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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Depression, Postpartum: early-phase trial registry

5 of 16 indexed Depression, Postpartum trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 5 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Depression, Postpartum: 16 US clinical trials tracked, 5 recruiting.

Depression, Postpartum is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is University of Chicago, running 2 of these trials.

Enrollment posture brief

Registry condition depression-postpartum

OPEN 5 | RECR 31% | LATE 1 | EARLY 4 | RANK #1060 | SPON 2

Nearest open-share peer: Aortic Valve Disease (31% recruiting · 16 trials)

Adolescent62.5%Alcohol Intoxication56.3%AL Amyloidosis43.8%Depression, Postpartum (this)31%Allergy18.8%
Open-enrollment share among volume-matched conditions near Depression, Postpartum

Depression, Postpartum lists 5 open slots (31% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Depression, Postpartum on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Depression, Postpartum is recruiting below its size-band peers.

    5 of 16 indexed trials (31.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Depression, Postpartum trials is spread across many organizations.

    University of Chicago accounts for 2 of 16 trials (12.5%). 15 distinct sponsors appear on at least one study for this condition label.

  3. Typical Depression, Postpartum enrolment sits around 150 participants.

    Median target enrolment is 150 among the 16 trials that report a genuine target (sentinel values excluded). 6 of those (37.5%) plan for fewer than 100 participants.

  4. Depression, Postpartum research is mostly interventional.

    15 interventional and 1 observational studies make up this index (93.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 24Phase 41

Open and recent trials

16 total, page 1 of 1

RECRUITING 200 participants

A Study to Learn More About How Zuranolone Affects Postpartum Depression Symptoms in Participants Who Took it Within 1 Year After The End of Their Pregnancy

Biogen

NCT07047820

RECRUITING NA 156 participants

Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum Depression

University of Pennsylvania

NCT06877104

RECRUITING Phase 2 150 participants

Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

Cedars-Sinai Medical Center

NCT05552053

RECRUITING NA 100 participants

IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression

University of Washington

NCT06746337

RECRUITING NA 50 participants

HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis

Children's Hospital Medical Center, Cincinnati

NCT06175104

ACTIVE NOT RECRUITING NA 20 participants

Enhancing Mental and Physical Health of Women Veterans

VA Office of Research and Development

NCT05050266

COMPLETED NA 590 participants

Using a Preparation and Education Intervention to Reduce Postpartum Depression Among New Mothers (The MADE IT 2 Study)

Icahn School of Medicine at Mount Sinai

NCT00951717

COMPLETED NA 248 participants

Doula Support for Young Mothers: A Randomized Trial

University of Chicago

NCT01925664

COMPLETED Phase 4 238 participants

Effectiveness of Supplemental Calcium in Preventing Postpartum Depression

Oregon Health and Science University

NCT00228033

COMPLETED NA 177 participants

Madres Para la Salud (Mothers for Health)

Arizona State University

NCT01908959

COMPLETED Phase 2 162 participants

Effectiveness of Sertraline Alone and Interpersonal Psychotherapy Alone in Treating Women With Postpartum Depression

Women and Infants Hospital of Rhode Island

NCT00602355

COMPLETED Phase 2 109 participants

Inhaled Oxytocin and HPA Axis Reactivity

University of North Carolina, Chapel Hill

NCT03593473

COMPLETED Phase 2 93 participants

A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression

DuKang Pharmaceuticals

NCT06285916

COMPLETED NA 70 participants

Meditation for NICU Moms

St. Louis University

NCT03574766

COMPLETED NA 61 participants

CSE v. Epidural for Postpartum Depression

Grace Lim, MD, MS

NCT03022526

COMPLETED NA 31 participants

Tracking Depression Symptoms With a Health Chatbot

University of Chicago

NCT03990389

Phase Distribution

PhaseTrial count
Phase 2 4
Phase 4 1

Named interventions

Most-linked intervention names on Depression, Postpartum records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
3 trials
Mothercrafting Behavioral
1 trials
Clinical management Behavioral
1 trials
Interpersonal psychotherapy (IPT) Behavioral
1 trials
NORA520 Dose 2 Drug
1 trials
NORA520 Dose 1 Drug
1 trials
Behavioral education intervention Behavioral
1 trials
Madres para la Salud Behavioral
1 trials

US sites by state

Facility locations filed on Depression, Postpartum trials. A trial with sites in several states counts in each.

California 4 trials
Illinois 3 trials
Rhode Island 2 trials
Pennsylvania 2 trials
New York 2 trials
North Carolina 2 trials
Washington 1 trials
Texas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Depression, Postpartum page

16 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Depression, Postpartum condition card totals 16 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.