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NCT06601933 · ClinicalTrials.gov registry record · Phase 2

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

A Phase 2 study of Mild Cognitive Impairment (MCI) and Cognitive Training, sponsored by Columbia University.

Recruiting
Registry status
Phase 2
Development phase
240
Enrollment target
4
Study locations

NCT06601933 is a Phase 2 study of Mild Cognitive Impairment (MCI) and Cognitive Training that is actively recruiting participants, run by Columbia University. The registered enrollment target is 240 participants, above the 147-participant average among 19 other Mild Cognitive Impairment (MCI) trials with a reported enrollment target (63% higher). The trial reports 4 study locations across 4 states.

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The verdict

NCT06601933, a Phase 2 study of Mild Cognitive Impairment (MCI) and Cognitive Training, is actively recruiting participants, sponsored by Columbia University.

RECRUITING
Registry status
Phase 2
Development phase
240 participants
Enrollment target
4
Study locations

Study Summary

Effective, clinically meaningful treatments are lacking for patients with mild cognitive impairment (MCI), which is associated with increased risk of transition to dementia. Cognitive training represents an important therapeutic strategy. In a previous study, crossword puzzles were found to be superior to computerized cognitive training on the primary cognitive outcome and function with decreased brain atrophy. Building on these findings, this study will evaluate and compare the impact of high dose crosswords (4 puzzles per week) to low dose crosswords (1 puzzle per week) and a health education control group on the cognition and function of participants.

Conditions Studied

Mild Cognitive Impairment (MCI) Cognitive Training

Interventions

  • OTHER Cognitive Training

Study Locations (4)

Florida

  • University of Miami Miller School of Medicine - Miami

New York

  • Columbia University Irving Medical Center - New York

North Carolina

  • Duke University Medical Center - Durham

Washington

  • University of Washington - Seattle

Trial Details

FieldValue
Enrollment Target 240 participants
Start Date 2024-12-17
Est. Completion 2029-02-28
Phase Phase 2

Sponsor

Columbia University

958 total trials

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What the Registry Record Tells You About NCT06601933

The ClinicalTrials.gov registry entry for NCT06601933 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 147-participant average among 19 other Mild Cognitive Impairment (MCI) trials with a reported enrollment target (63% higher). The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Mild Cognitive Impairment (MCI) appearing as the primary indexed condition, and to 1 intervention - of which Cognitive Training is the first listed.

NCT06601933 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Florida, New York, North Carolina.

Frequently Asked Questions

What is clinical trial NCT06601933 about?

NCT06601933 is a clinical study titled "Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial". Effective, clinically meaningful treatments are lacking for patients with mild cognitive impairment (MCI), which is associated with increased risk of transition to dementia. Cognitive training represents an important therapeutic strategy. In a previous study, crossword puzzles were found to be super...

What is the current status of trial NCT06601933?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 240 participants. The study started on 2024-12-17. Estimated completion is 2029-02-28.

What conditions does trial NCT06601933 study?

This clinical trial studies the following conditions: Mild Cognitive Impairment (MCI), Cognitive Training.

What interventions are being tested in trial NCT06601933?

The interventions under investigation include: Cognitive Training (OTHER).

Who is sponsoring clinical trial NCT06601933?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06601933 being conducted?

This trial has 4 study locations across Florida, New York, North Carolina, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.