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ClinicalTrials.gov 6 recruiting now official registry

Hypertrophic Cardiomyopathy clinical trials

6 of 12 indexed Hypertrophic Cardiomyopathy trials are currently recruiting.

12 US clinical trials · 6 currently recruiting

Hypertrophic Cardiomyopathy is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Mayo Clinic, running 2 of these trials.

The research picture

Hypertrophic Cardiomyopathy has 12 registered US clinical trials, 6 of them open to new participants right now, about 50% of the total.

6
recruiting participants now
50%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Mayo Clinic
Phase 11Phase 21

Active & Recent Trials

12 total, page 1 of 1

RECRUITING 5,000 participants

Cardiovascular Multimodality Imaging Study

Montefiore Medical Center

NCT06610019

RECRUITING 500 participants

VIZ ACCESS HCM - Multi-Site Registry

Viz.ai

NCT07103057

RECRUITING 300 participants

Pediatric Cardiomyopathy Mutation Analysis

Indiana University

NCT02432092

RECRUITING NA 70 participants

Exercise Intolerance in Non-obstructive Hypertrophic Cardiomyopathy

University of California, San Francisco

NCT05818605

RECRUITING Phase 1 30 participants

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

Tenaya Therapeutics

NCT05836259

RECRUITING 20 participants

Mavacamten Pregnancy Surveillance Program

Bristol-Myers Squibb

NCT05939700

ACTIVE NOT RECRUITING 2,750 participants

HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy

University of Virginia

NCT01915615

ACTIVE NOT RECRUITING 260 participants

A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy

Mayo Clinic

NCT04112290

ACTIVE NOT RECRUITING 183 participants

A Study of Artificial Intelligence ECG With ECG Devices to Detect Hypertrophic Cardiomyopathy Distinct From Athlete's

Mayo Clinic

NCT06290570

ACTIVE NOT RECRUITING Phase 2 100 participants

A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)

Edgewise Therapeutics

NCT06347159

COMPLETED 4,299 participants

Exercise in Genetic Cardiovascular Conditions

Yale University

NCT02549664

COMPLETED

Screening for Inherited Heart Disease

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001746

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Hypertrophic Cardiomyopathy Trial Landscape

12 indexed Hypertrophic Cardiomyopathy studies · 6 recruiting (50%).

Phase mix: 0 late (III/IV) vs 2 early (I/II).

Top sponsor: Mayo Clinic (2 trials), 9 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Hypertrophic Cardiomyopathy?

PlainTrial tracks 12 US clinical trials for Hypertrophic Cardiomyopathy, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Hypertrophic Cardiomyopathy?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.