Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Myotonic Dystrophy: early-phase trial registry
7 of 10 indexed Myotonic Dystrophy trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,724 of 28,707 conditions by registered trial count.
10 US clinical trials · 7 currently recruiting · #1,724 of 28,707 conditions by registered trial count
Myotonic Dystrophy: 10 US clinical trials tracked, 7 recruiting.
Myotonic Dystrophy is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Avidity Biosciences, running 2 of these trials.
Enrollment posture brief
Registry condition myotonic-dystrophy
OPEN 7 | RECR 70% | LATE 1 | EARLY 3 | RANK #1724 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Advanced Solid Tumor (70% recruiting · 190 trials)
Myotonic Dystrophy lists 7 open slots (70% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Myotonic Dystrophy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Myotonic Dystrophy is recruiting above its size-band peers.
7 of 10 indexed trials (70%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Myotonic Dystrophy research.
Avidity Biosciences accounts for 2 of 10 trials (20%). 7 distinct sponsors appear on at least one study for this condition label.
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Typical Myotonic Dystrophy enrolment sits around 200 participants.
Median target enrolment is 200 among the 10 trials that report a genuine target (sentinel values excluded). 4 of those (40%) plan for fewer than 100 participants.
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Myotonic Dystrophy research leans observational.
4 interventional and 6 observational studies make up this index (40% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
10 total, page 1 of 1
Myotonic Dystrophy Family Registry
Myotonic Dystrophy Foundation
NCT02398786
Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Registry
University of Rochester
NCT00082108
Biomarker Development for Muscular Dystrophies
Massachusetts General Hospital
NCT05019625
Extracellular RNA Biomarkers of Myotonic Dystrophy
Massachusetts General Hospital
NCT05020002
Trial Readiness and Endpoint Assessment in Pediatric Myotonic Dystrophy Extension
Virginia Commonwealth University
NCT06747884
Development of Quantitative Muscle Imaging as a Biomarker of Disease Endpoints in Myotonic Dystrophy
Wake Forest University Health Sciences
NCT07362875
A Study to Investigate the Safety, Tolerability, and Efficacy of SAR446268, an Adeno-associated Viral Vector-mediated Gene Therapy in Participants Aged 10 to 50 Years of Age With Non-congenital Myotonic Dystrophy Type 1
Sanofi
NCT06844214
Global Study of Del-desiran for the Treatment of DM1
Avidity Biosciences
NCT06411288
Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients
Avidity Biosciences
NCT05479981
Effects of SomatoKine (Iplex)Recombinant Human Insulin-like Growth Factor-1/Recombinant Human Insulin-like Growth Factor-binding Protein-3 (rhIGF-I/rhIGFBP-3) in Myotonic Dystrophy Type 1 (DM1)
University of Rochester
NCT00233519
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 1 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Myotonic Dystrophy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Myotonic Dystrophy trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Myotonic Dystrophy page
10 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 7 Myotonic Dystrophy trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Avidity Biosciences sponsors the most Myotonic Dystrophy trials on record, review their full trial history before evaluating a specific study. See Avidity Biosciences's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Myotonic Dystrophy condition card totals 10 registered trials; most-linked intervention Placebo; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.