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NCT05852938 · ClinicalTrials.gov registry record · Phase 3
A Study of Zigakibart in Adults With IgA Nephropathy
A Phase 3 study of Immunoglobulin A Nephropathy and IgA Nephropathy, sponsored by Novartis Pharmaceuticals.
- Active
- Registry status
- Phase 3
- Development phase
- 383
- Enrollment target
- 20
- Study locations
NCT05852938: Active Phase 3 study of Immunoglobulin A Nephropathy and IgA Nephropathy, sponsored by Novartis Pharmaceuticals.
NCT05852938 is a Phase 3 study of Immunoglobulin A Nephropathy and IgA Nephropathy that is active but no longer recruiting, run by Novartis Pharmaceuticals. The registered enrollment target is 383 participants, above the 275-participant average among 13 other Immunoglobulin A Nephropathy trials with a reported enrollment target (39% higher). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05852938, a Phase 3 study of Immunoglobulin A Nephropathy and IgA Nephropathy, is active but no longer recruiting, sponsored by Novartis Pharmaceuticals.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 383 participants
- Enrollment target
- 20
- Study locations
Study Summary
Safety and Efficacy of BION-1301 in Adults with IgA Nephropathy
Primary Outcome
Change from Baseline to Week 104 in eGFR using the CKD-EPI 2021 creatinine equation
Conditions Studied
Interventions
- DRUG Placebo
- DRUG BION-1301
Study Locations (20)
New York
- Capital District Renal Physicians - Clifton Park
- Nephrology Associates PC - Flushing - Flushing
- Icahn School of Medicine at Mount Sinai - New York
Alabama
- University of Alabama at Birmingham: The Kirklin Clinic - Birmingham
- Nephrology Consultants, LLC - Huntsville
California
- University of California, San Francisco - San Francisco
- Valiance Clinical Research - South Gate
Colorado
- University of Colorado Hospital - Aurora
- Denver Nephrology Research Division - Denver
Illinois
- NorthShore University HealthSystem - Evanston
- Nephrology Associales of Northern Illinois and Indiana - Hinsdale
Ohio
- University of Cincinnati College of Medicine - 231 Albert Sabin Way - Cincinnati
- Cleveland Clinic-9500 Euclid Ave - Cleveland
Florida
- Vida Medical Centers - Pembroke Pines - Pembroke Pines
Indiana
- Nephrology Associates of Northern Illinois and Indiana - 7836 W Jefferson Blvd - Fort Wayne
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 383 participants |
| Start Date | 2023-07-06 |
| Est. Completion | 2028-06-07 |
| Phase | Phase 3 |
What the registry record for NCT05852938 still lists
NCT05852938 is an interventional study that assigns participants to a tested intervention. The registered 383 participants enrollment target is mid-sized for trials with a published cap, above the 275-participant average among 13 other Immunoglobulin A Nephropathy trials with a reported enrollment target (39% higher).
The record links to 2 conditions, with Immunoglobulin A Nephropathy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05852938 names 20 study sites across 13 states, led by New York, Alabama, California.
Frequently Asked Questions
What is clinical trial NCT05852938 about?
NCT05852938 is a clinical study titled "A Study of Zigakibart in Adults With IgA Nephropathy". Safety and Efficacy of BION-1301 in Adults with IgA Nephropathy
What is the current status of trial NCT05852938?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 383 participants. The study started on 2023-07-06. Estimated completion is 2028-06-07.
What conditions does trial NCT05852938 study?
This clinical trial studies the following conditions: Immunoglobulin A Nephropathy, IgA Nephropathy.
What interventions are being tested in trial NCT05852938?
The interventions under investigation include: Placebo (DRUG), BION-1301 (DRUG).
Who is sponsoring clinical trial NCT05852938?
This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05852938 being conducted?
This trial has 20 study locations across Alabama, California, Colorado, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Immunoglobulin A Nephropathy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05852938's enrollment target sits among peer trials
383 7th of 13 higher than 7 of 13 other Immunoglobulin A Nephropathy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Immunoglobulin A Nephropathy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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