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Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study
NCT05612750 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to conduct a pragmatic clinical trial comparing the effectiveness of: (1) 8-week cognitive behavioral therapy for chronic pain (pain-CBT; sixteen hours total treatment time); and (2) a 1-session pain relief skills intervention for chronic pain (Empowered Relief; two hours total treatment time).
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Behavioral Therapy (CBT)
- BEHAVIORAL Empowered Relief
Study Locations (5)
Arizona
- Phoenix VA Health Care System — Phoenix
California
- SCAN Health Plan — Long Beach
Kentucky
- Humana — Louisville
Pennsylvania
- Lehigh Valley Health Network — Allentown
Utah
- Intermountain Healthcare — Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,650 participants |
| Start Date | 2023-01-01 |
| Est. Completion | 2029-05-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05612750
The ClinicalTrials.gov registry entry for NCT05612750 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,650 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Stanford University, which has 1,643 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Pain, Chronic appearing as the primary indexed condition, and to 2 interventions — of which Cognitive Behavioral Therapy (CBT) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05612750 reports 5 study locations spanning 5 distinct geographic areas — top geographies include Arizona, California, Kentucky. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05612750 about?
NCT05612750 is a clinical study titled "Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study". The purpose of this study is to conduct a pragmatic clinical trial comparing the effectiveness of: (1) 8-week cognitive behavioral therapy for chronic pain (pain-CBT; sixteen hours total treatment time); and (2) a 1-session pain relief skills intervention for chronic pain (Empowered Relief; two hour...
What is the current status of trial NCT05612750?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,650 participants. The study started on 2023-01-01. Estimated completion is 2029-05-01.
What conditions does trial NCT05612750 study?
This clinical trial studies the following conditions: Pain, Chronic, Pelvic Pain, Lupus. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05612750?
The interventions under investigation include: Cognitive Behavioral Therapy (CBT) (BEHAVIORAL), Empowered Relief (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05612750?
This trial is sponsored by Stanford University, which has 1,643 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05612750 being conducted?
This trial has 5 study locations across Arizona, California, Kentucky, Pennsylvania, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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