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COMPLETED Phase 3

Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular Hypertension

NCT02247804 · View on ClinicalTrials.gov ↗

Study Summary

This study will evaluate the efficacy and safety of bimatoprost SR in participants with open-angle glaucoma or ocular hypertension. The study includes a 12-month treatment period with an 8-month extended follow-up.

Interventions

  • DRUG Bimatoprost SR
  • DRUG Active Comparator: Timolol 0.5%
  • OTHER Sham: Applicator Without Needle
  • DRUG Timolol Vehicle (placebo)

Study Locations (20)

California

  • Lugene Eye Institute — Glendale
  • Lakeside Vision Center — Irvine
  • Hamilton Glaucoma Center, Shiley Eye Center UCSD — La Jolla
  • Atlantis Eye Care — Long Beach
  • Glaucoma Institute of Beverly Hills — Los Angeles
  • Montebello Medical Eye Center Inc. — Montebello
  • Stanford University — Palo Alto
  • Foothill Eye Institute — Pasadena
  • Martel Eye Medical Group — Rancho Cordova
  • Grutzmacher, Lewis and Sierra, Inc. — Sacramento
  • Pacific Eye Associates — San Francisco

Florida

  • Palm Beach Eye Center, INC — Atlantis
  • Nature Coast Clinical Research — Crystal River
  • Levenson Eye Associates — Jacksonville
  • East Florida Eye Institute — Stuart
  • International Research Center — Tampa

Arizona

  • Arizona Glaucoma Specialists — Phoenix

Colorado

  • Eye Associates of Colorado Springs — Colorado Springs

Georgia

  • Coastal Research Associates, LLC — Roswell

Illinois

  • Chicago Eye Specialists — Chicago

Trial Details

FieldValue
Enrollment Target 594 participants
Start Date 2014-12-15
Est. Completion 2019-07-19
Phase Phase 3

Sponsor

Allergan

52 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02247804

The ClinicalTrials.gov registry entry for NCT02247804 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 594 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Allergan, which has 52 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Ocular Hypertension appearing as the primary indexed condition, and to 4 interventions — of which Bimatoprost SR is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02247804 reports 20 study locations spanning 6 distinct geographic areas — top geographies include California, Florida, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02247804 about?

NCT02247804 is a clinical study titled "Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular Hypertension". This study will evaluate the efficacy and safety of bimatoprost SR in participants with open-angle glaucoma or ocular hypertension. The study includes a 12-month treatment period with an 8-month extended follow-up.

What is the current status of trial NCT02247804?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 594 participants. The study started on 2014-12-15. Estimated completion is 2019-07-19.

What conditions does trial NCT02247804 study?

This clinical trial studies the following conditions: Ocular Hypertension, Glaucoma, Open-Angle. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02247804?

The interventions under investigation include: Bimatoprost SR (DRUG), Active Comparator: Timolol 0.5% (DRUG), Sham: Applicator Without Needle (OTHER), Timolol Vehicle (placebo) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02247804?

This trial is sponsored by Allergan, which has 52 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02247804 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial