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ClinicalTrials.gov 41 recruiting now full pipeline #134 of 28,707 conditions

Knee Osteoarthritis: full-pipeline trial registry

41 of 102 indexed Knee Osteoarthritis trials are currently recruiting.

Corpus placement: #134 of 28,707 conditions by registered trial count.

102 US clinical trials · 41 currently recruiting · #134 of 28,707 conditions by registered trial count

Knee Osteoarthritis: 102 US clinical trials tracked, 41 recruiting.

Knee Osteoarthritis is the subject of 102 registered US clinical trials on ClinicalTrials.gov, 41 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 17 in Phase 1-2 (earlier-stage). The most active sponsor is Northwestern University, running 3 of these trials.

Enrollment posture brief

Registry condition knee-osteoarthritis

OPEN 41 | RECR 40% | LATE 14 | EARLY 17 | RANK #134 | SPON 3

Nearest open-share peer: Metastatic Cancer (40% recruiting · 117 trials)

Amyotrophic Lateral Sclerosi45.6%Blood Pressure43.1%Knee Osteoarthritis (this)40%Chronic Kidney Disease31.1%Attention Deficit Hyperactiv28.2%
Open-enrollment share among volume-matched conditions near Knee Osteoarthritis

Knee Osteoarthritis lists 41 open slots (40% of 102 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Knee Osteoarthritis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Knee Osteoarthritis is recruiting above its size-band peers.

    41 of 102 indexed trials (40.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Knee Osteoarthritis trials is spread across many organizations.

    Northwestern University accounts for 3 of 102 trials (2.9%). 77 distinct sponsors appear on at least one study for this condition label.

  3. Typical Knee Osteoarthritis enrolment sits around 83 participants.

    Median target enrolment is 83 among the 102 trials that report a genuine target (sentinel values excluded). 56 of those (54.9%) plan for fewer than 100 participants.

  4. Knee Osteoarthritis research is mostly interventional.

    88 interventional and 14 observational studies make up this index (86.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18Phase 29Phase 36Phase 48

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 9
Phase 3 6
Phase 4 8

Named interventions

Most-linked intervention names on Knee Osteoarthritis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
9 trials
Health Enhancement Program Behavioral
2 trials
Low-carbohydrate diet Behavioral
1 trials
Noxious Electrical Stimulation (NxES) Device
1 trials
Blood Flow Restriction Training (BFRT) Procedure
1 trials
Lorecivivint Drug
1 trials
Placebo Intra-Articular Injection Procedure
1 trials
Standard of Care Intra- Articular Injection Procedure
1 trials

US sites by state

Facility locations filed on Knee Osteoarthritis trials. A trial with sites in several states counts in each.

California 22 trials
Illinois 19 trials
Florida 17 trials
New York 13 trials
North Carolina 12 trials
Texas 11 trials
Pennsylvania 10 trials
Ohio 10 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Knee Osteoarthritis page

102 registered trials, 41 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Knee Osteoarthritis condition card totals 102 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.