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Muscle Recovery After Critical Illness
NCT05537298 · View on ClinicalTrials.gov ↗
Study Summary
The overarching goal of the proposed study is to determine the trajectories of physical recovery and cellular markers involved with the underlying failure to recover muscle after critical illness, while exploring which characteristics are associated with sustained physical disability. This proposal will examine muscle pathophysiology carefully aligned with physical function outcomes in order to longitudinally assess the recovery, or failed recovery, of muscle function in participants after critical illness: 1. to examine the recovery of muscle and physical function in ICU survivors through longitudinal assessments 2. to investigate the underlying cellular markers and mechanisms of muscle recovery in ICU survivors 3. to determine which cellular markers contribute to physical disability in ICU survivors up to 1 year after hospital admission
Conditions Studied
Study Locations (3)
Alabama
- University of Alabama at Birmingham — Birmingham
Kentucky
- University of Kentucky — Lexington
Oklahoma
- Oklahoma Medical Research Foundation — Oklahoma City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 209 participants |
| Start Date | 2022-10-18 |
| Est. Completion | 2027-08-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05537298
The ClinicalTrials.gov registry entry for NCT05537298 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 209 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Kirby Mayer, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 4 conditions, with Critical Illness appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05537298 reports 3 study locations spanning 3 distinct geographic areas — top geographies include Alabama, Kentucky, Oklahoma. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05537298 about?
NCT05537298 is a clinical study titled "Muscle Recovery After Critical Illness". The overarching goal of the proposed study is to determine the trajectories of physical recovery and cellular markers involved with the underlying failure to recover muscle after critical illness, while exploring which characteristics are associated with sustained physical disability. This proposal ...
What is the current status of trial NCT05537298?
This trial is currently recruiting. The enrollment target is 209 participants. The study started on 2022-10-18. Estimated completion is 2027-08-01.
What conditions does trial NCT05537298 study?
This clinical trial studies the following conditions: Critical Illness, Muscle Weakness, ICU Acquired Weakness, Post Intensive Care Unit Syndrome. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT05537298?
This trial is sponsored by Kirby Mayer, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05537298 being conducted?
This trial has 3 study locations across Alabama, Kentucky, Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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