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ClinicalTrials.gov 9 recruiting now official registry

Lupus clinical trials

9 of 14 indexed Lupus trials are currently recruiting.

14 US clinical trials · 9 currently recruiting

Lupus is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Allergy and Infectious Diseases (NIAID), running 2 of these trials.

The research picture

Lupus has 14 registered US clinical trials, 9 of them open to new participants right now, about 64% of the total.

9
recruiting participants now
64%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Phase 17Phase 21

Active & Recent Trials

14 total, page 1 of 1

RECRUITING NA 1,650 participants

Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study

Stanford University

NCT05612750

RECRUITING 692 participants

Patient-Centered Assessment of Symptoms and Outcomes

National Center for Complementary and Integrative Health (NCCIH)

NCT03952624

RECRUITING Early Phase 1 61 participants

Safety and Efficacy of ONT01 in Lupus

Hospital for Special Surgery, New York

NCT07107659

RECRUITING Phase 1 47 participants

Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders

M.D. Anderson Cancer Center

NCT06434363

RECRUITING Phase 1 44 participants

A Study to Investigate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986326 in Adult Participants With Different Forms of Lupus

Bristol-Myers Squibb

NCT06013995

RECRUITING NA 30 participants

Helping Lupus Patients Manage Fibromyalgia Symptoms Through Emotional Awareness and Expression Therapy (EAET)

University of Utah

NCT07282392

RECRUITING Phase 1 24 participants

CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

Children's Hospital of Philadelphia

NCT06839976

RECRUITING Phase 1 20 participants

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

National Institute of Allergy and Infectious Diseases (NIAID)

NCT07262983

RECRUITING Phase 1 10 participants

UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients

LiveKidney.Bio

NCT06737380

ACTIVE NOT RECRUITING NA 101 participants

Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity

Brigham and Women's Hospital

NCT05715463

COMPLETED 716 participants

Disease Progression and Activity in Patients With Systemic Lupus Erythematosus

National Institute of Environmental Health Sciences (NIEHS)

NCT00339261

COMPLETED Phase 1 183 participants

A Study to Evaluate the Safety and Tolerability of Multiple Intravenous Doses of MEDI 545 in Patients With Systemic Lupus Erythematosus

MedImmune

NCT00482989

COMPLETED Phase 2 109 participants

JBT-101 in Systemic Lupus Erythematosus (SLE)

National Institute of Allergy and Infectious Diseases (NIAID)

NCT03093402

COMPLETED 19 participants

Evaluation of MyoStrain™ in Clinical Practice

University of Kansas Medical Center

NCT03825224

Reading the Lupus Trial Landscape

14 indexed Lupus studies · 9 recruiting (64%).

Phase mix: 0 late (III/IV) vs 8 early (I/II).

Top sponsor: National Institute of Allergy and Infectious Diseases (NIAID) (2 trials), 9 others listed. 14 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Lupus?

PlainTrial tracks 14 US clinical trials for Lupus, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Lupus?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.