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ClinicalTrials.gov 3 recruiting now full pipeline small index

Heart Defects, Congenital: full-pipeline trial registry

3 of 10 indexed Heart Defects, Congenital trials are currently recruiting.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 3 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Heart Defects, Congenital: 10 US clinical trials tracked, 3 recruiting.

Heart Defects, Congenital is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is National Heart, Lung, and Blood Institute (NHLBI), running 2 of these trials.

Enrollment posture brief

Registry condition heart-defects-congenital

OPEN 3 | RECR 30% | LATE 1 | EARLY 1 | RANK #1724 | SPON 2

Nearest open-share peer: Adrenocortical Carcinoma (30% recruiting · 10 trials)

Acute Leukemia of Ambiguous 80%Achondroplasia40%Heart Defects, Congenita (th…30%Accelerated Phase Chronic My20%Accidental Fall20%
Open-enrollment share among volume-matched conditions near Heart Defects, Congenital

Heart Defects, Congenital lists 3 open slots (30% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Heart Defects, Congenital on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Heart Defects, Congenital is recruiting below its size-band peers.

    3 of 10 indexed trials (30%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Heart Defects, Congenital research.

    National Heart, Lung, and Blood Institute (NHLBI) accounts for 2 of 10 trials (20%). 8 distinct sponsors appear on at least one study for this condition label.

  3. Typical Heart Defects, Congenital enrolment sits around 120 participants.

    Median target enrolment is 120 among the 10 trials that report a genuine target (sentinel values excluded). 5 of those (50%) plan for fewer than 100 participants.

  4. Heart Defects, Congenital research is mostly interventional.

    9 interventional and 1 observational studies make up this index (90% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21Phase 31

Open and recent trials

10 total, page 1 of 1

RECRUITING NA 144 participants

Congenital Heart Disease Physical Activity Lifestyle Study V.2

Jamie Jackson

NCT06003023

RECRUITING NA 50 participants

HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis

Children's Hospital Medical Center, Cincinnati

NCT06175104

RECRUITING Phase 2 24 participants

Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

Nationwide Children's Hospital

NCT04467671

ACTIVE NOT RECRUITING NA 250 participants

Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD

atHeart Medical

NCT04591392

ACTIVE NOT RECRUITING NA 15 participants

Evaluation of the GORE PV1 Device in Patients With Pulmonary Valve Dysfunction

W.L.Gore & Associates

NCT03441971

COMPLETED 1,610 participants

Genetic and Nutritional Causes of Heart Birth Defects

National Heart, Lung, and Blood Institute (NHLBI)

NCT00368732

COMPLETED NA 989 participants

SPECS: Safe Pediatric Euglycemia in Cardiac Surgery

Boston Children's Hospital

NCT00443599

COMPLETED Phase 3 120 participants

Comparison of Hematocrit Levels in Infant Heart Surgery

National Heart, Lung, and Blood Institute (NHLBI)

NCT00006183

COMPLETED NA 39 participants

Tuning in to Kids: An Online, Group Program Tailored for Parents of Children With Congenital Heart Disease

Children's Hospital Medical Center, Cincinnati

NCT06609707

COMPLETED NA 35 participants

Parent Communication for Feeding an Infant With a Heart Defect

University of Wisconsin, Madison

NCT04452201

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 1

Named interventions

Most-linked intervention names on Heart Defects, Congenital records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Guided Participation Behavioral
1 trials
Tuning in to Kids Behavioral
1 trials
Thoracic Surgery Procedure
1 trials
Cardiopulmonary Bypass with Two Different Intra-Operative Hematocrits Procedure
1 trials
Gore PV1 Device
1 trials
reSept ASD Occluder Device
1 trials
Physical Activity Lifestyle Intervention Informed by the Theory of Planned Behavior Behavioral
1 trials
Healthy Lifestyle Education Behavioral
1 trials

US sites by state

Facility locations filed on Heart Defects, Congenital trials. A trial with sites in several states counts in each.

Ohio 6 trials
Massachusetts 4 trials
California 3 trials
Michigan 2 trials
Illinois 2 trials
Wisconsin 1 trials
Texas 1 trials
South Carolina 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Heart Defects, Congenital page

10 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Heart Defects, Congenital condition card totals 10 registered trials; most-linked intervention Guided Participation; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.