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ClinicalTrials.gov 47 recruiting now official registry

Metastatic Cancer clinical trials

47 of 117 indexed Metastatic Cancer trials are currently recruiting.

117 US clinical trials · 47 currently recruiting

Metastatic Cancer is the subject of 117 registered US clinical trials on ClinicalTrials.gov, 47 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 87 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 11 of these trials.

The research picture

Metastatic Cancer has 117 registered US clinical trials, 47 of them open to new participants right now, about 40% of the total.

47
recruiting participants now
40%
of trials open to enrollment
8
in Phase 3–4 (later-stage)
11
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 154Phase 233Phase 38

Active & Recent Trials

117 total, page 3 of 3

COMPLETED Phase 1 24 participants

Sym023 (Anti-TIM-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Symphogen A/S

NCT03489343

COMPLETED Phase 1 14 participants

Study of NG-350A Plus Pembrolizumab in Metastatic or Advanced Epithelial Tumours (FORTIFY)

Akamis Bio

NCT05165433

COMPLETED Phase 1 12 participants

Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)

National Cancer Institute (NCI)

NCT04574583

COMPLETED Phase 1 12 participants

Monoclonal Antibody Therapy in Treating Patients With Colorectal Cancer

Memorial Sloan Kettering Cancer Center

NCT00005616

COMPLETED Phase 1 12 participants

IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors

H. Lee Moffitt Cancer Center and Research Institute

NCT03758781

COMPLETED Phase 1 11 participants

Imiquimod and Laser Therapy With or Without a Green Dye in Treating Patients With Stage III or Stage IV Melanoma That Has Spread to Other Parts of the Skin

University of Oklahoma

NCT00453050

COMPLETED Phase 1 9 participants

Stereotactic Radiation Therapy in Treating Patients With Liver Metastases

Mayo Clinic

NCT00567970

COMPLETED NA 6 participants

Balancing Method for Pain Related to Advanced Cancer

University of Pittsburgh

NCT04176575

COMPLETED Early Phase 1 6 participants

A Novel Method for Treating Lung Met w/Combo of Electric Fields & Rad Therapy: A Single-Arm

University of California, Irvine

NCT05555342

COMPLETED Phase 1 1 participants

Cellular Adoptive Immunotherapy in Treating a Patient Who Has Undergone a Donor Stem Cell Transplant for Breast Cancer That Has Spread to the Lung

National Cancer Institute (NCI)

NCT00301730

COMPLETED Phase 2

Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma

Eastern Cooperative Oncology Group

NCT00003308

COMPLETED Phase 1

Gene Therapy in Treating Patients With Colon Cancer That Has Spread to the Liver

Memorial Sloan Kettering Cancer Center

NCT00012155

COMPLETED Phase 1

Paclitaxel and Hyperthermic Perfusion in Treating Patients With Lung Cancer or Lung Metastases That Cannot Be Removed By Surgery

National Cancer Institute (NCI)

NCT00020007

COMPLETED Phase 3

Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases

Spectrum Pharmaceuticals

NCT00005887

COMPLETED Phase 2

Isolated Hepatic Perfusion With Melphalan Followed by Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer

National Cancer Institute (NCI)

NCT00103298

COMPLETED Phase 3

Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver

National Institutes of Health Clinical Center (CC)

NCT00020501

COMPLETED Phase 2

Surgery With or Without Radiofrequency Ablation Followed by Irinotecan in Treating Patients With Colorectal Cancer That is Metastatic to the Liver

University of Washington

NCT00030563

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Phase Distribution

PhaseTrial count
Phase 1 54
Phase 2 33
Phase 3 8

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Metastatic Cancer Trial Landscape

117 indexed Metastatic Cancer studies · 47 recruiting (40%).

Phase mix: 8 late (III/IV) vs 87 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (11 trials), 9 others listed. 17 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Metastatic Cancer?

PlainTrial tracks 117 US clinical trials for Metastatic Cancer, of which 47 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Metastatic Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.