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Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing
NCT06629272 · View on ClinicalTrials.gov ↗
Study Summary
The proposed study focuses on testing a novel adapted evidence-based multilevel intervention, Deprescribing Thyroid Hormone In Older Adults (D-THIO), to support thyroid hormone deprescribing (dose de-escalation and/or discontinuation) in older adults with thyroid hormone overtreatment and/or misuse and reduce patient harm. Findings from this study will lay the groundwork for broad implementation of D-THIO and serve as a model for deprescribing inappropriate medications for other endocrine conditions and conditions with biochemical monitoring.
Conditions Studied
Interventions
- BEHAVIORAL Enhanced usual care
- BEHAVIORAL D-THIO (Deprescribing Thyroid Hormone In Older Adults)
Study Locations (3)
Michigan
- University of Michigan — Ann Arbor
- Henry Ford Health System — Detroit
California
- University of California San Francisco — San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 900 participants |
| Start Date | 2024-12-02 |
| Est. Completion | 2029-04 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06629272
The ClinicalTrials.gov registry entry for NCT06629272 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 900 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan, which has 1,126 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Hypothyroidism appearing as the primary indexed condition, and to 2 interventions — of which Enhanced usual care is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06629272 reports 3 study locations spanning 2 distinct geographic areas — top geographies include Michigan, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06629272 about?
NCT06629272 is a clinical study titled "Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing". The proposed study focuses on testing a novel adapted evidence-based multilevel intervention, Deprescribing Thyroid Hormone In Older Adults (D-THIO), to support thyroid hormone deprescribing (dose de-escalation and/or discontinuation) in older adults with thyroid hormone overtreatment and/or misuse ...
What is the current status of trial NCT06629272?
This trial is currently recruiting. It is a NA study. The enrollment target is 900 participants. The study started on 2024-12-02. Estimated completion is 2029-04.
What conditions does trial NCT06629272 study?
This clinical trial studies the following conditions: Hypothyroidism. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06629272?
The interventions under investigation include: Enhanced usual care (BEHAVIORAL), D-THIO (Deprescribing Thyroid Hormone In Older Adults) (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06629272?
This trial is sponsored by University of Michigan, which has 1,126 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06629272 being conducted?
This trial has 3 study locations across California, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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