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NCT02780648 · ClinicalTrials.gov registry record · NA

Respiratory-gated Stereotactic Body Radiation Therapy for Adenocarcinoma of the Pancreas or Periampullary Region

A NA study of Pancreatic Neoplasms, sponsored by Indiana University.

Completed
Registry status
NA
Development phase
36
Enrollment target
2
Study locations

NCT02780648 is a NA study of Pancreatic Neoplasms that has completed, run by Indiana University. The registered enrollment target is 36 participants, below the 600-participant average among 30 other Pancreatic Neoplasms trials with a reported enrollment target (94% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT02780648, a NA study of Pancreatic Neoplasms, has completed, sponsored by Indiana University.

COMPLETED
Registry status
NA
Development phase
36 participants
Enrollment target
2
Study locations

Study Summary

This is a single center, single arm unblinded prospective study of the safety of pancreatic stereotactic body radiation therapy (SBRT) in patients with unresectable, borderline resectable, or recurrent pancreatic/periampullary cancers who have previously undergone treatment with chemotherapy, surgery, photodynamic therapy, conventionally fractionated radiation treatment, or any combination of these therapies. Primary Objective • To estimate rates of acute (within 3 months of treatment) grade 3 or greater gastrointestinal and hematologic toxicity in patients treated with Linac-based SBRT for pancreatic or periampullary cancers who have previously received other treatment. Secondary Objectives * To estimate rates of late (\> 3 months after treatment) grade 2 gastritis, enteritis, fistula, and ulcer, or any other grade 3 or greater gastrointestinal toxicity in patients treated with Linac-based SBRT for pancreatic or periampullary cancers * To estimate rates of local progression, overall survival, metastasis-free survival, and progression-free survival in patients with pancreatic or periampullary cancers treated with fractionated Linac-based SBRT. * To evaluate the ability of Linac-based SBRT to provide pain control in patients with pain related to a pancreatic or periampullary tumor. * To evaluate quality of life in patients undergoing treatment with Linac-based SBRT for pancreatic or periampullary cancers.

Conditions Studied

Interventions

  • RADIATION Stereotactic Body Radiation

Study Locations (2)

Indiana

  • Indiana University Health Hospital - Indianapolis
  • Indiana University Health Melvin and Bren Simon Cancer Center - Indianapolis

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2016-05-01
Est. Completion 2025-05-15
Phase NA

Sponsor

Indiana University

890 total trials

What the Registry Record Tells You About NCT02780648

The ClinicalTrials.gov registry entry for NCT02780648 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 600-participant average among 30 other Pancreatic Neoplasms trials with a reported enrollment target (94% lower). The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pancreatic Neoplasms appearing as the primary indexed condition, and to 1 intervention - of which Stereotactic Body Radiation is the first listed.

NCT02780648 reports 2 study locations spanning 1 distinct geographic area - top geographies include Indiana.

Frequently Asked Questions

What is clinical trial NCT02780648 about?

NCT02780648 is a clinical study titled "Respiratory-gated Stereotactic Body Radiation Therapy for Adenocarcinoma of the Pancreas or Periampullary Region". This is a single center, single arm unblinded prospective study of the safety of pancreatic stereotactic body radiation therapy (SBRT) in patients with unresectable, borderline resectable, or recurrent pancreatic/periampullary cancers who have previously undergone treatment with chemotherapy, surger...

What is the current status of trial NCT02780648?

This trial is currently completed. It is a NA study. The enrollment target is 36 participants. The study started on 2016-05-01. Estimated completion is 2025-05-15.

What conditions does trial NCT02780648 study?

This clinical trial studies the following conditions: Pancreatic Neoplasms.

What interventions are being tested in trial NCT02780648?

The interventions under investigation include: Stereotactic Body Radiation (RADIATION).

Who is sponsoring clinical trial NCT02780648?

This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02780648 being conducted?

This trial has 2 study locations across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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