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ClinicalTrials.gov 6 recruiting now official registry

Hypertrophic Cardiomyopathy clinical trials

Every US clinical trial registered for Hypertrophic Cardiomyopathy — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

12 US clinical trials · 6 currently recruiting

The research picture

Hypertrophic Cardiomyopathy has 12 registered US clinical trials, 6 of them open to new participants right now — about 50% of the total.

6
recruiting participants now
50%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Mayo Clinic

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 5,000 participants

Cardiovascular Multimodality Imaging Study

Montefiore Medical Center

NCT06610019

RECRUITING 500 participants

VIZ ACCESS HCM - Multi-Site Registry

Viz.ai

NCT07103057

RECRUITING 300 participants

Pediatric Cardiomyopathy Mutation Analysis

Indiana University

NCT02432092

RECRUITING NA 70 participants

Exercise Intolerance in Non-obstructive Hypertrophic Cardiomyopathy

University of California, San Francis

NCT05818605

RECRUITING Phase 1 30 participants

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

Tenaya Therapeutics

NCT05836259

RECRUITING 20 participants

Mavacamten Pregnancy Surveillance Program

Bristol-Myers Squibb

NCT05939700

ACTIVE NOT RECRUITING 2,750 participants

HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy

University of Virginia

NCT01915615

ACTIVE NOT RECRUITING 260 participants

A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy

Mayo Clinic

NCT04112290

ACTIVE NOT RECRUITING 183 participants

A Study of Artificial Intelligence ECG With ECG Devices to Detect Hypertrophic Cardiomyopathy Distinct From Athlete's

Mayo Clinic

NCT06290570

ACTIVE NOT RECRUITING Phase 2 100 participants

A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)

Edgewise Therapeutics

NCT06347159

COMPLETED 4,299 participants

Exercise in Genetic Cardiovascular Conditions

Yale University

NCT02549664

COMPLETED

Screening for Inherited Heart Disease

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001746

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Hypertrophic Cardiomyopathy Trial Landscape

ClinicalTrials.gov lists 12 US studies indexed under Hypertrophic Cardiomyopathy, and 6 of those are currently open to recruitment — roughly 50% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Hypertrophic Cardiomyopathy shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Hypertrophic Cardiomyopathy is led by Mayo Clinic with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 12 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Hypertrophic Cardiomyopathy?

PlainTrial tracks 12 US clinical trials for Hypertrophic Cardiomyopathy, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Hypertrophic Cardiomyopathy?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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