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ClinicalTrials.gov 16 recruiting now early-phase tilt

Mild Cognitive Impairment (MCI): early-phase trial registry

16 of 20 indexed Mild Cognitive Impairment (MCI) trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #848 of 28,707 conditions by registered trial count.

20 US clinical trials · 16 currently recruiting · #848 of 28,707 conditions by registered trial count

Mild Cognitive Impairment (MCI): 20 US clinical trials tracked, 16 recruiting.

Mild Cognitive Impairment (MCI) is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is St. Joseph's Hospital and Medical Center, Phoenix, running 2 of these trials.

Enrollment posture brief

Registry condition mild-cognitive-impairment-mci

OPEN 16 | RECR 80% | LATE 0 | EARLY 2 | RANK #848 | SPON 2

Nearest open-share peer: Ablation (80% recruiting · 5 trials)

Mild Cognitive Impairmen (th…80%Advanced or Metastatic Solid55%ALS50%Abdominal Pain25%Acute Myocardial Infarction25%
Open-enrollment share among volume-matched conditions near Mild Cognitive Impairment (MCI)

Mild Cognitive Impairment (MCI) lists 16 open slots (80% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Mild Cognitive Impairment (MCI) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Mild Cognitive Impairment (MCI) is recruiting above its size-band peers.

    16 of 20 indexed trials (80%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Mild Cognitive Impairment (MCI) trials is spread across many organizations.

    St. Joseph's Hospital and Medical Center, Phoenix accounts for 2 of 20 trials (10%). 18 distinct sponsors appear on at least one study for this condition label.

  3. Most Mild Cognitive Impairment (MCI) trials plan to enrol fewer than 100 people.

    Median target enrolment is 55 among the 20 trials that report a genuine target (sentinel values excluded). 13 of those (65%) plan for fewer than 100 participants.

  4. Mild Cognitive Impairment (MCI) research is mostly interventional.

    16 interventional and 4 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 22

Open and recent trials

20 total, page 1 of 1

RECRUITING NA 240 participants

The "Let's Talk Tech" Tool to Support Decision Making About Technology Use

University of Washington

NCT06817122

RECRUITING Phase 2 240 participants

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

Columbia University

NCT06601933

RECRUITING NA 200 participants

Impact of a Multimodal Lifestyle Intervention on Dementia Risk Factors and Attitude Related to Dementia Risk: A Logistical Pilot Study

HudsonAlpha Institute for Biotechnology

NCT07146412

RECRUITING NA 150 participants

BID WM Digital Intervention in Aging

University of California, San Francisco

NCT06918704

RECRUITING NA 100 participants

Mindfulness for Cognition in Early-stage Alzheimer's Disease

VA Boston Healthcare System

NCT06792877

RECRUITING NA 80 participants

Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations

University of Colorado, Denver

NCT07424365

RECRUITING NA 70 participants

Early-Stage Partner in Care Living Alone Plus

Arizona State University

NCT06962111

RECRUITING 55 participants

A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population

Indivi

NCT07174869

RECRUITING NA 50 participants

Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment

Ohio University

NCT06828926

RECRUITING NA 30 participants

Treating Insomnia in Mild Cognitive Impairment

Beth Israel Deaconess Medical Center

NCT06687161

RECRUITING NA 30 participants

Time Restricted Eating in Alzheimer's Disease

St. Joseph's Hospital and Medical Center, Phoenix

NCT06429124

RECRUITING Phase 2 20 participants

Multi-session Transcranial Alternating Current Stimulation to Improve Dual-task Standing and Brain Activity in Older Adults With Mild Cognitive Impairment

High Point University

NCT07097051

RECRUITING NA 18 participants

Music for the Mind Study

University of Rochester

NCT06866327

RECRUITING NA 16 participants

Remote Sensing for ADRD-Specific Activities Identification in Older Adults

University of Missouri-Columbia

NCT07120347

RECRUITING NA 10 participants

Working Memory Training in Patients with Mild Cognitive Impairment

St. Joseph's Hospital and Medical Center, Phoenix

NCT06734286

RECRUITING NA 7 participants

Memory Support System for Older Chinese Americans With Mild Cognitive Impairment

Icahn School of Medicine at Mount Sinai

NCT07142499

ACTIVE NOT RECRUITING 500 participants

Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)

Marymount University

NCT07180147

COMPLETED 1,182 participants

Alzheimer's Disease Neuroimaging Initiative 2

University of Southern California

NCT01231971

COMPLETED 16 participants

Brain Health Together: Development and Pilot Test

University of California, San Francisco

NCT06914947

COMPLETED NA 15 participants

Self-Administered Interactive Exercise Program (Tele-Exergame)

Baylor College of Medicine

NCT07072962

Phase Distribution

PhaseTrial count
Phase 2 2

Named interventions

Most-linked intervention names on Mild Cognitive Impairment (MCI) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

home-based self-administered interactive exercise Device
1 trials
Florbetapir Drug
1 trials
Brain Health Together Behavioral
1 trials
Brain Health Education Behavioral
1 trials
Memory Support System Behavioral
1 trials
Cognitive Training Other
1 trials
sham stimulation Device
1 trials
Waitlist then mindfulness Behavioral
1 trials

US sites by state

Facility locations filed on Mild Cognitive Impairment (MCI) trials. A trial with sites in several states counts in each.

Arizona 4 trials
New York 3 trials
Massachusetts 3 trials
California 3 trials
Washington 2 trials
North Carolina 2 trials
Florida 2 trials
Alabama 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Mild Cognitive Impairment (MCI) page

20 registered trials, 16 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Mild Cognitive Impairment (MCI) condition card totals 20 registered trials; most-linked intervention home-based self-administered interactive exercise; top US site state Arizona. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.