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NCT00398580 · ClinicalTrials.gov registry record · Phase 2

28-Day Study of Testosterone Co-administered With Dutasteride in Hypogonadal Men

A Phase 2 study of Hypogonadism and Hypogonadism, Male, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 2
Development phase
43
Enrollment target
7
Study locations

NCT00398580 is a Phase 2 study of Hypogonadism and Hypogonadism, Male that has completed, run by GlaxoSmithKline. The registered enrollment target is 43 participants, below the 118-participant average among 21 other Hypogonadism trials with a reported enrollment target (64% lower). The trial reports 7 study locations across 6 states.

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The verdict

NCT00398580, a Phase 2 study of Hypogonadism and Hypogonadism, Male, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 2
Development phase
43 participants
Enrollment target
7
Study locations

Study Summary

The combination of testosterone and dutasteride is intended for use in hypogonadal men. This study will evaluate the effect of 28-day repeat dosing of this combination with varying BID doses of testosterone (T), in combination with a fixed BID dose of dutasteride (D), as well as a testosterone alone arm, on T and D levels in the blood. The rationale is to look for the effects of each compound on the other, and to look for any safety problems that may result when the 2 drugs are given together.

Interventions

  • DRUG Nanomilled testosterone
  • DRUG Nanomilled dutasteride
  • DRUG commercially available dutasteride

Study Locations (7)

Washington

  • GSK Investigational Site - Seattle
  • GSK Investigational Site - Seattle

California

  • GSK Investigational Site - Torrance

Kentucky

  • GSK Investigational Site - Louisville

Maryland

  • GSK Investigational Site - Baltimore

North Carolina

  • GSK Investigational Site - Durham

Texas

  • GSK Investigational Site - San Antonio

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 2006-10
Est. Completion 2007-10
Phase Phase 2

Sponsor

GlaxoSmithKline

1,345 total trials

What the Registry Record Tells You About NCT00398580

The ClinicalTrials.gov registry entry for NCT00398580 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 43 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 118-participant average among 21 other Hypogonadism trials with a reported enrollment target (64% lower). The listed sponsor is GlaxoSmithKline, which has 1,345 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Hypogonadism appearing as the primary indexed condition, and to 3 interventions - of which Nanomilled testosterone is the first listed.

NCT00398580 reports 7 study locations spanning 6 distinct geographic areas - top geographies include Washington, California, Kentucky.

Frequently Asked Questions

What is clinical trial NCT00398580 about?

NCT00398580 is a clinical study titled "28-Day Study of Testosterone Co-administered With Dutasteride in Hypogonadal Men". The combination of testosterone and dutasteride is intended for use in hypogonadal men. This study will evaluate the effect of 28-day repeat dosing of this combination with varying BID doses of testosterone (T), in combination with a fixed BID dose of dutasteride (D), as well as a testosterone alone...

What is the current status of trial NCT00398580?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 43 participants. The study started on 2006-10. Estimated completion is 2007-10.

What conditions does trial NCT00398580 study?

This clinical trial studies the following conditions: Hypogonadism, Hypogonadism, Male.

What interventions are being tested in trial NCT00398580?

The interventions under investigation include: Nanomilled testosterone (DRUG), Nanomilled dutasteride (DRUG), commercially available dutasteride (DRUG).

Who is sponsoring clinical trial NCT00398580?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00398580 being conducted?

This trial has 7 study locations across California, Kentucky, Maryland, North Carolina, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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