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ClinicalTrials.gov 16 recruiting now official registry

Mild Cognitive Impairment (MCI) clinical trials

16 of 20 indexed Mild Cognitive Impairment (MCI) trials are currently recruiting.

20 US clinical trials · 16 currently recruiting

Mild Cognitive Impairment (MCI) is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is St. Joseph's Hospital and Medical Center, Phoenix, running 2 of these trials.

The research picture

Mild Cognitive Impairment (MCI) has 20 registered US clinical trials, 16 of them open to new participants right now, about 80% of the total.

16
recruiting participants now
80%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: St. Joseph's Hospital and Medical Center, Phoenix
Phase 22

Active & Recent Trials

20 total, page 1 of 1

RECRUITING NA 240 participants

The "Let's Talk Tech" Tool to Support Decision Making About Technology Use

University of Washington

NCT06817122

RECRUITING Phase 2 240 participants

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

Columbia University

NCT06601933

RECRUITING NA 200 participants

Impact of a Multimodal Lifestyle Intervention on Dementia Risk Factors and Attitude Related to Dementia Risk: A Logistical Pilot Study

HudsonAlpha Institute for Biotechnology

NCT07146412

RECRUITING NA 150 participants

BID WM Digital Intervention in Aging

University of California, San Francisco

NCT06918704

RECRUITING NA 100 participants

Mindfulness for Cognition in Early-stage Alzheimer's Disease

VA Boston Healthcare System

NCT06792877

RECRUITING NA 80 participants

Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations

University of Colorado, Denver

NCT07424365

RECRUITING NA 70 participants

Early-Stage Partner in Care Living Alone Plus

Arizona State University

NCT06962111

RECRUITING 55 participants

A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population

Indivi

NCT07174869

RECRUITING NA 50 participants

Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment

Ohio University

NCT06828926

RECRUITING NA 30 participants

Treating Insomnia in Mild Cognitive Impairment

Beth Israel Deaconess Medical Center

NCT06687161

RECRUITING NA 30 participants

Time Restricted Eating in Alzheimer's Disease

St. Joseph's Hospital and Medical Center, Phoenix

NCT06429124

RECRUITING Phase 2 20 participants

Multi-session Transcranial Alternating Current Stimulation to Improve Dual-task Standing and Brain Activity in Older Adults With Mild Cognitive Impairment

High Point University

NCT07097051

RECRUITING NA 18 participants

Music for the Mind Study

University of Rochester

NCT06866327

RECRUITING NA 16 participants

Remote Sensing for ADRD-Specific Activities Identification in Older Adults

University of Missouri-Columbia

NCT07120347

RECRUITING NA 10 participants

Working Memory Training in Patients with Mild Cognitive Impairment

St. Joseph's Hospital and Medical Center, Phoenix

NCT06734286

RECRUITING NA 7 participants

Memory Support System for Older Chinese Americans With Mild Cognitive Impairment

Icahn School of Medicine at Mount Sinai

NCT07142499

ACTIVE NOT RECRUITING 500 participants

Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)

Marymount University

NCT07180147

COMPLETED 1,182 participants

Alzheimer's Disease Neuroimaging Initiative 2

University of Southern California

NCT01231971

COMPLETED 16 participants

Brain Health Together: Development and Pilot Test

University of California, San Francisco

NCT06914947

COMPLETED NA 15 participants

Self-Administered Interactive Exercise Program (Tele-Exergame)

Baylor College of Medicine

NCT07072962

Phase Distribution

PhaseTrial count
Phase 2 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Mild Cognitive Impairment (MCI) Trial Landscape

20 indexed Mild Cognitive Impairment (MCI) studies · 16 recruiting (80%).

Phase mix: 0 late (III/IV) vs 2 early (I/II).

Top sponsor: St. Joseph's Hospital and Medical Center, Phoenix (2 trials), 9 others listed. 20 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Mild Cognitive Impairment (MCI)?

PlainTrial tracks 20 US clinical trials for Mild Cognitive Impairment (MCI), of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Mild Cognitive Impairment (MCI)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.