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ClinicalTrials.gov 56 recruiting now early-phase tilt #7 of 28,707 conditions

HIV Infections: early-phase trial registry

56 of 615 indexed HIV Infections trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #7 of 28,707 conditions by registered trial count.

615 US clinical trials · 56 currently recruiting · #7 of 28,707 conditions by registered trial count

HIV Infections: 615 US clinical trials tracked, 56 recruiting.

HIV Infections is the subject of 615 registered US clinical trials on ClinicalTrials.gov, 56 of them currently open to new participants. 92 are in Phase 3-4 (later-stage) and 266 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Allergy and Infectious Diseases (NIAID), running 195 of these trials.

Enrollment posture brief

Registry condition hiv-infections

OPEN 56 | RECR 9% | LATE 92 | EARLY 266 | RANK #7 | SPON 195

Nearest open-share peer: Acute Lung Injury (9% recruiting · 11 trials)

Cancer44.9%Prostate Cancer36.7%Depression35.7%Hypertension32.2%HIV Infections (this)9%
Open-enrollment share among volume-matched conditions near HIV Infections

HIV Infections lists 56 open slots (9% of 615 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for HIV Infections on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. HIV Infections is recruiting below its size-band peers.

    56 of 615 indexed trials (9.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates HIV Infections research.

    National Institute of Allergy and Infectious Diseases (NIAID) accounts for 195 of 615 trials (31.7%). 173 distinct sponsors appear on at least one study for this condition label.

  3. Typical HIV Infections enrolment sits around 100 participants.

    Median target enrolment is 100 among the 543 trials that report a genuine target (sentinel values excluded). 267 of those (49.2%) plan for fewer than 100 participants.

  4. HIV Infections research is mostly interventional.

    549 interventional and 66 observational studies make up this index (89.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1157Phase 2109Phase 369Phase 423

Open and recent trials

615 total, page 13 of 13

COMPLETED NA

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS and Advanced ARC Patients With Anemia

Ortho Pharmaceuticals

NCT00002042

COMPLETED NA

A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients

Glaxo Wellcome

NCT00002084

COMPLETED Phase 1

Phase I/II Study of Curdlan Sulfate

AJI Pharma U

NCT00002100

COMPLETED NA

A Study to Evaluate the Effect of Cimetidine on CD4 Lymphocyte Counts in HIV Infection

Community Research Initiative of New England

NCT00002092

COMPLETED Phase 3

A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes

Hoffmann-La Roche

NCT00002377

COMPLETED NA

A Prospective Double-Blind Study of Retrovir in Early HIV Infection

Glaxo Wellcome

NCT00002045

COMPLETED Phase 2

A Study of Thymic Humoral Factor (THF Gamma 2) in HIV-Infected Patients

Pharmacia

NCT00002435

COMPLETED Phase 2

A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis

Agouron Pharmaceuticals

NCT00002169

COMPLETED NA

A Study of Trimetrexate Plus Leucovorin in Children With Pneumocystis Carinii Pneumonia

U.S. Bioscience

NCT00002317

COMPLETED Phase 1

A Phase I/II Pilot Study of Simultaneously Administered Rhu GM-CSF ( CHO Cell ) and Azidothymidine ( AZT ) in Patients With Severe HIV Infection and Leukopenia: Pharmacokinetics and Feasibility

Sandoz

NCT00002006

COMPLETED NA

A Double-Blind Group Comparative Study To Evaluate the Long-Term Safety and Effectiveness of Two Different Doses of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients With Multiple Episodes of PCP

Fisons

NCT00002055

COMPLETED NA

A Study of ddC in Patients With AIDS or Advanced AIDS-Related Complex (ARC) Who Have Not Had Success With Zidovudine (AZT)

Hoffmann-La Roche

NCT00002279

COMPLETED NA

A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate (Neutrexin) With Leucovorin Protection for European Adult Patients (>= 13 Years Old) With Pneumocystis Carinii Pneumonia

U.S. Bioscience

NCT00002103

COMPLETED NA

Double Blind Study of Thymopentin Effects on HIV-1 Infectivity of Blood Mononuclear Cells and Semen in HIV Infected Patients

Immunobiology Research Institute

NCT00002049

COMPLETED Phase 1

Phase I Study of the Clinical Pharmacology of Azithromycin in Buffy Coat of HIV-Infected Subjects.

Pfizer

NCT00002139

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Phase Distribution

PhaseTrial count
Phase 1 157
Phase 2 109
Phase 3 69
Phase 4 23

Named interventions

Most-linked intervention names on HIV Infections records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Zidovudine Drug
65 trials
Indinavir sulfate Drug
23 trials
Lamivudine Drug
23 trials
Didanosine Drug
22 trials
Stavudine Drug
19 trials
Ritonavir Drug
18 trials
Abacavir sulfate Drug
15 trials
Nelfinavir mesylate Drug
15 trials

US sites by state

Facility locations filed on HIV Infections trials. A trial with sites in several states counts in each.

California 303 trials
New York 205 trials
Florida 177 trials
Illinois 152 trials
Massachusetts 142 trials
Maryland 126 trials
Colorado 107 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this HIV Infections page

615 registered trials, 56 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This HIV Infections condition card totals 615 registered trials; most-linked intervention Zidovudine; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.