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ClinicalTrials.gov 8 recruiting now official registry

Muscle Weakness clinical trials

Every US clinical trial registered for Muscle Weakness — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

26 US clinical trials · 8 currently recruiting

The research picture

Muscle Weakness has 26 registered US clinical trials, 8 of them open to new participants right now — about 31% of the total.

8
recruiting participants now
31%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
2
top sponsor: The University of Texas Medical Branch, Galveston

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 209 participants

Muscle Recovery After Critical Illness

Kirby Mayer

NCT05537298

RECRUITING Phase 4 80 participants

Depo-Medrol on Psoas After LLIF

Hardeep Singh

NCT05929755

RECRUITING NA 70 participants

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling

University of Colorado, Denver

NCT06129110

RECRUITING NA 60 participants

THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation

The University of Texas Medical Branch, Galveston

NCT06395506

RECRUITING NA 60 participants

Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors

St. Jude Children's Research Hospital

NCT06819475

RECRUITING Phase 1 30 participants

A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

Arcellx

NCT06626919

RECRUITING 23 participants

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

National Institutes of Health Clinical Center (CC)

NCT06998134

RECRUITING NA 16 participants

FIT Exercise in 30d of ULLS-induced Muscle Disuse

Lance Bollinger

NCT06631053

ACTIVE NOT RECRUITING 312 participants

Measuring Outcomes of Activity in Intensive Care

Vanderbilt University Medical Center

NCT03115840

ACTIVE NOT RECRUITING NA 90 participants

Inspiratory Muscle Training Immediately After Lung Transplantation

Ohio State University

NCT05309551

ACTIVE NOT RECRUITING NA 74 participants

Examining the Effects of Vivo on Physical Function and Glycemic Level in Sedentary Older With Prediabetes.

Impactiv

NCT06458530

ACTIVE NOT RECRUITING NA 60 participants

Assessing The Effects of Exercise, Protein, and Electric Stimulation On Intensive Care Unit Patients Outcomes

University of Maryland, Baltimore

NCT02509520

ACTIVE NOT RECRUITING NA 33 participants

HIFEM and Radiofrequency for Muscular System Function Improvement

BTL Industries

NCT06703749

ACTIVE NOT RECRUITING NA 25 participants

Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome

Bijan Najafi, PhD

NCT06238609

COMPLETED Phase 4 201 participants

Best Practice Using Rocuronium and Reversal With Neostigmine or Sugammadex

University of Washington

NCT03543826

COMPLETED Phase 2 108 participants

HORMA: Hormonal Regulators of Muscle and Metabolism in Aging

National Institute on Aging (NIA)

NCT00183040

COMPLETED Phase 4 88 participants

Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly

US Department of Veterans Affairs

NCT00018356

COMPLETED 80 participants

Use of Jumping Mechanography as a Method to Assess Musculoskeletal Status in Older Adults

University of Wisconsin, Madison

NCT00596089

COMPLETED NA 77 participants

Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients

The University of Texas Medical Branch, Galveston

NCT02739464

COMPLETED NA 57 participants

Electrical Stimulation to Strengthen Muscles in the Lower Legs in Patients Requiring Prolonged Mechanical Ventilation

RML Specialty Hospital

NCT01825135

COMPLETED NA 32 participants

Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19

University of Kentucky

NCT04412330

COMPLETED NA 31 participants

Combined Effects of Nutritional and Exercise Countermeasures

University of Arkansas

NCT00447044

COMPLETED Phase 1 19 participants

Electrical Stimulation for Critically Ill Covid-19 Patients

Baylor College of Medicine

NCT04685213

COMPLETED Phase 1 16 participants

Energetics and Function in Older Humans

Baylor College of Medicine

NCT02348762

COMPLETED Phase 2 15 participants

Testosterone Therapy After Hip Fracture in Elderly Women

Washington University School of Medicine

NCT00280267

COMPLETED NA 8 participants

7 Tesla MRI Study in Patients With Statin Related Muscle Complaints

University of Texas Southwestern Medical Center

NCT04575090

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Muscle Weakness Trial Landscape

ClinicalTrials.gov lists 26 US studies indexed under Muscle Weakness, and 8 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Muscle Weakness shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Muscle Weakness is led by The University of Texas Medical Branch, Galveston with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 26 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Muscle Weakness?

PlainTrial tracks 26 US clinical trials for Muscle Weakness, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Muscle Weakness?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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