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ClinicalTrials.gov 12 recruiting now official registry

Pancreatic Neoplasms clinical trials

Every US clinical trial registered for Pancreatic Neoplasms — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

32 US clinical trials · 12 currently recruiting

The research picture

Pancreatic Neoplasms has 32 registered US clinical trials, 12 of them open to new participants right now — about 38% of the total.

12
recruiting participants now
38%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
3
top sponsor: Nuvance Health

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 5,000 participants

Diagnostic Strategies, Risk Assessment and Progression of Pancreatic Cysts

Johns Hopkins University

NCT04473794

RECRUITING 4,000 participants

UCSF PANC Cyst Registry

University of California, San Francis

NCT04291651

RECRUITING 2,000 participants

Pancreatic Cancer Detection Consortium

City of Hope Medical Center

NCT06388967

RECRUITING 1,000 participants

Determining Individualized Cancer Therapy in Pancreatic Cancer

Medical College of Wisconsin

NCT05914987

RECRUITING 1,000 participants

Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

National Cancer Institute (NCI)

NCT01950572

RECRUITING 1,000 participants

ExoLuminate Study for Early Detection of Pancreatic Cancer

Biological Dynamics

NCT05625529

RECRUITING 800 participants

A Pancreatic Cancer Screening Study in Individuals With New-Onset or Deteriorating Diabetes Mellitus

Nuvance Health

NCT03937453

RECRUITING Phase 1 540 participants

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Eli Lilly and Company

NCT04956640

RECRUITING 200 participants

The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic Cancer

Nuvance Health

NCT04406831

RECRUITING 200 participants

A Pancreatic Cancer Screening Study in Hereditary High Risk Individuals

Nuvance Health

NCT03250078

RECRUITING Phase 1 100 participants

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

National Cancer Institute (NCI)

NCT06885697

RECRUITING Phase 2 45 participants

Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

UNC Lineberger Comprehensive Cancer Center

NCT03977233

ACTIVE NOT RECRUITING 500 participants

Lipidomics, Proteomics, Micro RNAs and Volatile Organic Compounds (VOC)

AdventHealth

NCT02531607

ACTIVE NOT RECRUITING Phase 1 160 participants

A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression

A2 Biotherapeutics

NCT05736731

ACTIVE NOT RECRUITING Phase 1 41 participants

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

Seagen, a wholly owned subsidiary of Pfizer

NCT05571839

ACTIVE NOT RECRUITING 18 participants

Hepatic Resection for Metastatic Pancreatic Cancer

Duke University

NCT02892305

ACTIVE NOT RECRUITING Phase 1 7 participants

A Study of Armed, Activated T-Cells in Patients With Advanced Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT04137536

COMPLETED Phase 3 866 participants

Nab-paclitaxel and Gemcitabine vs Gemcitabine Alone as Adjuvant Therapy for Patients With Resected Pancreatic Cancer (the "Apact" Study)

Celgene

NCT01964430

COMPLETED 175 participants

Chromogranin A as Blood Marker in Cancer Patients

Brahms

NCT03817866

COMPLETED Phase 1 65 participants

Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer

National Cancer Institute (NCI)

NCT02311361

COMPLETED Phase 1 48 participants

CO07204-Phase I/II of Oxaliplatin, Capecitabine & Sorafenib for Advanced Pancreatic & Biliary Carcinoma

University of Wisconsin, Madison

NCT00634751

COMPLETED Phase 1 47 participants

Study of Safety and Efficacy of Glufosfamide in Combination With Gemcitabine in Cancer

Threshold Pharmaceuticals

NCT00102752

COMPLETED 40 participants

Clinical Registry of nCLE in Masses and Cystic Tumors of the Pancreas, Lymph Nodes, Submucosal Lesions of the GI Tract

Mauna Kea Technologies

NCT01770405

COMPLETED Phase 1 38 participants

Etanercept and Gemcitabine in Patients With Advanced, Chemotherapy Naive Pancreatic Adenocarcinoma

Ohio State University Comprehensive Cancer Center

NCT00201838

COMPLETED NA 36 participants

Respiratory-gated Stereotactic Body Radiation Therapy for Adenocarcinoma of the Pancreas or Periampullary Region

Indiana University

NCT02780648

COMPLETED NA 28 participants

Trial Comparing EUS-guided Radiofrequency Ablation vs. EUS-guided Celiac Plexus Neurolysis

AdventHealth

NCT03152487

COMPLETED Phase 1 25 participants

Safety Study of Combination Chemotherapy in Patients With Metastatic Solid Tumors or Adenocarcinoma of the Pancreas

St. Luke's-Roosevelt Hospital Center

NCT00220649

COMPLETED NA 23 participants

Multidimensional Prehabilitation in Pancreatic Surgery for Pancreatic and Periampullary Neoplasms

Case Comprehensive Cancer Center

NCT05225038

COMPLETED Phase 1 15 participants

Nab-paclitaxel (Abraxane), Gemcitabine, and Capecitabine (Xeloda) for Pancreatic Adenocarcinoma

University of California, San Francis

NCT01161186

COMPLETED 15 participants

Feasibility of Using Ultrasound to Track Respiration Motion

Medical College of Wisconsin

NCT02173353

COMPLETED Phase 1 15 participants

FOLFIRINOX Plus IPI-926 for Advanced Pancreatic Adenocarcinoma

Andrew Ko

NCT01383538

COMPLETED Phase 3

A Phase 3 Trial of ALIMTA (LY231514, Pemetrexed) Plus GEMZAR Versus GEMZAR in Patients With Unresectable or Metastatic Cancer of the Pancreas.

Eli Lilly and Company

NCT00035035

Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 1
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pancreatic Neoplasms Trial Landscape

ClinicalTrials.gov lists 32 US studies indexed under Pancreatic Neoplasms, and 12 of those are currently open to recruitment — roughly 38% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Pancreatic Neoplasms shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Pancreatic Neoplasms is led by Nuvance Health with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 32 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pancreatic Neoplasms?

PlainTrial tracks 32 US clinical trials for Pancreatic Neoplasms, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pancreatic Neoplasms?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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