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NCT06175104 · ClinicalTrials.gov registry record · NA

HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis

A NA study of Neurodevelopmental Disorders and Depression, Postpartum, sponsored by Children's Hospital Medical Center, Cincinnati.

Recruiting
Registry status
NA
Development phase
50
Enrollment target
4
Study locations

NCT06175104 is a NA study of Neurodevelopmental Disorders and Depression, Postpartum that is actively recruiting participants, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 50 participants, below the 579-participant average among 27 other Neurodevelopmental Disorders trials with a reported enrollment target (91% lower). The trial reports 4 study locations across 3 states.

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The verdict

NCT06175104, a NA study of Neurodevelopmental Disorders and Depression, Postpartum, is actively recruiting participants, sponsored by Children's Hospital Medical Center, Cincinnati.

RECRUITING
Registry status
NA
Development phase
50 participants
Enrollment target
4
Study locations

Study Summary

Babies with single ventricle congenital heart disease (SVCHD) are often diagnosed during pregnancy. While prenatal diagnosis has important clinical benefits, it is often stressful and overwhelming for parents, and many express a need for psychological support. HeartGPS is a psychological intervention for parents who receive their baby's diagnosis of SVCHD during pregnancy. It includes 8 sessions with a psychologist, coupled with tailored educational resources, and a personalized care plan. The intervention focuses on fostering parent psychological adjustment and wellbeing, and supporting parents to bond with their baby in ways that feel right for them. Through this study, the investigators will learn if HeartGPS is useful and effective for parents and their babies when it is offered in addition to usual fetal cardiac care. The investigators will examine the effects of the HeartGPS intervention on parental anxiety, depression, and traumatic stress; fetal and infant brain development; parent-infant bonding; and infant neurobehavioral and neurodevelopmental outcomes. The investigators will also explore mechanisms associated with stress biology during pregnancy, infant brain development and neurodevelopmental outcomes, and parent and infant intervention effects.

Interventions

  • BEHAVIORAL HeartGPS

Study Locations (4)

New South Wales

  • Sydney Children's Hospital - Randwick
  • The Children's Hospital at Westmead - Westmead

California

  • Children's Hospital Los Angeles - Los Angeles

Ohio

  • Children's Hospital Medical Center, Cincinnati - Cincinnati

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2025-07-14
Est. Completion 2027-12
Phase NA

What the Registry Record Tells You About NCT06175104

The ClinicalTrials.gov registry entry for NCT06175104 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 579-participant average among 27 other Neurodevelopmental Disorders trials with a reported enrollment target (91% lower). The listed sponsor is Children's Hospital Medical Center, Cincinnati, which has 571 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Neurodevelopmental Disorders appearing as the primary indexed condition, and to 1 intervention - of which HeartGPS is the first listed.

NCT06175104 reports 4 study locations spanning 3 distinct geographic areas - top geographies include New South Wales, California, Ohio.

Frequently Asked Questions

What is clinical trial NCT06175104 about?

NCT06175104 is a clinical study titled "HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis". Babies with single ventricle congenital heart disease (SVCHD) are often diagnosed during pregnancy. While prenatal diagnosis has important clinical benefits, it is often stressful and overwhelming for parents, and many express a need for psychological support. HeartGPS is a psychological interventio...

What is the current status of trial NCT06175104?

This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2025-07-14. Estimated completion is 2027-12.

What conditions does trial NCT06175104 study?

This clinical trial studies the following conditions: Neurodevelopmental Disorders, Depression, Postpartum, Trauma, Psychological, Heart Defects, Congenital, Anxiety in Pregnancy.

What interventions are being tested in trial NCT06175104?

The interventions under investigation include: HeartGPS (BEHAVIORAL).

Who is sponsoring clinical trial NCT06175104?

This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06175104 being conducted?

This trial has 4 study locations across California, Ohio, New South Wales. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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