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NCT05498103 · ClinicalTrials.gov registry record · Phase 4

Use of Methazolamide to Lower Intraocular Pressure

A Phase 4 study of Glaucoma Open-Angle, sponsored by University of Colorado, Denver.

Active
Registry status
Phase 4
Development phase
30
Enrollment target
1
Study location

NCT05498103: Active Phase 4 study of Glaucoma Open-Angle, sponsored by University of Colorado, Denver.

NCT05498103 is a Phase 4 study of Glaucoma Open-Angle that is active but no longer recruiting, run by University of Colorado, Denver. The registered enrollment target is 30 participants, below the 164-participant average among 22 other Glaucoma Open-Angle trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05498103, a Phase 4 study of Glaucoma Open-Angle, is active but no longer recruiting, sponsored by University of Colorado, Denver.

ACTIVE NOT RECRUITING
Registry status
Phase 4
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate the effect of methazolamide, 25 mg or 50 mg tablets once a day for a week than twice a day for a week, on lowering intraocular pressure and the safety of methazolamide.

Primary Outcome

IOP measure is measured using Goldmann Tonometry. IOP is measured in mmHg with a normal range from 12 mmHg to 22 mmHg.

Conditions Studied

Interventions

  • DRUG Methazolamide 25 MG
  • DRUG Methazolamide 50 MG

Study Locations (1)

Colorado

  • Sue Anschutz-Rodgers Eye Center - Aurora

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2023-02-17
Est. Completion 2024-12
Phase Phase 4
University of Colorado, Denver

1,283 total trials

What the registry record for NCT05498103 still lists

NCT05498103 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 164-participant average among 22 other Glaucoma Open-Angle trials with a reported enrollment target (82% lower).

The record links to 1 condition, with Glaucoma Open-Angle appearing as the primary indexed condition, and to 2 interventions - of which Methazolamide 25 MG is the first listed.

NCT05498103 reports a single indexed study location in Colorado.

Frequently Asked Questions

What is clinical trial NCT05498103 about?

NCT05498103 is a clinical study titled "Use of Methazolamide to Lower Intraocular Pressure". The purpose of this study is to evaluate the effect of methazolamide, 25 mg or 50 mg tablets once a day for a week than twice a day for a week, on lowering intraocular pressure and the safety of methazolamide.

What is the current status of trial NCT05498103?

This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2023-02-17. Estimated completion is 2024-12.

What conditions does trial NCT05498103 study?

This clinical trial studies the following conditions: Glaucoma Open-Angle.

What interventions are being tested in trial NCT05498103?

The interventions under investigation include: Methazolamide 25 MG (DRUG), Methazolamide 50 MG (DRUG).

Who is sponsoring clinical trial NCT05498103?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05498103 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Glaucoma Open-Angle

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05498103's enrollment target sits among peer trials

30 21st of 22 higher than 1 of 22 other Glaucoma Open-Angle trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Glaucoma Open-Angle trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05498103, the US trial registry maintained by the National Library of Medicine. NCT05498103 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.