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NCT05818605 · ClinicalTrials.gov registry record · NA

Exercise Intolerance in Non-obstructive Hypertrophic Cardiomyopathy

A NA study of Hypertrophic Cardiomyopathy, sponsored by University of California, San Francisco.

Recruiting
Registry status
NA
Development phase
70
Enrollment target
1
Study location

NCT05818605: Recruiting NA study of Hypertrophic Cardiomyopathy, sponsored by University of California, San Francisco.

NCT05818605 is a NA study of Hypertrophic Cardiomyopathy that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 70 participants, below the 1,344-participant average among 10 other Hypertrophic Cardiomyopathy trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05818605, a NA study of Hypertrophic Cardiomyopathy, is actively recruiting participants, sponsored by University of California, San Francisco.

RECRUITING
Registry status
NA
Development phase
70 participants
Enrollment target
1
Study location

Study Summary

The EXCITE-HCM study is a randomized, controlled, blinded clinical trial designed to evaluate the effect of moderate intensity exercise training versus usual physicial activity on the improvement of HCM-related symptoms and cardiac function. About 70 participants will be recruited and randomized on a 1:1 ratio to either moderate intensity training or usual physicial activity interventions. Patients will be followed during a period of 24 weeks and assesesments as physical examination, questionnaires, 12 lead ecg's, biomarker levels, echocardiogram, Cardiac Magnetic resonance, PET and CPET will be performed to evaluate their response to the intervention.

Primary Outcome

Change in peak oxygen consumption (V O2 max: mL/kg/min) by CPET

Interventions

  • BEHAVIORAL Moderate Intensity Exercise Program

Study Locations (1)

California

  • University of California - San Francisco - San Francisco

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2023-02-17
Est. Completion 2027-03-01
Phase NA

What NCT05818605 shows while recruiting

NCT05818605 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 1,344-participant average among 10 other Hypertrophic Cardiomyopathy trials with a reported enrollment target (95% lower).

The record links to 1 condition, with Hypertrophic Cardiomyopathy appearing as the primary indexed condition, and to 1 intervention - of which Moderate Intensity Exercise Program is the first listed.

NCT05818605 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT05818605 about?

NCT05818605 is a clinical study titled "Exercise Intolerance in Non-obstructive Hypertrophic Cardiomyopathy". The EXCITE-HCM study is a randomized, controlled, blinded clinical trial designed to evaluate the effect of moderate intensity exercise training versus usual physicial activity on the improvement of HCM-related symptoms and cardiac function. About 70 participants will be recruited and randomized on ...

What is the current status of trial NCT05818605?

This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2023-02-17. Estimated completion is 2027-03-01.

What conditions does trial NCT05818605 study?

This clinical trial studies the following conditions: Hypertrophic Cardiomyopathy.

What interventions are being tested in trial NCT05818605?

The interventions under investigation include: Moderate Intensity Exercise Program (BEHAVIORAL).

Who is sponsoring clinical trial NCT05818605?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05818605 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Hypertrophic Cardiomyopathy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05818605's enrollment target sits among peer trials

70 9th of 10 higher than 2 of 10 other Hypertrophic Cardiomyopathy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Hypertrophic Cardiomyopathy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05818605, the US trial registry maintained by the National Library of Medicine. NCT05818605 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.