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Peripheral Arterial Disease: early-phase trial registry
35 of 80 indexed Peripheral Arterial Disease trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #173 of 28,707 conditions by registered trial count.
80 US clinical trials · 35 currently recruiting · #173 of 28,707 conditions by registered trial count
Peripheral Arterial Disease: 80 US clinical trials tracked, 35 recruiting.
Peripheral Arterial Disease is the subject of 80 registered US clinical trials on ClinicalTrials.gov, 35 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most active sponsor is University of Nebraska, running 7 of these trials.
Enrollment posture brief
Registry condition peripheral-arterial-disease
OPEN 35 | RECR 44% | LATE 7 | EARLY 14 | RANK #173 | SPON 7
Volume-matched condition peers
Nearest open-share peer: Acute Respiratory Distress Syndrome (44% recruiting · 32 trials)
Peripheral Arterial Disease lists 35 open slots (44% of 80 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Peripheral Arterial Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Peripheral Arterial Disease is recruiting above its size-band peers.
35 of 80 indexed trials (43.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Peripheral Arterial Disease trials is spread across many organizations.
University of Nebraska accounts for 7 of 80 trials (8.8%). 56 distinct sponsors appear on at least one study for this condition label.
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Typical Peripheral Arterial Disease enrolment sits around 100 participants.
Median target enrolment is 100 among the 80 trials that report a genuine target (sentinel values excluded). 40 of those (50%) plan for fewer than 100 participants.
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Peripheral Arterial Disease research is mostly interventional.
62 interventional and 18 observational studies make up this index (77.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
80 total, page 1 of 2
A Real-World Registry of Chronic Wounds and Ulcers
U.S. Wound Registry
NCT02280733
Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes
Baylor Research Institute
NCT01904851
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk
Population Health Research Institute
NCT04774159
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
Eli Lilly and Company
NCT07223593
Advanta VXT and Flixene PMCF Registry
Atrium Medical Corporation
NCT07161583
Pounce™ Thrombectomy System Retrospective Registry
SurModics
NCT05868161
The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry)
Endologix
NCT06315023
Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease
Mayo Clinic
NCT06952543
SELUTION4BTK Trial
M.A. Med Alliance S.A.
NCT05055297
Intravascular Ultrasound Imaging Guidance for Optimal Revascularization of Limb Arteries
Baylor Research Institute
NCT07353905
Vascular Trial Associated Registry Pilot
Corewell Health West
NCT07076082
Prehabilitation and Rehabilitation in PAD
Palo Alto Veterans Institute for Research
NCT06566976
The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease
W.L.Gore & Associates
NCT05811364
SMART Exercise for PAD
Northwestern University
NCT06032065
The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)
Avantec Vascular
NCT06321575
Using SnapshotNIR With Provocative Leg Maneuver for PAD Assessment
Kent Imaging
NCT06237621
Effects of Carnosine In Patients With Peripheral Arterial Disease Patients
Shahid Baba
NCT06480760
Randomized Clinical Trial for Ewing Amputation in the VA
VA Office of Research and Development
NCT05437562
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
LimFlow
NCT05313165
Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis
University of Nebraska
NCT02842424
Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status
University of Virginia
NCT06009276
Passive Stretching in Peripheral Arterial Disease Patients
University of Wisconsin, La Crosse
NCT06420752
MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology
University of Nebraska
NCT06409949
Assessment of the Utility of the Pantheris Small Vessel (SV) System
Avinger
NCT04793581
CRUSH PAD: Real-world Outcomes Following Use of Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions
Yale University
NCT05145478
The ROAMM-EHR Study
University of Florida
NCT06263322
Fuzzy Wale Compression Stockinet to Promote Healing Following Transtibial Amputation for Peripheral Arterial Disease
Mayo Clinic
NCT06308562
Fisetin to Reduce Senescence and Mobility Impairment in PAD
Northwestern University
NCT06399809
Augmentation of Limb Perfusion With Contrast Ultrasound
Oregon Health and Science University
NCT03195556
Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention
University Hospitals Cleveland Medical Center
NCT06544135
Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease
University of Nebraska
NCT06389149
Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease
University of Nebraska
NCT06319339
Carnosine for Peripheral Arterial Disease Patients
Shahid Baba
NCT05371145
SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease
University of Nebraska
NCT06480786
Replexa+ Shortwave Diathermy Device for Patients Diagnosed With Peripheral Artery Disease and Peripheral Neuropathy
Indiana University
NCT07336381
SCOPE-CLI: Shifting Care and Outcomes for Patients With Endangered Limbs
Yale University
NCT04710563
SELUTION4SFA Trial
M.A. Med Alliance S.A.
NCT05132361
TORUS 2 IDE Clinical Study
Endologix
NCT04130737
A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the Knee (STAND)
Micro Medical Solution
NCT03477604
The Impact of Factor Xa Inhibition on Thrombosis, Platelet Activation, and Endothelial Function in Peripheral Artery Disease
Vanderbilt University Medical Center
NCT05009862
BGC101 (EnEPC) Autologous Cell Therapy From Patient's Own Blood for Treatment of Critical Limb Ischemia (CLI)
BioGenCell
NCT02805023
BRAVO: Biomarker Risk Assessment in Vulnerable Outpatients
Northwestern University
NCT02276781
Pivotal Trial of a Novel Paclitaxel-Coated Percutaneous Angioplasty Balloon
Spectranetics Corporation
NCT01858428
Effectiveness of Medical Therapy, Endovascular Therapy, and Surgery for Peripheral Arterial Disease
Kaiser Permanente
NCT01588067
Evaluation of the GORE TIGRIS Vascular Stent
W.L.Gore & Associates
NCT01576055
The Role of microRNA-210 in Regulating Oxidative Stress in Patients With PAD
University of West Florida
NCT04089943
Mechanisms That Produce the Leg Dysfunction of Claudication & Treatment Strategies
University of Nebraska
NCT01970332
The Impact of Diabetes on REvascularization
Vanderbilt University Medical Center
NCT03085524
Treadmill Exercise and GM-CSF Study to Improving Functioning in Peripheral Artery Disease (PAD)
Northwestern University
NCT01408901
Edoxaban in Peripheral Arterial Disease
Daiichi Sankyo
NCT01802775
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 9 |
| Phase 2 | 5 |
| Phase 3 | 3 |
| Phase 4 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Peripheral Arterial Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Peripheral Arterial Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Peripheral Arterial Disease page
80 registered trials, 35 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 35 Peripheral Arterial Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Nebraska sponsors the most Peripheral Arterial Disease trials on record, review their full trial history before evaluating a specific study. See University of Nebraska's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Peripheral Arterial Disease condition card totals 80 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.