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Muscle Weakness clinical trials
Every US clinical trial registered for Muscle Weakness — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
26 US clinical trials · 8 currently recruiting
The research picture
Muscle Weakness has 26 registered US clinical trials, 8 of them open to new participants right now — about 31% of the total.
- 8
- recruiting participants now
- 31%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 2
- top sponsor: The University of Texas Medical Branch, Galveston
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Muscle Recovery After Critical Illness
Kirby Mayer
NCT05537298
Depo-Medrol on Psoas After LLIF
Hardeep Singh
NCT05929755
Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling
University of Colorado, Denver
NCT06129110
THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation
The University of Texas Medical Branch, Galveston
NCT06395506
Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors
St. Jude Children's Research Hospital
NCT06819475
A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases
Arcellx
NCT06626919
Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults
National Institutes of Health Clinical Center (CC)
NCT06998134
FIT Exercise in 30d of ULLS-induced Muscle Disuse
Lance Bollinger
NCT06631053
Measuring Outcomes of Activity in Intensive Care
Vanderbilt University Medical Center
NCT03115840
Inspiratory Muscle Training Immediately After Lung Transplantation
Ohio State University
NCT05309551
Examining the Effects of Vivo on Physical Function and Glycemic Level in Sedentary Older With Prediabetes.
Impactiv
NCT06458530
Assessing The Effects of Exercise, Protein, and Electric Stimulation On Intensive Care Unit Patients Outcomes
University of Maryland, Baltimore
NCT02509520
HIFEM and Radiofrequency for Muscular System Function Improvement
BTL Industries
NCT06703749
Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome
Bijan Najafi, PhD
NCT06238609
Best Practice Using Rocuronium and Reversal With Neostigmine or Sugammadex
University of Washington
NCT03543826
HORMA: Hormonal Regulators of Muscle and Metabolism in Aging
National Institute on Aging (NIA)
NCT00183040
Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly
US Department of Veterans Affairs
NCT00018356
Use of Jumping Mechanography as a Method to Assess Musculoskeletal Status in Older Adults
University of Wisconsin, Madison
NCT00596089
Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients
The University of Texas Medical Branch, Galveston
NCT02739464
Electrical Stimulation to Strengthen Muscles in the Lower Legs in Patients Requiring Prolonged Mechanical Ventilation
RML Specialty Hospital
NCT01825135
Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19
University of Kentucky
NCT04412330
Combined Effects of Nutritional and Exercise Countermeasures
University of Arkansas
NCT00447044
Electrical Stimulation for Critically Ill Covid-19 Patients
Baylor College of Medicine
NCT04685213
Energetics and Function in Older Humans
Baylor College of Medicine
NCT02348762
Testosterone Therapy After Hip Fracture in Elderly Women
Washington University School of Medicine
NCT00280267
7 Tesla MRI Study in Patients With Statin Related Muscle Complaints
University of Texas Southwestern Medical Center
NCT04575090
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 2 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Muscle Weakness Trial Landscape
ClinicalTrials.gov lists 26 US studies indexed under Muscle Weakness, and 8 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Muscle Weakness shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Muscle Weakness is led by The University of Texas Medical Branch, Galveston with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 26 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Muscle Weakness?
PlainTrial tracks 26 US clinical trials for Muscle Weakness, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Muscle Weakness?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.