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NCT06731764 · ClinicalTrials.gov registry record · Phase 2
Novel Approaches to the Treatment of Hypothyroidism
A Phase 2 study of Hypothyroidism, sponsored by UConn Health.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 90
- Enrollment target
- 1
- Study location
NCT06731764 is a Phase 2 study of Hypothyroidism that is actively recruiting participants, run by UConn Health. The registered enrollment target is 90 participants, below the 819-participant average among 9 other Hypothyroidism trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06731764, a Phase 2 study of Hypothyroidism, is actively recruiting participants, sponsored by UConn Health.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 90 participants
- Enrollment target
- 1
- Study location
Study Summary
Hypothyroidism is a common condition, more frequent in females, associated with excess of cardiovascular risk and poor quality of life not completely abrogated by treatment with levothyroxine. There is an unmet need to define a safe, effective, and feasible regimen to be applied in large trials aimed at assessing levothyroxine/liothyronine combination therapy in patients living with hypothyroidism. To address this knowledge gap we propose a randomized, three-arm, double-blind, controlled, escalating dose parallel pilot study whose results will lay the foundation of large multicenter trial(s) able to demonstrate the effectiveness (or lack thereof) of levothyroxine/liothyronine combination therapy.
Conditions Studied
Interventions
- DRUG Levothyroxine
- DRUG Levothyroxine/Liothyronine once daily
- DRUG Levothyroxine/Liothyronine twice daily
Study Locations (1)
Connecticut
- UConn Health - Farmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2024-12-10 |
| Est. Completion | 2028-06-30 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06731764
The ClinicalTrials.gov registry entry for NCT06731764 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 9 other Hypothyroidism trials with a reported enrollment target (89% lower). The listed sponsor is UConn Health, which has 178 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hypothyroidism appearing as the primary indexed condition, and to 3 interventions - of which Levothyroxine is the first listed.
NCT06731764 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.
Frequently Asked Questions
What is clinical trial NCT06731764 about?
NCT06731764 is a clinical study titled "Novel Approaches to the Treatment of Hypothyroidism". Hypothyroidism is a common condition, more frequent in females, associated with excess of cardiovascular risk and poor quality of life not completely abrogated by treatment with levothyroxine. There is an unmet need to define a safe, effective, and feasible regimen to be applied in large trials aim...
What is the current status of trial NCT06731764?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 90 participants. The study started on 2024-12-10. Estimated completion is 2028-06-30.
What conditions does trial NCT06731764 study?
This clinical trial studies the following conditions: Hypothyroidism.
What interventions are being tested in trial NCT06731764?
The interventions under investigation include: Levothyroxine (DRUG), Levothyroxine/Liothyronine once daily (DRUG), Levothyroxine/Liothyronine twice daily (DRUG).
Who is sponsoring clinical trial NCT06731764?
This trial is sponsored by UConn Health, which has 178 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06731764 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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