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NCT05309551 · ClinicalTrials.gov registry record · NA

Inspiratory Muscle Training Immediately After Lung Transplantation

A NA study of Muscle Weakness and Rehabilitation, sponsored by Ohio State University.

Active
Registry status
NA
Development phase
90
Enrollment target
1
Study location

NCT05309551 is a NA study of Muscle Weakness and Rehabilitation that is active but no longer recruiting, run by Ohio State University. The registered enrollment target is 90 participants, above the 71-participant average among 25 other Muscle Weakness trials with a reported enrollment target (27% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT05309551, a NA study of Muscle Weakness and Rehabilitation, is active but no longer recruiting, sponsored by Ohio State University.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
90 participants
Enrollment target
1
Study location

Study Summary

Following lung transplantation (LTX), patients may exhibit respiratory and skeletal muscle weakness that will affect exercise capacity, increase dyspnea and fatigue, limit activities of daily living (ADL) and decrease quality of life. Inspiratory muscle training (IMT) has been extensively studied in a variety of non-LTX populations and research has shown that IMT improves exercise capacity, diaphragmatic thickness, and reduced dyspnea during activities of daily living and improved quality of life in patients with advanced lung disease. The aim of this randomized controlled study is to investigate the benefits of providing inspiratory muscle training via use of an inspiratory muscle trainer device in addition to standard physical therapy in the acute phase of rehabilitation following LTX. Patients targeted for enrollment will be those with any type of advanced lung disease requiring LTX with the objective of demonstrating improvements in respiratory muscle recovery, perceived dyspnea, severity of fatigue, and overall functional status following the transplant procedure.

Interventions

  • DEVICE IMT- Intervention group
  • DEVICE IMT- Placebo group

Study Locations (1)

Ohio

  • The Ohio State University Wexner Medical Center - Columbus

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2022-04-20
Est. Completion 2026-05
Phase NA

Sponsor

Ohio State University

552 total trials

What the Registry Record Tells You About NCT05309551

The ClinicalTrials.gov registry entry for NCT05309551 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 71-participant average among 25 other Muscle Weakness trials with a reported enrollment target (27% higher). The listed sponsor is Ohio State University, which has 552 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Muscle Weakness appearing as the primary indexed condition, and to 2 interventions - of which IMT- Intervention group is the first listed.

NCT05309551 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT05309551 about?

NCT05309551 is a clinical study titled "Inspiratory Muscle Training Immediately After Lung Transplantation". Following lung transplantation (LTX), patients may exhibit respiratory and skeletal muscle weakness that will affect exercise capacity, increase dyspnea and fatigue, limit activities of daily living (ADL) and decrease quality of life. Inspiratory muscle training (IMT) has been extensively studied i...

What is the current status of trial NCT05309551?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2022-04-20. Estimated completion is 2026-05.

What conditions does trial NCT05309551 study?

This clinical trial studies the following conditions: Muscle Weakness, Rehabilitation, Lung Transplantation, Chronic Lung Disease.

What interventions are being tested in trial NCT05309551?

The interventions under investigation include: IMT- Intervention group (DEVICE), IMT- Placebo group (DEVICE).

Who is sponsoring clinical trial NCT05309551?

This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05309551 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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