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Hypogonadism, Male clinical trials
Every US clinical trial registered for Hypogonadism, Male — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
13 US clinical trials · 6 currently recruiting
The research picture
Hypogonadism, Male has 13 registered US clinical trials, 6 of them open to new participants right now — about 46% of the total.
- 6
- recruiting participants now
- 46%
- of trials open to enrollment
- 4
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Seattle Institute for Biomedical and Clinical Research
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Testosterone Replacement in Male Cancer Survivors With Fatigue and Low Testosterone
Seattle Institute for Biomedical and Clinical Research
NCT04049331
Improving Cancer-related Fatigue, Sexual Dysfunction and Quality of Life in Older Men With Cancer and Androgen Deficiency
Seattle Institute for Biomedical and Clinical Research
NCT04301765
Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism
Brigham and Women's Hospital
NCT04798469
EndoPAT Device for Endothelial Dysfunction in ED
University of California, Irvine
NCT06720597
52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism
Halozyme Therapeutics
NCT06689085
Testosterone Treatment in Men with Chronic Kidney Disease
St. Louis University
NCT05249634
TRT as an Adjunctive ERAS Therapy in ESRD Patients Undergoing Kidney Transplantation
University of California, Los Angeles
NCT07287800
Ambulatory Blood Pressure Monitoring in Oral Testosterone Undecanoate (TU, LPCN 1021) Treated Hypogonadal Men
Lipocine
NCT03868059
Vogelxo(R) ABPM Study in Hypogandal Men
Upsher-Smith Laboratories
NCT04558567
A Comparison of Side Effects in Hypogonadal Men Treated With Natesto Versus Testosterone Injections
University of Miami
NCT04439799
28-Day Study of Testosterone Co-administered With Dutasteride in Hypogonadal Men
GlaxoSmithKline
NCT00398580
Clomid in Men With Low Testosterone With and Without Prior Treatment
Phoenix VA Health Care System
NCT01904734
Assessment of Blood From Men Receiving Oral TU in Various Collection Tubes
Clarus Therapeutics
NCT03973840
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 6 |
| Phase 3 | 2 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Hypogonadism, Male Trial Landscape
ClinicalTrials.gov lists 13 US studies indexed under Hypogonadism, Male, and 6 of those are currently open to recruitment — roughly 46% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Hypogonadism, Male shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Hypogonadism, Male is led by Seattle Institute for Biomedical and Clinical Research with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Hypogonadism, Male?
PlainTrial tracks 13 US clinical trials for Hypogonadism, Male, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Hypogonadism, Male?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.