Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Metastatic Cancer: early-phase trial registry
47 of 117 indexed Metastatic Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #108 of 28,707 conditions by registered trial count.
117 US clinical trials · 47 currently recruiting · #108 of 28,707 conditions by registered trial count
Metastatic Cancer: 117 US clinical trials tracked, 47 recruiting.
Metastatic Cancer is the subject of 117 registered US clinical trials on ClinicalTrials.gov, 47 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 87 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 11 of these trials.
Enrollment posture brief
Registry condition metastatic-cancer
OPEN 47 | RECR 40% | LATE 8 | EARLY 87 | RANK #108 | SPON 11
Volume-matched condition peers
Nearest open-share peer: Knee Osteoarthritis (40% recruiting · 102 trials)
Metastatic Cancer lists 47 open slots (40% of 117 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Metastatic Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Metastatic Cancer is recruiting above its size-band peers.
47 of 117 indexed trials (40.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Metastatic Cancer trials is spread across many organizations.
Memorial Sloan Kettering Cancer Center accounts for 11 of 117 trials (9.4%). 80 distinct sponsors appear on at least one study for this condition label.
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Most Metastatic Cancer trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 110 trials that report a genuine target (sentinel values excluded). 70 of those (63.6%) plan for fewer than 100 participants.
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Metastatic Cancer research is mostly interventional.
108 interventional and 9 observational studies make up this index (92.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
117 total, page 3 of 3
Sym023 (Anti-TIM-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas
Symphogen A/S
NCT03489343
Study of NG-350A Plus Pembrolizumab in Metastatic or Advanced Epithelial Tumours (FORTIFY)
Akamis Bio
NCT05165433
Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)
National Cancer Institute (NCI)
NCT04574583
Monoclonal Antibody Therapy in Treating Patients With Colorectal Cancer
Memorial Sloan Kettering Cancer Center
NCT00005616
IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors
H. Lee Moffitt Cancer Center and Research Institute
NCT03758781
Imiquimod and Laser Therapy With or Without a Green Dye in Treating Patients With Stage III or Stage IV Melanoma That Has Spread to Other Parts of the Skin
University of Oklahoma
NCT00453050
Stereotactic Radiation Therapy in Treating Patients With Liver Metastases
Mayo Clinic
NCT00567970
Balancing Method for Pain Related to Advanced Cancer
University of Pittsburgh
NCT04176575
A Novel Method for Treating Lung Met w/Combo of Electric Fields & Rad Therapy: A Single-Arm
University of California, Irvine
NCT05555342
Cellular Adoptive Immunotherapy in Treating a Patient Who Has Undergone a Donor Stem Cell Transplant for Breast Cancer That Has Spread to the Lung
National Cancer Institute (NCI)
NCT00301730
Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma
Eastern Cooperative Oncology Group
NCT00003308
Gene Therapy in Treating Patients With Colon Cancer That Has Spread to the Liver
Memorial Sloan Kettering Cancer Center
NCT00012155
Paclitaxel and Hyperthermic Perfusion in Treating Patients With Lung Cancer or Lung Metastases That Cannot Be Removed By Surgery
National Cancer Institute (NCI)
NCT00020007
Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases
Spectrum Pharmaceuticals
NCT00005887
Isolated Hepatic Perfusion With Melphalan Followed by Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer
National Cancer Institute (NCI)
NCT00103298
Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver
National Institutes of Health Clinical Center (CC)
NCT00020501
Surgery With or Without Radiofrequency Ablation Followed by Irinotecan in Treating Patients With Colorectal Cancer That is Metastatic to the Liver
University of Washington
NCT00030563
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 54 |
| Phase 2 | 33 |
| Phase 3 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Metastatic Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Metastatic Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Metastatic Cancer page
117 registered trials, 47 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 47 Metastatic Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Memorial Sloan Kettering Cancer Center sponsors the most Metastatic Cancer trials on record, review their full trial history before evaluating a specific study. See Memorial Sloan Kettering Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metastatic Cancer condition card totals 117 registered trials; most-linked intervention quality-of-life assessment; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.