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NCT06810076 · ClinicalTrials.gov registry record · NA

Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary Care

A NA study of Substance-Related Disorders and Opioid-Related Disorders, sponsored by University of Pittsburgh.

Recruiting
Registry status
NA
Development phase
2,000
Enrollment target
1
Study location

NCT06810076 is a NA study of Substance-Related Disorders and Opioid-Related Disorders that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 2,000 participants, above the 1,487-participant average among 58 other Substance-Related Disorders trials with a reported enrollment target (34% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT06810076, a NA study of Substance-Related Disorders and Opioid-Related Disorders, is actively recruiting participants, sponsored by University of Pittsburgh.

RECRUITING
Registry status
NA
Development phase
2,000 participants
Enrollment target
1
Study location

Study Summary

This clinical trial aims to evaluate the pilot implementation of a machine-learning (ML)-driven clinical decision support (CDS) tool designed to predict opioid overdose risk within the electronic health record (EHR) system at UF Health Internal Medicine and Family Medicine clinics in Gainesville, Florida. The study will use a pre- versus post-implementation design to compare outcomes within clinics, focusing on measures such as naloxone prescribing rates and opioid overdose occurrences. Researchers will also assess the usability, acceptability, and feasibility of the CDS tool through qualitative interviews with primary care clinicians (PCPs) in the participating clinics.

Interventions

  • BEHAVIORAL Machine Learning-Based Clinical Decision Support: Overdose Prevention Alert (OPA) Intervention

Study Locations (1)

Florida

  • University of Florida Health Internal Medicine and Family Medicine - Gainesville

Trial Details

FieldValue
Enrollment Target 2,000 participants
Start Date 2025-04-08
Est. Completion 2026-10-02
Phase NA

Sponsor

University of Pittsburgh

1,238 total trials

What the Registry Record Tells You About NCT06810076

The ClinicalTrials.gov registry entry for NCT06810076 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 2,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 1,487-participant average among 58 other Substance-Related Disorders trials with a reported enrollment target (34% higher). The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.

The record links to 6 conditions, with Substance-Related Disorders appearing as the primary indexed condition, and to 1 intervention - of which Machine Learning-Based Clinical Decision Support: Overdose Prevention Alert (OPA) Intervention is the first listed.

NCT06810076 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT06810076 about?

NCT06810076 is a clinical study titled "Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary Care". This clinical trial aims to evaluate the pilot implementation of a machine-learning (ML)-driven clinical decision support (CDS) tool designed to predict opioid overdose risk within the electronic health record (EHR) system at UF Health Internal Medicine and Family Medicine clinics in Gainesville, Fl...

What is the current status of trial NCT06810076?

This trial is currently recruiting. It is a NA study. The enrollment target is 2,000 participants. The study started on 2025-04-08. Estimated completion is 2026-10-02.

What conditions does trial NCT06810076 study?

This clinical trial studies the following conditions: Substance-Related Disorders, Opioid-Related Disorders, Mental Disorders, Narcotic-Related Disorders, Chemically-Induced Disorders.

What interventions are being tested in trial NCT06810076?

The interventions under investigation include: Machine Learning-Based Clinical Decision Support: Overdose Prevention Alert (OPA) Intervention (BEHAVIORAL).

Who is sponsoring clinical trial NCT06810076?

This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06810076 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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