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Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue
NCT06740526 · View on ClinicalTrials.gov ↗
Study Summary
This is a phase 2b open-label trial to characterize histopathological biomarkers of disease in immunoglobulin A nephropathy (IgAN) and demonstrate potential changes in response to sibeprenlimab.
Conditions Studied
Interventions
- DRUG Sibeprenlimab
Study Locations (5)
Colorado
- Clinical Research Site 330 — Denver
Massachusetts
- Clinical Research Site 369 — Boston
South Dakota
- Clinical Research Site 374 — Dakota Dunes
Texas
- Clinical Research Site 324 — Houston
Ontario
- Clinical Research Site 305 — Scarborough Village
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2024-11-19 |
| Est. Completion | 2029-04-17 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06740526
The ClinicalTrials.gov registry entry for NCT06740526 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Otsuka Pharmaceutical Development & Commercialization, which has 79 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with IgA Nephropathy appearing as the primary indexed condition, and to 1 intervention — of which Sibeprenlimab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06740526 reports 5 study locations spanning 5 distinct geographic areas — top geographies include Colorado, Massachusetts, South Dakota. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06740526 about?
NCT06740526 is a clinical study titled "Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue". This is a phase 2b open-label trial to characterize histopathological biomarkers of disease in immunoglobulin A nephropathy (IgAN) and demonstrate potential changes in response to sibeprenlimab.
What is the current status of trial NCT06740526?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2024-11-19. Estimated completion is 2029-04-17.
What conditions does trial NCT06740526 study?
This clinical trial studies the following conditions: IgA Nephropathy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06740526?
The interventions under investigation include: Sibeprenlimab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06740526?
This trial is sponsored by Otsuka Pharmaceutical Development & Commercialization, which has 79 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06740526 being conducted?
This trial has 5 study locations across Colorado, Massachusetts, South Dakota, Texas, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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