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NCT03729778 · ClinicalTrials.gov registry record · Early Phase 1

Impact of HIV-1 and Aging on Mucosal Vaccine Responses

A Early Phase 1 study of HIV Infections and HIV-1-infection, sponsored by VA Eastern Colorado Health Care System.

Active
Registry status
Early Phase 1
Development phase
100
Enrollment target
1
Study location

NCT03729778: Active Early Phase 1 study of HIV Infections and HIV-1-infection, sponsored by VA Eastern Colorado Health Care System.

NCT03729778 is a Early Phase 1 study of HIV Infections and HIV-1-infection that is active but no longer recruiting, run by VA Eastern Colorado Health Care System. The registered enrollment target is 100 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03729778, a Early Phase 1 study of HIV Infections and HIV-1-infection, is active but no longer recruiting, sponsored by VA Eastern Colorado Health Care System.

ACTIVE NOT RECRUITING
Registry status
Early Phase 1
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to learn more about both HIV-1 infection and advancing age, and their association with increased risk of serious infection and impaired response to the Prevnar 13 vaccine.

Primary Outcome

Determine pneumococcal specific IgG levels in BAL fluid and NPF and to standardize the results we will compare it to the total levels in the BAL/NPF fluid collected at all timepoints

Interventions

  • BIOLOGICAL Prevnar-13

Study Locations (1)

Colorado

  • Rocky Mountain Regional VA Medical Center - Aurora

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2017-01-18
Est. Completion 2028-01-01
Phase Early Phase 1

What the registry record for NCT03729778 still lists

NCT03729778 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (78% lower).

The record links to 4 conditions, with HIV Infections appearing as the primary indexed condition, and to 1 intervention - of which Prevnar-13 is the first listed.

NCT03729778 reports a single indexed study location in Colorado.

Frequently Asked Questions

What is clinical trial NCT03729778 about?

NCT03729778 is a clinical study titled "Impact of HIV-1 and Aging on Mucosal Vaccine Responses". The purpose of this study is to learn more about both HIV-1 infection and advancing age, and their association with increased risk of serious infection and impaired response to the Prevnar 13 vaccine.

What is the current status of trial NCT03729778?

This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 100 participants. The study started on 2017-01-18. Estimated completion is 2028-01-01.

What conditions does trial NCT03729778 study?

This clinical trial studies the following conditions: HIV Infections, HIV-1-infection, HIV/AIDS, Human Immunodeficiency Virus.

What interventions are being tested in trial NCT03729778?

The interventions under investigation include: Prevnar-13 (BIOLOGICAL).

Who is sponsoring clinical trial NCT03729778?

This trial is sponsored by VA Eastern Colorado Health Care System, which has 42 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03729778 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV Infections

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03729778's enrollment target sits among peer trials

100 267th of 542 higher than 267 of 542 other HIV Infections trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03729778, the US trial registry maintained by the National Library of Medicine. NCT03729778 (mid enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.