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Hypothyroidism clinical trials
Every US clinical trial registered for Hypothyroidism — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
10 US clinical trials · 7 currently recruiting
The research picture
Hypothyroidism has 10 registered US clinical trials, 7 of them open to new participants right now — about 70% of the total.
- 7
- recruiting participants now
- 70%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Nutraceuticals Research Institute
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
AbbVie
NCT06345339
Natural History of Thyroid Function Disorders
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00001159
Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing
University of Michigan
NCT06629272
A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients
University of California, Irvine
NCT03977207
Dosing of LT4 in Older Individuals
University of Pennsylvania
NCT06073665
Novel Approaches to the Treatment of Hypothyroidism
UConn Health
NCT06731764
Gluten Free Diet in Hashimoto's Hypothyroidism
The Cleveland Clinic
NCT07060118
Detection of Celiac Disease in Patients With Hypothyroidism
University of Vermont
NCT01862510
The Effect of Aroma on Fatigue Scores Among Women With Hypothyroidism
Nutraceuticals Research Institute
NCT03465176
Energy Metabolism in Thyroidectomized Patients
Virginia Commonwealth University
NCT04782856
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 3 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Hypothyroidism Trial Landscape
ClinicalTrials.gov lists 10 US studies indexed under Hypothyroidism, and 7 of those are currently open to recruitment — roughly 70% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Hypothyroidism shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Hypothyroidism is led by Nutraceuticals Research Institute with 1 indexed trial, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 10 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Hypothyroidism?
PlainTrial tracks 10 US clinical trials for Hypothyroidism, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Hypothyroidism?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.