Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Endometrial Neoplasms

Open-data reference.

15 US clinical trials · 6 currently recruiting

Active & Recent Trials

RECRUITING Phase 1 540 participants

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Eli Lilly and Company

NCT04956640

RECRUITING Phase 1 495 participants

A Study of LY4170156 in Participants With Selected Advanced Solid Tumors

Eli Lilly and Company

NCT06400472

RECRUITING Phase 1 421 participants

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

Eli Lilly and Company

NCT07114601

RECRUITING Phase 1 240 participants

A Study of LY4175408 in Participants With Advanced Cancer

Eli Lilly and Company

NCT07046923

RECRUITING Phase 1 160 participants

A Study of DM002 in Patients With Advanced Solid Tumors

Xadcera Biopharmaceutical (Suzhou) Co.

NCT06751329

RECRUITING Phase 1 150 participants

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NiKang Therapeutics

NCT06586957

ACTIVE NOT RECRUITING Phase 3 990 participants

Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)

Merck Sharp & Dohme

NCT04634877

ACTIVE NOT RECRUITING Phase 3 805 participants

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

AstraZeneca

NCT04269200

ACTIVE NOT RECRUITING Phase 1 301 participants

A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor

Eisai

NCT04008797

ACTIVE NOT RECRUITING Phase 3 280 participants

Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma (MK-3475-C93/KEYNOTE-C93/GOG-3064/ENGOT-en15)

Merck Sharp & Dohme

NCT05173987

ACTIVE NOT RECRUITING Phase 2 120 participants

A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2

Seagen, a wholly owned subsidiary of Pfizer

NCT06003231

ACTIVE NOT RECRUITING Phase 1 120 participants

Evaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid Tumors

SystImmune

NCT06714617

COMPLETED NA 600 participants

Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors

Wake Forest University Health Sciences

NCT03935282

COMPLETED 26 participants

Pre-Clinical Models in Gynecological Tumors A Tissue Repository

University of New Mexi

NCT00250783

COMPLETED NA 17 participants

Time Restricted Eating (TRE) Among Native Hawaiian/Pacific Islander Women at Risk for Endometrial Cancer

University of Utah

NCT04763902

Phase Distribution

PhaseTrial count
Early Phase 1 8
Phase 2 1
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Endometrial Neoplasms Trial Landscape

ClinicalTrials.gov lists 15 US studies indexed under Endometrial Neoplasms, and 6 of those are currently open to recruitment — roughly 40% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Endometrial Neoplasms shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Endometrial Neoplasms is led by Eli Lilly and Company with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 15 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Endometrial Neoplasms?

PlainTrial tracks 15 US clinical trials for Endometrial Neoplasms, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Endometrial Neoplasms?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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