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ClinicalTrials.gov 11 recruiting now official registry

End Stage Liver DIsease clinical trials

11 of 17 indexed End Stage Liver DIsease trials are currently recruiting.

17 US clinical trials · 11 currently recruiting

End Stage Liver DIsease is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is University of Pennsylvania, running 2 of these trials.

The research picture

End Stage Liver DIsease has 17 registered US clinical trials, 11 of them open to new participants right now, about 65% of the total.

11
recruiting participants now
65%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: University of Pennsylvania
Phase 12Phase 22Phase 41

Active & Recent Trials

17 total, page 1 of 1

RECRUITING 5,000 participants

Functional Assessment in Liver Transplantation

University of California, San Francisco

NCT03228290

RECRUITING NA 1,000 participants

Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors

Johns Hopkins University

NCT03803423

RECRUITING NA 360 participants

Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant

University of Pennsylvania

NCT05260268

RECRUITING NA 200 participants

LiverPAL: A Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease

Massachusetts General Hospital

NCT05998330

RECRUITING NA 110 participants

Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease

University of Pennsylvania

NCT06136221

RECRUITING 100 participants

Disparities Among Liver Transplant Patients

Mayo Clinic

NCT05981196

RECRUITING NA 100 participants

Adverse Outcomes and Mortality in Liver Transplant

Mayo Clinic

NCT05477277

RECRUITING NA 30 participants

HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease

Massachusetts General Hospital

NCT05205954

RECRUITING Phase 1 12 participants

Immune Tolerance Induction After Liver Transplantation

University of California, Los Angeles

NCT07269041

RECRUITING Phase 2 12 participants

Allogenic Hepatocyte Transplantation Into Periduodenal Lymph Nodes

LyGenesis

NCT04496479

RECRUITING Phase 1 8 participants

A Study of SIPLIZUMAB in AILD and LT Patients

Elizabeth C. Verna

NCT06455280

ACTIVE NOT RECRUITING Phase 2 70 participants

Tocotrienol Against the Progression of End Stage Liver Disease

Chandan Sen

NCT02581085

COMPLETED Phase 4 312 participants

Study of Liver Transplant For End-Stage Liver Disease Caused By Chronic Hepatitis C Infection

Baylor Research Institute

NCT00163657

COMPLETED NA 219 participants

Bridge to HOPE: Hypothermic Oxygenated Perfusion Versus Cold Storage Prior to Liver Transplantation

Bridge to Life

NCT05045794

COMPLETED 200 participants

Psychosocial Risks in Liver Transplant Recipients

Icahn School of Medicine at Mount Sinai

NCT02826460

COMPLETED NA 97 participants

Surprise Question in End of Life (SeQuEL) Care and the Effect of Prompting Palliative Care Consultation: End-Stage Liver Disease

Vanderbilt University Medical Center

NCT06400498

COMPLETED NA 30 participants

End Stage Liver Disease and Body Composition Assessment: Utilizing Bioelectric Impedance Analysis (BIA)

University of Cincinnati

NCT00374582

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 2
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the End Stage Liver DIsease Trial Landscape

17 indexed End Stage Liver DIsease studies · 11 recruiting (65%).

Phase mix: 1 late (III/IV) vs 4 early (I/II).

Top sponsor: University of Pennsylvania (2 trials), 9 others listed. 17 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for End Stage Liver DIsease?

PlainTrial tracks 17 US clinical trials for End Stage Liver DIsease, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for End Stage Liver DIsease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.