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Peripheral Arterial Disease clinical trials
35 of 80 indexed Peripheral Arterial Disease trials are currently recruiting.
80 US clinical trials · 35 currently recruiting
Peripheral Arterial Disease is the subject of 80 registered US clinical trials on ClinicalTrials.gov, 35 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most active sponsor is University of Nebraska, running 7 of these trials.
The research picture
Peripheral Arterial Disease has 80 registered US clinical trials, 35 of them open to new participants right now, about 44% of the total.
- 35
- recruiting participants now
- 44%
- of trials open to enrollment
- 7
- in Phase 3–4 (later-stage)
- 7
- top sponsor: University of Nebraska
Active & Recent Trials
80 total, page 2 of 2
Motivational Interviewing (MI) for African Americans With Peripheral Arterial Disease (PAD)
University of Kansas Medical Center
NCT01321086
Validation of a Novel Oscillometric-Based Algorithm for Determination of the Ankle-Brachial Index
Summit Doppler Systems
NCT01165437
A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascular Lesions Located in the infrapoplitEal Arteries beLow the Knee (DEEPER REVEAL)
ReFlow Medical
NCT05358353
Implementation of Telemedicine for Patient With Lower Extremity Wounds
University of California, Davis
NCT04440839
The OPC for Optimal Delivery of Paclitaxel for the Prevention of Endovascular Restenosis - Above and Below the Knee
Horizons International Peripheral Group
NCT02464501
EverFlex Post Approval Study
Medtronic Endovascular
NCT01680835
A Prospective, Multicenter Atherectomy Study Showing Luminal Gain in Subjects With Peripheral Vascular Blockages
Ra Medical Systems
NCT04241224
Distributed Registry
Stanford University
NCT03898570
Use of Ixmyelocel-T (Formerly Vascular Repair Cells [VRC]) in Patients With Peripheral Arterial Disease to Treat Critical Limb Ischemia
Vericel Corporation
NCT00468000
TurboPower + DCB Treatment of Femoropopliteal De Novo/ Restenotic and In-Stent Restenosis Lesions
Spectranetics Corporation
NCT03306199
A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation
Indiana University
NCT02685098
Pilot Study to Determine the Optimal Technique for Measurement of Ankle Blood Pressures
Summit Doppler Systems
NCT00819598
The Jetstream G3™ Calcium Study
Boston Scientific Corporation
NCT01273623
VasoStat vs. TR Band for Radial Hemostasis
Forge Medical
NCT04163471
Nitrites, Exercise, and Peripheral Arterial Disease
Duke University
NCT01684930
Local Paclitaxel Delivery for SFA Disease
University of Oklahoma
NCT00821028
Ischemic Preconditioning Claudication Study
Medical College of Wisconsin
NCT03511157
Dexamethasone Infusion to the Adventitia to Enhance Clinical Efficacy After Femoropopliteal Revascularization
University of California, San Francisco
NCT01507558
Cardiac Rehabilitation Program in Peripheral Arterial Disease
University of Kansas Medical Center
NCT03251391
ALD-301 for Critical Limb Ischemia, Randomized Trial
Aldagen
NCT00392509
Endothelial Function in Lower Extremity Bypass Grafts
Brigham and Women's Hospital
NCT00759707
Exercise and Weight Loss in PAD
VA Office of Research and Development
NCT02607033
Study of Human Placenta-derived Cells (PDA002) to Evaluate the Safety and Effectiveness in Subjects With PAD and DFU
Celularity Incorporated
NCT01859117
Drug Eluting Stent for the Management of PERipheral Arterial Disease Of the SFA (DESPERADO-SFA Study)
Arkansas Heart Hospital
NCT02734836
Feasibility Study to Evaluate Therapeutic Ultrasound (TUS) to Acutely Increase the Perfusion in Peripheral Arterial Disease (PAD)
Vibrato Medical
NCT05888740
Dietary Nitrate Supplementation and Thermoregulation
University of Nebraska
NCT03506646
Safety and Preliminary Efficacy of Adipose Derived Stem Cells and Low Frequency Ultrasound in PAD
Arkansas Heart Hospital
NCT02756884
Natural Vascular Scaffold (NVS) Therapy for Treatment of Atherosclerotic Lesions (Activate I)
Alucent Biomedical
NCT04188262
The Use of Fish Oil to Reduce Inflammation Caused by a Peripheral Vascular Intervention
University of California, San Francisco
NCT02096757
BOLD MRI as a Surrogate of Improved Muscle Oxygenation Following Endovascular Therapy for the Treatment of CLI
Zimmer Biomet
NCT02601430
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 9 |
| Phase 2 | 5 |
| Phase 3 | 3 |
| Phase 4 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Peripheral Arterial Disease Trial Landscape
80 indexed Peripheral Arterial Disease studies · 35 recruiting (44%).
Phase mix: 7 late (III/IV) vs 14 early (I/II).
Top sponsor: University of Nebraska (7 trials), 9 others listed. 30 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Peripheral Arterial Disease?
PlainTrial tracks 80 US clinical trials for Peripheral Arterial Disease, of which 35 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Peripheral Arterial Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.