Consortium (MoTrPAC) (NCT03960827) repository for future use.
Primary Outcome
Tested via a Analysis of Covariance (ANCOVA) with baseline as covariate followed by post-hoc multiple comparisons.
Conditions Studied
Interventions
- OTHER Additional Muscle Biopsy Collection
Study Locations (1)
Florida
- AdventHealth Translational Research Institute - Orlando
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2020-11-01 |
| Est. Completion | 2025-12 |
| Phase | NA |
What NCT04334343 shows while recruiting
NCT04334343 is an interventional study that assigns participants to a tested intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, above the 355-participant average among 131 other Physical Activity trials with a reported enrollment target (13% higher).
The record links to 1 condition, with Physical Activity appearing as the primary indexed condition, and to 1 intervention - of which Additional Muscle Biopsy Collection is the first listed.
NCT04334343 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT04334343 about?
NCT04334343 is a clinical study titled "Investigating the Effects of Aerobic and Resistance Training in Vivo on Skeletal Muscle Metabolism in Vitro in Primary Human Muscle Cells (MoTrMyo)". The goal of the study is to examine the ability of resistance or aerobic exercise training to "imprint" skeletal muscle cells in a manner which confers long-term changes in this tissue which in-turn contribute to improved metabolic health and functional capacity through epigenetic regulation of nove...
What is the current status of trial NCT04334343?
This trial is currently recruiting. It is a NA study. The enrollment target is 400 participants. The study started on 2020-11-01. Estimated completion is 2025-12.
What conditions does trial NCT04334343 study?
This clinical trial studies the following conditions: Physical Activity.
What interventions are being tested in trial NCT04334343?
The interventions under investigation include: Additional Muscle Biopsy Collection (OTHER).
Who is sponsoring clinical trial NCT04334343?
This trial is sponsored by AdventHealth Translational Research Institute, which has 54 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04334343 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Physical Activity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04334343's enrollment target sits among peer trials
400 26th of 131 higher than 104 of 131 other Physical Activity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Physical Activity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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