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ClinicalTrials.gov 4 recruiting now early-phase tilt small index

Musculoskeletal Diseases: early-phase trial registry

4 of 12 indexed Musculoskeletal Diseases trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 4 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Musculoskeletal Diseases: 12 US clinical trials tracked, 4 recruiting.

Musculoskeletal Diseases is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Anderson Orthopaedic Research Institute, running 2 of these trials.

Enrollment posture brief

Registry condition musculoskeletal-diseases

OPEN 4 | RECR 33% | LATE 0 | EARLY 1 | RANK #1429 | SPON 2

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Musculoskeletal Diseases (th…33%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Musculoskeletal Diseases

Musculoskeletal Diseases lists 4 open slots (33% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Musculoskeletal Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Musculoskeletal Diseases is recruiting below its size-band peers.

    4 of 12 indexed trials (33.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Musculoskeletal Diseases research.

    Anderson Orthopaedic Research Institute accounts for 2 of 12 trials (16.7%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Typical Musculoskeletal Diseases enrolment sits around 89 participants.

    Median target enrolment is 89 among the 12 trials that report a genuine target (sentinel values excluded). 7 of those (58.3%) plan for fewer than 100 participants.

  4. Musculoskeletal Diseases research is mostly interventional.

    10 interventional and 2 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21

Open and recent trials

12 total, page 1 of 1

RECRUITING 5,000 participants

Prospective SPINE Registry

Xtant Medical

NCT04176562

RECRUITING NA 120 participants

Mode of Exercise and Bone Biomarkers in Older Veterans

VA Office of Research and Development

NCT05266976

RECRUITING 88 participants

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

Xiaojuan Li

NCT04536103

RECRUITING NA 40 participants

The Effects of AFO Heel Height and Stiffness on Gait

University of Iowa

NCT04800484

ACTIVE NOT RECRUITING NA 89 participants

SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization

CrannMed

NCT06550024

ACTIVE NOT RECRUITING NA 60 participants

Impact of Different Exercise Programs on Knee OA

Shirley Ryan AbilityLab

NCT05844124

ACTIVE NOT RECRUITING NA 40 participants

Strength Training Effects on Musculoskeletal Health

Duquesne University

NCT04810975

COMPLETED NA 236 participants

Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty

Anderson Orthopaedic Research Institute

NCT01121146

COMPLETED NA 230 participants

Marathon and Enduron Polyethylene at Long-Term Follow-up

Anderson Orthopaedic Research Institute

NCT02508428

COMPLETED NA 160 participants

Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.

The Cleveland Clinic

NCT02127281

COMPLETED Phase 2 37 participants

Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients

Avidity Biosciences

NCT05479981

COMPLETED NA 12 participants

Effects of a Very Low Carbohydrate Ketogenic Diet or Mediterranean Diet on Markers of Musculoskeletal Health in Older Adults

University of Florida

NCT06203392

Phase Distribution

PhaseTrial count
Phase 2 1

Named interventions

Most-linked intervention names on Musculoskeletal Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Hip Replacement with noncrosslinked Enduron polyethylene Device
1 trials
Hip Replacement with crosslinked Marathon polyethylene Device
1 trials
AOC 1001 Drug
1 trials
Mediterranean diet Other
1 trials
Very low carbohydrate ketogenic diet Other
1 trials
Total Hip Replacement Device
1 trials
SakuraBead Resorbable Microspheres Device
1 trials
Exercise for Knee Osteoarthritis - (Aquatic Walking) Other
1 trials

US sites by state

Facility locations filed on Musculoskeletal Diseases trials. A trial with sites in several states counts in each.

Virginia 4 trials
Ohio 4 trials
Florida 4 trials
Illinois 2 trials
Colorado 2 trials
California 2 trials
Pennsylvania 1 trials
New York 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Musculoskeletal Diseases page

12 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Musculoskeletal Diseases condition card totals 12 registered trials; most-linked intervention Hip Replacement with noncrosslinked Enduron polyethylene; top US site state Virginia. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.