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NCT03195556 · ClinicalTrials.gov registry record · NA

Augmentation of Limb Perfusion With Contrast Ultrasound

A NA study of Peripheral Arterial Disease, sponsored by Oregon Health and Science University.

Recruiting
Registry status
NA
Development phase
30
Enrollment target
1
Study location

NCT03195556 is a NA study of Peripheral Arterial Disease that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 30 participants, below the 4,206-participant average among 79 other Peripheral Arterial Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03195556, a NA study of Peripheral Arterial Disease, is actively recruiting participants, sponsored by Oregon Health and Science University.

RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

Our laboratory has discovered that ultrasound (US) imaging together with clinically approved microbubble ultrasound contrast agents can augment limb tissue perfusion. These observations have been made in mice with and without peripheral artery disease (PAD), and also in humans where high power contrast enhanced ultrasound (CEU) was used to measure perfusion but was found also to augment perfusion by almost 2-fold. The latter human studies were performed with ultrasound protocols designed for perfusion imaging and not for flow augmentation. In this study, we will measure the degree to which limb perfusion is augmented with specific therapeutic CEU settings that are still within the FDA-approved limits with regards to US power and contrast dosing.

Interventions

  • DEVICE Ultrasound

Study Locations (1)

Oregon

  • OHSU - Portland

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2018-06-18
Est. Completion 2019-12
Phase NA

What the Registry Record Tells You About NCT03195556

The ClinicalTrials.gov registry entry for NCT03195556 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,206-participant average among 79 other Peripheral Arterial Disease trials with a reported enrollment target (99% lower). The listed sponsor is Oregon Health and Science University, which has 546 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Peripheral Arterial Disease appearing as the primary indexed condition, and to 1 intervention - of which Ultrasound is the first listed.

NCT03195556 reports 1 study location spanning 1 distinct geographic area - top geographies include Oregon.

Frequently Asked Questions

What is clinical trial NCT03195556 about?

NCT03195556 is a clinical study titled "Augmentation of Limb Perfusion With Contrast Ultrasound". Our laboratory has discovered that ultrasound (US) imaging together with clinically approved microbubble ultrasound contrast agents can augment limb tissue perfusion. These observations have been made in mice with and without peripheral artery disease (PAD), and also in humans where high power contr...

What is the current status of trial NCT03195556?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2018-06-18. Estimated completion is 2019-12.

What conditions does trial NCT03195556 study?

This clinical trial studies the following conditions: Peripheral Arterial Disease.

What interventions are being tested in trial NCT03195556?

The interventions under investigation include: Ultrasound (DEVICE).

Who is sponsoring clinical trial NCT03195556?

This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03195556 being conducted?

This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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