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ClinicalTrials.gov 4 recruiting now official registry

Mental Disorders clinical trials

Every US clinical trial registered for Mental Disorders — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

26 US clinical trials · 4 currently recruiting

The research picture

Mental Disorders has 26 registered US clinical trials, 4 of them open to new participants right now — about 15% of the total.

4
recruiting participants now
15%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
2
top sponsor: University of California, Los Angeles

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 2,000 participants

Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary Care

University of Pittsburgh

NCT06810076

RECRUITING Phase 3 300 participants

Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits

University of Utah

NCT06387290

RECRUITING 80 participants

SQUED™ Series 28.1 Home-use and Treatment of Autowave Reverberator of Autism

American Federation of Medical Synergetics

NCT03222375

RECRUITING NA 30 participants

Stimulation-Induced Changes in Fronto-Limbic Network

University of Alabama at Birmingham

NCT05854160

ACTIVE NOT RECRUITING 6,000 participants

Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression

University of Texas Southwestern Medical Center

NCT06002204

ACTIVE NOT RECRUITING Phase 3 1,175 participants

A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)

Eli Lilly and Company

NCT05738486

ACTIVE NOT RECRUITING NA 90 participants

Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune Mechanisms

Jonsson Comprehensive Cancer Center

NCT00690196

COMPLETED NA 2,956 participants

Family Groups for Urban Youth With Disruptive Behavior

NYU Silver School of Social Work

NCT02715414

COMPLETED Phase 3 837 participants

Study of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder With and Without Anxious Distress

Otsuka Pharmaceutical Development & Commercialization

NCT02196506

COMPLETED 800 participants

Psychiatric Problems in Children and Adolescents Infected With HIV at Birth

International Maternal Pediatric Adolescent AIDS Clinical Trials Group

NCT00100542

COMPLETED NA 428 participants

A Randomized Controlled Trial of Mental Health Peer-Led Education

University of Illinois at Chicago

NCT01297985

COMPLETED Phase 3 300 participants

The Trauma Recovery and Empowerment Model for Treating Post-Traumatic Stress Disorder in Women

Dartmouth-Hitchcock Medical Center

NCT00183716

COMPLETED Phase 1 281 participants

Relative Bioavailability of LY03010 Compared to Listed Drug

Luye Pharma Group

NCT04922593

COMPLETED NA 265 participants

Addressing Mental Health Disparities in Refugee Children: A Community-based Participatory Research (CBPR) Collaboration

Boston College

NCT02562794

COMPLETED 216 participants

The Role of Norepinephrine in Emotional Processing

National Institute of Mental Health (NIMH)

NCT00109642

COMPLETED NA 199 participants

Progressive Goal Attainment Program for Veterans

MDRC

NCT01565863

COMPLETED NA 192 participants

Testing Effectiveness of a Peer-Led Intervention to Enhance Community Integration

Boston University Charles River Campus

NCT02508480

COMPLETED NA 186 participants

My Life: Evaluation of Self-determination Enhancement for Adolescents in Foster Care

Portland State University

NCT02113085

COMPLETED NA 181 participants

Addiction Housing Case Management for Homeless Veterans

VA Office of Research and Development

NCT01346514

COMPLETED NA 172 participants

Adaptive Treatment for Adolescent Cannabis Use Disorders

UConn Health

NCT01656707

COMPLETED Phase 1 96 participants

Study to Compare Two Formulations of Lamotrigine in Healthy Subjects

GlaxoSmithKline

NCT00410371

COMPLETED Phase 4 90 participants

Naltrexone Treatment of Alcohol Abuse in Schizophrenia

State University of New York - Upstate Medical University

NCT00145847

COMPLETED NA 80 participants

Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers

Elizabeth K Rhodus

NCT05202223

COMPLETED NA 61 participants

A System for Preference Assessment in Mental Health

University of California, Los Angeles

NCT02183844

COMPLETED NA 60 participants

Web-Based Weight Management for Individuals With Mental Illness

University of California, Los Angeles

NCT01324973

COMPLETED NA 41 participants

Effects of a Short-term Exercise Intervention on Sleep in Women Exposed to Trauma: A Randomized Controlled Trial

University of Georgia

NCT05097352

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 3 4
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Mental Disorders Trial Landscape

ClinicalTrials.gov lists 26 US studies indexed under Mental Disorders, and 4 of those are currently open to recruitment — roughly 15% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Mental Disorders shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Mental Disorders is led by University of California, Los Angeles with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 26 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Mental Disorders?

PlainTrial tracks 26 US clinical trials for Mental Disorders, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Mental Disorders?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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