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ClinicalTrials.gov 3 recruiting now official registry

IgA Nephropathy clinical trials

3 of 11 indexed IgA Nephropathy trials are currently recruiting.

11 US clinical trials · 3 currently recruiting

IgA Nephropathy is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Novartis Pharmaceuticals, running 3 of these trials.

The research picture

IgA Nephropathy has 11 registered US clinical trials, 3 of them open to new participants right now, about 27% of the total.

3
recruiting participants now
27%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
3
top sponsor: Novartis Pharmaceuticals
Phase 12Phase 25Phase 33Phase 41

Active & Recent Trials

11 total, page 1 of 1

RECRUITING Phase 4 60 participants

Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

Calliditas Therapeutics AB

NCT06712407

RECRUITING Phase 2 25 participants

Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue

Otsuka Pharmaceutical Development & Commercialization

NCT06740526

RECRUITING Phase 1 20 participants

Study of BHV-1400 in IgA Nephropathy

Biohaven Therapeutics

NCT07054684

ACTIVE NOT RECRUITING Phase 3 404 participants

Atrasentan in Patients With IgA Nephropathy

Chinook Therapeutics

NCT04573478

ACTIVE NOT RECRUITING Phase 3 383 participants

A Study of Zigakibart in Adults With IgA Nephropathy

Novartis Pharmaceuticals

NCT05852938

ACTIVE NOT RECRUITING Phase 3 376 participants

Atacicept in Subjects With IgA Nephropathy

Vera Therapeutics

NCT04716231

ACTIVE NOT RECRUITING Phase 2 103 participants

Atrasentan in Patients With Proteinuric Glomerular Diseases

Novartis Pharmaceuticals

NCT04573920

ACTIVE NOT RECRUITING Phase 1 103 participants

Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

Novartis Pharmaceuticals

NCT03945318

COMPLETED Phase 2 103 participants

A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX

Biogen

NCT03366337

COMPLETED Phase 2 76 participants

Safety and Efficacy Study of Fostamatinib to Treat Immunoglobin A (IgA) Nephropathy

Rigel Pharmaceuticals

NCT02112838

COMPLETED Phase 2 21 participants

Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies

Apellis Pharmaceuticals

NCT03453619

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 3 3
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the IgA Nephropathy Trial Landscape

11 indexed IgA Nephropathy studies · 3 recruiting (27%).

Phase mix: 4 late (III/IV) vs 7 early (I/II).

Top sponsor: Novartis Pharmaceuticals (3 trials), 8 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for IgA Nephropathy?

PlainTrial tracks 11 US clinical trials for IgA Nephropathy, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for IgA Nephropathy?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.