Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 8 recruiting now early-phase tilt small index

Heart Failure, Systolic: early-phase trial registry

8 of 14 indexed Heart Failure, Systolic trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 8 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Heart Failure, Systolic: 14 US clinical trials tracked, 8 recruiting.

Heart Failure, Systolic is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Sardocor, running 1 of these trials.

Enrollment posture brief

Registry condition heart-failure-systolic

OPEN 8 | RECR 57% | LATE 0 | EARLY 4 | RANK #1230 | SPON 1

Nearest open-share peer: ACL (57% recruiting · 7 trials)

Heart Failure, Systolic (thi…57%Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Abscess7.1%
Open-enrollment share among volume-matched conditions near Heart Failure, Systolic

Heart Failure, Systolic lists 8 open slots (57% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Heart Failure, Systolic on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Heart Failure, Systolic is recruiting above its size-band peers.

    8 of 14 indexed trials (57.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Heart Failure, Systolic trials is spread across many organizations.

    Sardocor accounts for 1 of 14 trials (7.1%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Most Heart Failure, Systolic trials plan to enrol fewer than 100 people.

    Median target enrolment is 57 among the 14 trials that report a genuine target (sentinel values excluded). 10 of those (71.4%) plan for fewer than 100 participants.

  4. Heart Failure, Systolic research is mostly interventional.

    12 interventional and 2 observational studies make up this index (85.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14

Open and recent trials

14 total, page 1 of 1

RECRUITING NA 754 participants

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

Sunnybrook Health Sciences Centre

NCT05427370

RECRUITING NA 516 participants

MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation

University of California, San Francisco

NCT05933083

RECRUITING NA 320 participants

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Procyrion

NCT05677100

RECRUITING 70 participants

Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status

University of Virginia

NCT06009276

RECRUITING Phase 1 57 participants

Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction

Sardocor

NCT04703842

RECRUITING NA 52 participants

Paced Heart Rate Acceleration for Cardiac Conditioning

Denice Hodgson-Zingman, MD

NCT06332391

RECRUITING NA 25 participants

Evaluating Infrasonic Hemodynography

Scripps Health

NCT04636892

RECRUITING NA 20 participants

Pilot Study Lp299v Supplementation in Chronic Heart Failure

Medical College of Wisconsin

NCT05752760

ACTIVE NOT RECRUITING Phase 1 39 participants

Clinical Trial of Human Allogenic Culture-expanded Bone Marrow-derived Mesenchymal Stem Cells

BioCardia

NCT05925608

ACTIVE NOT RECRUITING Early Phase 1 32 participants

Mechanistic Studies of Nicotinamide Riboside in Human Heart Failure

University of Washington

NCT04528004

ACTIVE NOT RECRUITING Phase 1 17 participants

AB-1002 in Patients With Class III Heart Failure

AskBio

NCT04179643

COMPLETED NA 2,358 participants

Hemodynamic-GUIDEd Management of Heart Failure

Abbott Medical Devices

NCT03387813

COMPLETED NA 94 participants

Virtual Visits to Optimize Research Trial Offerings to HF Patients

The Cleveland Clinic

NCT04064541

COMPLETED 18 participants

SGLT2 Inhibition in Diabetes and Heart Failure

Virginia Commonwealth University

NCT02862067

Phase Distribution

PhaseTrial count
Phase 1 4

Named interventions

Most-linked intervention names on Heart Failure, Systolic records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Assessment of cardiorespiratory fitness Other
1 trials
CardioMEMS™ HF System Device
1 trials
Virtual Visit Other
1 trials
3 x 10e13vg AB-1002 Biological
1 trials
Diagnostic Catheterization Diagnostic test
1 trials
CardiALLO™ Human Allogenic Culture-expanded Bone marrow-derived Mesenchymal Stem Cells (hMSCs) Combination
1 trials
SRD-001 Biological
1 trials
MindMics earbud Other
1 trials

US sites by state

Facility locations filed on Heart Failure, Systolic trials. A trial with sites in several states counts in each.

California 6 trials
Ohio 3 trials
Wisconsin 2 trials
Washington 2 trials
Virginia 2 trials
Minnesota 2 trials
Maryland 2 trials
Florida 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Heart Failure, Systolic page

14 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 8 Heart Failure, Systolic trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Sardocor sponsors the most Heart Failure, Systolic trials on record, review their full trial history before evaluating a specific study. See Sardocor's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Heart Failure, Systolic condition card totals 14 registered trials; most-linked intervention Assessment of cardiorespiratory fitness; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.