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ClinicalTrials.gov 12 recruiting now early-phase tilt

Pancreatic Neoplasms: early-phase trial registry

12 of 32 indexed Pancreatic Neoplasms trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #477 of 28,707 conditions by registered trial count.

32 US clinical trials · 12 currently recruiting · #477 of 28,707 conditions by registered trial count

Pancreatic Neoplasms: 32 US clinical trials tracked, 12 recruiting.

Pancreatic Neoplasms is the subject of 32 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is Nuvance Health, running 3 of these trials.

Enrollment posture brief

Registry condition pancreatic-neoplasms

OPEN 12 | RECR 38% | LATE 2 | EARLY 13 | RANK #477 | SPON 3

Nearest open-share peer: Acute-graft-versus-host Disease (38% recruiting · 8 trials)

Acute Respiratory Distress S43.8%Pancreatic Neoplasms (this)38%Cardiac Arrest37.5%Astigmatism28.1%Cardiovascular Risk Factor21.9%
Open-enrollment share among volume-matched conditions near Pancreatic Neoplasms

Pancreatic Neoplasms lists 12 open slots (38% of 32 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Pancreatic Neoplasms on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Pancreatic Neoplasms is recruiting below its size-band peers.

    12 of 32 indexed trials (37.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Pancreatic Neoplasms trials is spread across many organizations.

    Nuvance Health accounts for 3 of 32 trials (9.4%). 24 distinct sponsors appear on at least one study for this condition label.

  3. Typical Pancreatic Neoplasms enrolment sits around 65 participants.

    Median target enrolment is 65 among the 31 trials that report a genuine target (sentinel values excluded). 16 of those (51.6%) plan for fewer than 100 participants.

  4. Pancreatic Neoplasms splits between interventional and observational designs.

    18 interventional and 14 observational studies make up this index (56.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 112Phase 21Phase 32

Open and recent trials

32 total, page 1 of 1

RECRUITING 5,000 participants

Diagnostic Strategies, Risk Assessment and Progression of Pancreatic Cysts

Johns Hopkins University

NCT04473794

RECRUITING 4,000 participants

UCSF PANC Cyst Registry

University of California, San Francisco

NCT04291651

RECRUITING 2,000 participants

Pancreatic Cancer Detection Consortium

City of Hope Medical Center

NCT06388967

RECRUITING 1,000 participants

Determining Individualized Cancer Therapy in Pancreatic Cancer

Medical College of Wisconsin

NCT05914987

RECRUITING 1,000 participants

Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

National Cancer Institute (NCI)

NCT01950572

RECRUITING 1,000 participants

ExoLuminate Study for Early Detection of Pancreatic Cancer

Biological Dynamics

NCT05625529

RECRUITING 800 participants

A Pancreatic Cancer Screening Study in Individuals With New-Onset or Deteriorating Diabetes Mellitus

Nuvance Health

NCT03937453

RECRUITING Phase 1 540 participants

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Eli Lilly and Company

NCT04956640

RECRUITING 200 participants

The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic Cancer

Nuvance Health

NCT04406831

RECRUITING 200 participants

A Pancreatic Cancer Screening Study in Hereditary High Risk Individuals

Nuvance Health

NCT03250078

RECRUITING Phase 1 100 participants

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

National Cancer Institute (NCI)

NCT06885697

RECRUITING Phase 2 45 participants

Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

UNC Lineberger Comprehensive Cancer Center

NCT03977233

ACTIVE NOT RECRUITING 500 participants

Lipidomics, Proteomics, Micro RNAs and Volatile Organic Compounds (VOC)

AdventHealth

NCT02531607

ACTIVE NOT RECRUITING Phase 1 160 participants

A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression

A2 Biotherapeutics

NCT05736731

ACTIVE NOT RECRUITING Phase 1 41 participants

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

Seagen, a wholly owned subsidiary of Pfizer

NCT05571839

ACTIVE NOT RECRUITING 18 participants

Hepatic Resection for Metastatic Pancreatic Cancer

Duke University

NCT02892305

ACTIVE NOT RECRUITING Phase 1 7 participants

A Study of Armed, Activated T-Cells in Patients With Advanced Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT04137536

COMPLETED Phase 3 866 participants

Nab-paclitaxel and Gemcitabine vs Gemcitabine Alone as Adjuvant Therapy for Patients With Resected Pancreatic Cancer (the "Apact" Study)

Celgene

NCT01964430

COMPLETED 175 participants

Chromogranin A as Blood Marker in Cancer Patients

Brahms

NCT03817866

COMPLETED Phase 1 65 participants

Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer

National Cancer Institute (NCI)

NCT02311361

COMPLETED Phase 1 48 participants

CO07204-Phase I/II of Oxaliplatin, Capecitabine & Sorafenib for Advanced Pancreatic & Biliary Carcinoma

University of Wisconsin, Madison

NCT00634751

COMPLETED Phase 1 47 participants

Study of Safety and Efficacy of Glufosfamide in Combination With Gemcitabine in Cancer

Threshold Pharmaceuticals

NCT00102752

COMPLETED 40 participants

Clinical Registry of nCLE in Masses and Cystic Tumors of the Pancreas, Lymph Nodes, Submucosal Lesions of the GI Tract

Mauna Kea Technologies

NCT01770405

COMPLETED Phase 1 38 participants

Etanercept and Gemcitabine in Patients With Advanced, Chemotherapy Naive Pancreatic Adenocarcinoma

Ohio State University Comprehensive Cancer Center

NCT00201838

COMPLETED NA 36 participants

Respiratory-gated Stereotactic Body Radiation Therapy for Adenocarcinoma of the Pancreas or Periampullary Region

Indiana University

NCT02780648

COMPLETED NA 28 participants

Trial Comparing EUS-guided Radiofrequency Ablation vs. EUS-guided Celiac Plexus Neurolysis

AdventHealth

NCT03152487

COMPLETED Phase 1 25 participants

Safety Study of Combination Chemotherapy in Patients With Metastatic Solid Tumors or Adenocarcinoma of the Pancreas

St. Luke's-Roosevelt Hospital Center

NCT00220649

COMPLETED NA 23 participants

Multidimensional Prehabilitation in Pancreatic Surgery for Pancreatic and Periampullary Neoplasms

Case Comprehensive Cancer Center

NCT05225038

COMPLETED Phase 1 15 participants

Nab-paclitaxel (Abraxane), Gemcitabine, and Capecitabine (Xeloda) for Pancreatic Adenocarcinoma

University of California, San Francisco

NCT01161186

COMPLETED 15 participants

Feasibility of Using Ultrasound to Track Respiration Motion

Medical College of Wisconsin

NCT02173353

COMPLETED Phase 1 15 participants

FOLFIRINOX Plus IPI-926 for Advanced Pancreatic Adenocarcinoma

Andrew Ko

NCT01383538

COMPLETED Phase 3

A Phase 3 Trial of ALIMTA (LY231514, Pemetrexed) Plus GEMZAR Versus GEMZAR in Patients With Unresectable or Metastatic Cancer of the Pancreas.

Eli Lilly and Company

NCT00035035

Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 1
Phase 3 2

Named interventions

Most-linked intervention names on Pancreatic Neoplasms records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Gemcitabine Drug
3 trials
MRI/MRCP Diagnostic test
2 trials
Oxaliplatin Drug
2 trials
Sterostatic body radiation therapy (SBRT) Radiation
1 trials
Folfirinox, IPI-926 Drug
1 trials
Behavioral Medicine Behavioral
1 trials
Nutritional Dietary supplement
1 trials
GEMZAR Drug
1 trials

US sites by state

Facility locations filed on Pancreatic Neoplasms trials. A trial with sites in several states counts in each.

California 11 trials
New York 6 trials
Florida 6 trials
Connecticut 6 trials
Wisconsin 5 trials
Maryland 4 trials
Indiana 4 trials
Illinois 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Pancreatic Neoplasms page

32 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 12 Pancreatic Neoplasms trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Nuvance Health sponsors the most Pancreatic Neoplasms trials on record, review their full trial history before evaluating a specific study. See Nuvance Health's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pancreatic Neoplasms condition card totals 32 registered trials; most-linked intervention Gemcitabine; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.