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NCT04536103 · ClinicalTrials.gov registry record
Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry
A clinical trial of Osteoarthritis and Musculoskeletal Diseases, sponsored by Xiaojuan Li.
- Recruiting
- Registry status
- 88
- Enrollment target
- 1
- Study location
NCT04536103 is a study of Osteoarthritis and Musculoskeletal Diseases that is actively recruiting participants, run by Xiaojuan Li. The registered enrollment target is 88 participants, below the 817-participant average among 135 other Osteoarthritis trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04536103, a study of Osteoarthritis and Musculoskeletal Diseases, is actively recruiting participants, sponsored by Xiaojuan Li.
- RECRUITING
- Registry status
- 88 participants
- Enrollment target
- 1
- Study location
Study Summary
Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health. Towards this goal, extensive efforts are ongoing to develop quantitative MRI for cartilage matrix analysis. MR T1ρ and T2 relaxation times have shown to be promising imaging biomarkers for early cartilage degeneration and prediction of disease progression. However, many challenges remain to clinically applying these techniques, including lack of standardized acquisition and quantification methods, and long acquisition times. The study aims to develop novel, fast and reproducible MR T1ρ and T2 relaxation time imaging methods on MR systems from multiple vendors and establish a platform for standardization and cross validation of these measures as a tool for clinical trials using such techniques. Following method validation, patients at risk for osteoarthritis will be tested.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST MRI
Study Locations (1)
Ohio
- Cleveland Clinic Foundation - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2022-04-01 |
| Est. Completion | 2026-12-28 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04536103
The ClinicalTrials.gov registry entry for NCT04536103 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 817-participant average among 135 other Osteoarthritis trials with a reported enrollment target (89% lower). The listed sponsor is Xiaojuan Li, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 6 conditions, with Osteoarthritis appearing as the primary indexed condition, and to 1 intervention - of which MRI is the first listed.
NCT04536103 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.
Frequently Asked Questions
What is clinical trial NCT04536103 about?
NCT04536103 is a clinical study titled "Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry". Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health. Towards this goal, extensive efforts are ongoing to develop quantitative...
What is the current status of trial NCT04536103?
This trial is currently recruiting. The enrollment target is 88 participants. The study started on 2022-04-01. Estimated completion is 2026-12-28.
What conditions does trial NCT04536103 study?
This clinical trial studies the following conditions: Osteoarthritis, Musculoskeletal Diseases, Joint Diseases, ACL Tear, Cartilage Degeneration.
What interventions are being tested in trial NCT04536103?
The interventions under investigation include: MRI (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04536103?
This trial is sponsored by Xiaojuan Li, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04536103 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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