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ClinicalTrials.gov 3 recruiting now early-phase tilt small index

IgA Nephropathy: early-phase trial registry

3 of 11 indexed IgA Nephropathy trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 3 currently recruiting · #1,577 of 28,707 conditions by registered trial count

IgA Nephropathy: 11 US clinical trials tracked, 3 recruiting.

IgA Nephropathy is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Novartis Pharmaceuticals, running 3 of these trials.

Enrollment posture brief

Registry condition iga-nephropathy

OPEN 3 | RECR 27% | LATE 4 | EARLY 7 | RANK #1577 | SPON 3

Nearest open-share peer: Atherosclerotic Cardiovascular Disease (27% recruiting · 22 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Acquired Brain Injury36.4%IgA Nephropathy (this)27%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near IgA Nephropathy

IgA Nephropathy lists 3 open slots (27% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for IgA Nephropathy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. IgA Nephropathy is recruiting below its size-band peers.

    3 of 11 indexed trials (27.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates IgA Nephropathy research.

    Novartis Pharmaceuticals accounts for 3 of 11 trials (27.3%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Typical IgA Nephropathy enrolment sits around 103 participants.

    Median target enrolment is 103 among the 11 trials that report a genuine target (sentinel values excluded). 5 of those (45.5%) plan for fewer than 100 participants.

  4. IgA Nephropathy research is mostly interventional.

    11 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 25Phase 33Phase 41

Open and recent trials

11 total, page 1 of 1

RECRUITING Phase 4 60 participants

Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

Calliditas Therapeutics AB

NCT06712407

RECRUITING Phase 2 25 participants

Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue

Otsuka Pharmaceutical Development & Commercialization

NCT06740526

RECRUITING Phase 1 20 participants

Study of BHV-1400 in IgA Nephropathy

Biohaven Therapeutics

NCT07054684

ACTIVE NOT RECRUITING Phase 3 404 participants

Atrasentan in Patients With IgA Nephropathy

Chinook Therapeutics

NCT04573478

ACTIVE NOT RECRUITING Phase 3 383 participants

A Study of Zigakibart in Adults With IgA Nephropathy

Novartis Pharmaceuticals

NCT05852938

ACTIVE NOT RECRUITING Phase 3 376 participants

Atacicept in Subjects With IgA Nephropathy

Vera Therapeutics

NCT04716231

ACTIVE NOT RECRUITING Phase 2 103 participants

Atrasentan in Patients With Proteinuric Glomerular Diseases

Novartis Pharmaceuticals

NCT04573920

ACTIVE NOT RECRUITING Phase 1 103 participants

Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

Novartis Pharmaceuticals

NCT03945318

COMPLETED Phase 2 103 participants

A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX

Biogen

NCT03366337

COMPLETED Phase 2 76 participants

Safety and Efficacy Study of Fostamatinib to Treat Immunoglobin A (IgA) Nephropathy

Rigel Pharmaceuticals

NCT02112838

COMPLETED Phase 2 21 participants

Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies

Apellis Pharmaceuticals

NCT03453619

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 3 3
Phase 4 1

Named interventions

Most-linked intervention names on IgA Nephropathy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
3 trials
Atrasentan Drug
2 trials
Bardoxolone methyl capsules Drug
1 trials
Fostamatinib 100 mg Drug
1 trials
Fostamatinib 150 mg Drug
1 trials
APL-2 Drug
1 trials
Placebo to match Atacicept Other
1 trials
Atacicept Biological
1 trials

US sites by state

Facility locations filed on IgA Nephropathy trials. A trial with sites in several states counts in each.

California 9 trials
Florida 7 trials
Colorado 7 trials
Georgia 6 trials
Texas 5 trials
New York 5 trials
Massachusetts 5 trials
North Carolina 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this IgA Nephropathy page

11 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This IgA Nephropathy condition card totals 11 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.