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ClinicalTrials.gov 5 recruiting now official registry

Myositis clinical trials

5 of 9 indexed Myositis trials are currently recruiting.

9 US clinical trials · 5 currently recruiting

Myositis is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is argenx, running 2 of these trials.

The research picture

Myositis has 9 registered US clinical trials, 5 of them open to new participants right now, about 56% of the total.

5
recruiting participants now
56%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: argenx
Phase 12Phase 24Phase 31

Active & Recent Trials

9 total, page 1 of 1

RECRUITING 700 participants

MIHRA - Patient-Rooted Insights for Shaping Myositis Science (PRISMS)

Myositis International Health & Research Collaborative Alliance Foundation

NCT07374107

RECRUITING 580 participants

Environmental Risk Factors for the Anti-synthetase Syndrome

National Institute of Environmental Health Sciences (NIEHS)

NCT01276470

RECRUITING Phase 3 318 participants

A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)]

Pfizer

NCT05895786

RECRUITING Phase 2 90 participants

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

Artiva Biotherapeutics

NCT06991114

RECRUITING Phase 1 80 participants

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

CRISPR Therapeutics

NCT06925542

ACTIVE NOT RECRUITING Phase 2 265 participants

A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.

argenx

NCT05523167

ACTIVE NOT RECRUITING Phase 2 36 participants

A Study of Nipocalimab in Participants With Active Idiopathic Inflammatory Myopathies

Janssen Research & Development

NCT05379634

ACTIVE NOT RECRUITING Phase 2 3 participants

A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis

argenx

NCT06284954

COMPLETED Phase 1 19 participants

Study of Pioglitazone in Sporadic Inclusion Body Myositis

Johns Hopkins University

NCT03440034

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 4
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Myositis Trial Landscape

9 indexed Myositis studies · 5 recruiting (56%).

Phase mix: 1 late (III/IV) vs 6 early (I/II).

Top sponsor: argenx (2 trials), 7 others listed. 9 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Myositis?

PlainTrial tracks 9 US clinical trials for Myositis, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Myositis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.