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Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms
NCT04661215 · View on ClinicalTrials.gov ↗
Study Summary
The overall objective of this study is to determine if there are pyloric sphincter abnormalities in patients with gastroparesis symptoms and determine how prevalent these abnormalities are using tests to assess the pyloric sphincter - endoluminal functional luminal imaging probe (Endoflip™), water load satiety testing (WLST), and high-resolution cutaneous electrogastrography (HR-EGG) using Gastric Alimetry™ System.
Conditions Studied
Study Locations (6)
Arizona
- Mayo Clinic Arizona — Scottsdale
Kentucky
- University of Louisville — Louisville
Massachusetts
- Massachusetts General — Boston
North Carolina
- Wake Forest University Health Sciences — Winston-Salem
Pennsylvania
- Temple University — Philadelphia
Texas
- Texas Tech University Health Science Center (TTUHSC) — El Paso
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2026-01-13 |
| Est. Completion | 2027-04-15 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04661215
The ClinicalTrials.gov registry entry for NCT04661215 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins Bloomberg School of Public Health, which has 209 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Gastroparesis appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04661215 reports 6 study locations spanning 6 distinct geographic areas — top geographies include Arizona, Kentucky, Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04661215 about?
NCT04661215 is a clinical study titled "Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms". The overall objective of this study is to determine if there are pyloric sphincter abnormalities in patients with gastroparesis symptoms and determine how prevalent these abnormalities are using tests to assess the pyloric sphincter - endoluminal functional luminal imaging probe (Endoflip™), water l...
What is the current status of trial NCT04661215?
This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2026-01-13. Estimated completion is 2027-04-15.
What conditions does trial NCT04661215 study?
This clinical trial studies the following conditions: Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastric Motility Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT04661215?
This trial is sponsored by Johns Hopkins Bloomberg School of Public Health, which has 209 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04661215 being conducted?
This trial has 6 study locations across Arizona, Kentucky, Massachusetts, North Carolina, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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