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NCT06629272 · ClinicalTrials.gov registry record · NA
Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing
A NA study of Hypothyroidism, sponsored by University of Michigan.
- Recruiting
- Registry status
- NA
- Development phase
- 900
- Enrollment target
- 3
- Study locations
NCT06629272: Recruiting NA study of Hypothyroidism, sponsored by University of Michigan.
NCT06629272 is a NA study of Hypothyroidism that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 900 participants, above the 729-participant average among 9 other Hypothyroidism trials with a reported enrollment target (23% higher). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06629272, a NA study of Hypothyroidism, is actively recruiting participants, sponsored by University of Michigan.
- RECRUITING
- Registry status
- NA
- Development phase
- 900 participants
- Enrollment target
- 3
- Study locations
Study Summary
The proposed study focuses on testing a novel adapted evidence-based multilevel intervention, Deprescribing Thyroid Hormone In Older Adults (D-THIO), to support thyroid hormone deprescribing (dose de-escalation and/or discontinuation) in older adults with thyroid hormone overtreatment and/or misuse and reduce patient harm. Findings from this study will lay the groundwork for broad implementation of D-THIO and serve as a model for deprescribing inappropriate medications for other endocrine conditions and conditions with biochemical monitoring.
Primary Outcome
Assessed by proportion of patients who had any thyroid hormone dose de-escalation and/or thyroid hormone discontinuation. Thyroid hormone deprescribing is defined as thyroid hormone dose de-escalation and/or discontinuation and will be assessed via Electronic Medical Record (EMR).
Conditions Studied
Interventions
- BEHAVIORAL Enhanced usual care
- BEHAVIORAL D-THIO (Deprescribing Thyroid Hormone In Older Adults)
Study Locations (3)
Michigan
- University of Michigan - Ann Arbor
- Henry Ford Health System - Detroit
California
- University of California San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 900 participants |
| Start Date | 2024-12-02 |
| Est. Completion | 2029-04 |
| Phase | NA |
What NCT06629272 shows while recruiting
NCT06629272 is an interventional study that assigns participants to a tested intervention. The registered 900 participants enrollment target is mid-sized for trials with a published cap, above the 729-participant average among 9 other Hypothyroidism trials with a reported enrollment target (23% higher).
The record links to 1 condition, with Hypothyroidism appearing as the primary indexed condition, and to 2 interventions - of which Enhanced usual care is the first listed.
NCT06629272 reports a single indexed study location in Michigan, California.
Frequently Asked Questions
What is clinical trial NCT06629272 about?
NCT06629272 is a clinical study titled "Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing". The proposed study focuses on testing a novel adapted evidence-based multilevel intervention, Deprescribing Thyroid Hormone In Older Adults (D-THIO), to support thyroid hormone deprescribing (dose de-escalation and/or discontinuation) in older adults with thyroid hormone overtreatment and/or misuse ...
What is the current status of trial NCT06629272?
This trial is currently recruiting. It is a NA study. The enrollment target is 900 participants. The study started on 2024-12-02. Estimated completion is 2029-04.
What conditions does trial NCT06629272 study?
This clinical trial studies the following conditions: Hypothyroidism.
What interventions are being tested in trial NCT06629272?
The interventions under investigation include: Enhanced usual care (BEHAVIORAL), D-THIO (Deprescribing Thyroid Hormone In Older Adults) (BEHAVIORAL).
Who is sponsoring clinical trial NCT06629272?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06629272 being conducted?
This trial has 3 study locations across California, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypothyroidism
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06629272's enrollment target sits among peer trials
900 3rd of 9 higher than 7 of 9 other Hypothyroidism trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypothyroidism trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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