Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02581085 · ClinicalTrials.gov registry record · Phase 2

Tocotrienol Against the Progression of End Stage Liver Disease

A Phase 2 study of NASH - Nonalcoholic Steatohepatitis and End Stage Liver DIsease, sponsored by Chandan Sen.

Active
Registry status
Phase 2
Development phase
70
Enrollment target
1
Study location

NCT02581085 is a Phase 2 study of NASH - Nonalcoholic Steatohepatitis and End Stage Liver DIsease that is active but no longer recruiting, run by Chandan Sen. The registered enrollment target is 70 participants, below the 266-participant average among 27 other NASH - Nonalcoholic Steatohepatitis trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02581085, a Phase 2 study of NASH - Nonalcoholic Steatohepatitis and End Stage Liver DIsease, is active but no longer recruiting, sponsored by Chandan Sen.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
70 participants
Enrollment target
1
Study location

Study Summary

The purpose of this Phase 2 trial is to validate the outcome observed in a previous trial that oral Tocotrienol (TCT) attenuates the rise in MELD score over time in patients with end stage liver disease / cirrhosis. The study is double blind and participants will be randomized to take 2 capsules of TCT (200mg) or placebo twice a day for 3 years.

Conditions Studied

NASH - Nonalcoholic Steatohepatitis End Stage Liver DIsease NAFLD - Nonalcoholic Fatty Liver Disease

Interventions

  • OTHER Placebo
  • DRUG Tocotrienol (TCT)

Study Locations (1)

Indiana

  • IU Health Unviersity Hospital - Indianapolis

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2019-11-01
Est. Completion 2028-12-31
Phase Phase 2

Sponsor

Chandan Sen

2 total trials

Interested in This Trial?

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02581085

The ClinicalTrials.gov registry entry for NCT02581085 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 266-participant average among 27 other NASH - Nonalcoholic Steatohepatitis trials with a reported enrollment target (74% lower). The listed sponsor is Chandan Sen, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with NASH - Nonalcoholic Steatohepatitis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02581085 reports 1 study location spanning 1 distinct geographic area - top geographies include Indiana.

Frequently Asked Questions

What is clinical trial NCT02581085 about?

NCT02581085 is a clinical study titled "Tocotrienol Against the Progression of End Stage Liver Disease". The purpose of this Phase 2 trial is to validate the outcome observed in a previous trial that oral Tocotrienol (TCT) attenuates the rise in MELD score over time in patients with end stage liver disease / cirrhosis. The study is double blind and participants will be randomized to take 2 capsules of ...

What is the current status of trial NCT02581085?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2019-11-01. Estimated completion is 2028-12-31.

What conditions does trial NCT02581085 study?

This clinical trial studies the following conditions: NASH - Nonalcoholic Steatohepatitis, End Stage Liver DIsease, NAFLD - Nonalcoholic Fatty Liver Disease.

What interventions are being tested in trial NCT02581085?

The interventions under investigation include: Placebo (OTHER), Tocotrienol (TCT) (DRUG).

Who is sponsoring clinical trial NCT02581085?

This trial is sponsored by Chandan Sen, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02581085 being conducted?

This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for NASH - Nonalcoholic Steatohepatitis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Explore more on PlainTrial

NASH - Nonalcoholic Steatohepatitis

All registered trials for this condition

End Stage Liver DIsease

All registered trials for this condition

Indiana

All trials with a study site in Indiana

Recruiting now

Find trials open to new participants near you

Rankings

Top sponsors, conditions, and phases

Read our methodology - how this data is sourced, computed, and verified.

Related

Browse all → | Rankings →
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.