Rigel Pharmaceuticals

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Rigel Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#696 of 15,742 sponsors by registered trial count).

22 total trials 3 currently recruiting 18 completed early-phase tilt top decile by trial count

Rigel Pharmaceuticals: 22 sponsored US clinical trials, 3 recruiting.

Rigel Pharmaceuticals sponsors 22 registered US clinical trials on ClinicalTrials.gov, 3 of them currently recruiting, and 18 completed. 6 of these trials are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Immune Thrombocytopenic Purpura, with 2 trials.

Top-decile sponsor footprint

Rigel Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#696 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 77/100

18 of 19 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (94.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

22 total, page 1 of 1

RECRUITING Phase 4

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

NCT07486713

RECRUITING Phase 2

Study of Olutasidenib and Temozolomide in HGG

NCT06161974

RECRUITING Phase 1

Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)

NCT05308264

TERMINATED

Observational Study of Fostamatinib as Second Line Therapy in Adult Patients With Immune Thrombocytopenia (ITP) and Insufficient Response to a Prior Therapy

NCT04904276

COMPLETED Phase 3

Double-Blind, Randomized, Placebo-Controlled, Multi-Center Phase 3 Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjects

NCT04629703

COMPLETED Phase 3

A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Study of Fostamatinib Disodium in the Treatment of wAIHA

NCT03764618

COMPLETED Phase 2

A Safety and Efficacy Study of R935788 in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia (AIHA)

NCT02612558

COMPLETED Phase 3

A Efficacy and Safety Study of Fostamatinib in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)

NCT02076412

COMPLETED Phase 2

Safety and Efficacy Study of Fostamatinib to Treat Immunoglobin A (IgA) Nephropathy

NCT02112838

COMPLETED Phase 3

Open Label Study of R788 in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)

NCT02077192

COMPLETED Phase 3

A Efficacy and Safety Study of R935788 in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)

NCT02076399

COMPLETED Phase 2

Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2)

NCT02040623

COMPLETED Phase 2

To Assess the Safety and Efficacy of R932348 Ophthalmic Solutions in Patients With Keratoconjunctivitis Sicca

NCT01900249

COMPLETED Phase 1

A Safety, Tolerability and Pharmacokinetics Study of R932348 Eye Drops in Patients With Dry Eye Disease

NCT01733992

COMPLETED Phase 2

Safety and Efficacy of Topical R333 in Patients With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE) Lesions

NCT01597050

COMPLETED Phase 2

A Safety and Efficacy Study of Inhaled R940343 in Patients With Mild to Moderate Asthma

NCT01591044

COMPLETED Phase 2

Efficacy and Safety Study of Fostamatinib Disodium Tablets to Treat T-Cell Lymphoma

NCT00798096

COMPLETED Phase 2

Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis (Taski-3)

NCT00665626

COMPLETED Phase 2

Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis

NCT00665925

COMPLETED Phase 1

Efficacy and Safety Study of Fostamatinib Tablets to Treat B-cell Lymphoma

NCT00446095

COMPLETED Phase 2

Pilot Study of Fostamatinib Disodium/R935788 for the Treatment of Adult Refractory Immune Thrombocytopenic Purpura (ITP)

NCT00706342

COMPLETED Phase 2

Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)

NCT00326339

What is open in the Rigel Pharmaceuticals pipeline

3 recruiting of 22 indexed (14% open); 18 completed (82%).

Phase mix: 6 late (III/IV) vs 15 early (I/II) (early-phase heavy).

Top condition: Immune Thrombocytopenic Purpura (2 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Rigel Pharmaceuticals: open-pipeline peers nationwide

Peers matched on 22 registered trials and 14% open enrollment, not the therapeutic-area sidebar.

Rigel Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 0%5%10%15% Total trials Recruiting share Rigel PharmaceuticalsAlaunos TherapeuticsAlexza PharmaceuticalsCalithera BiosciencesFate TherapeuticsInMode MDReproductive Medicine Associates of New JerseyBeth Israel Deaconess Medical CenterCase Comprehensive Cancer Center
Rigel Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Rigel Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 22 trials (± recruiting share)

Sponsors near 14% open enrollment (± trial volume)

What to do with this Rigel Pharmaceuticals page

22 registered trials is a research-attention snapshot, not an endorsement of Rigel Pharmaceuticals or any single study.

  • 3 of Rigel Pharmaceuticals's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Immune Thrombocytopenic Purpura is the condition Rigel Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Immune Thrombocytopenic Purpura trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Rigel Pharmaceuticals pipeline card: 22 registered trials from official public datasets.Report a data error.