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Depression, Postpartum
Open-data reference.
16 US clinical trials · 5 currently recruiting
Active & Recent Trials
A Study to Learn More About How Zuranolone Affects Postpartum Depression Symptoms in Participants Who Took it Within 1 Year After The End of Their Pregnancy
Biogen
NCT07047820
Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum Depression
University of Pennsylvania
NCT06877104
Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women
Cedars-Sinai Medical Center
NCT05552053
IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression
University of Washington
NCT06746337
HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis
Children's Hospital Medical Center, Cincinnati
NCT06175104
Enhancing Mental and Physical Health of Women Veterans
VA Office of Research and Development
NCT05050266
Using a Preparation and Education Intervention to Reduce Postpartum Depression Among New Mothers (The MADE IT 2 Study)
Icahn School of Medicine at Mount Sinai
NCT00951717
Doula Support for Young Mothers: A Randomized Trial
University of Chicago
NCT01925664
Effectiveness of Supplemental Calcium in Preventing Postpartum Depression
Oregon Health and Science University
NCT00228033
Madres Para la Salud (Mothers for Health)
Arizona State University
NCT01908959
Effectiveness of Sertraline Alone and Interpersonal Psychotherapy Alone in Treating Women With Postpartum Depression
Women and Infants Hospital of Rhode Island
NCT00602355
Inhaled Oxytocin and HPA Axis Reactivity
University of North Carolina, Chapel Hill
NCT03593473
A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression
DuKang Pharmaceuticals
NCT06285916
Meditation for NICU Moms
St. Louis University
NCT03574766
CSE v. Epidural for Postpartum Depression
Grace Lim, MD, MS
NCT03022526
Tracking Depression Symptoms With a Health Chatbot
University of Chicago
NCT03990389
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 4 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Depression, Postpartum Trial Landscape
ClinicalTrials.gov lists 16 US studies indexed under Depression, Postpartum, and 5 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Depression, Postpartum shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Depression, Postpartum is led by University of Chicago with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Depression, Postpartum?
PlainTrial tracks 16 US clinical trials for Depression, Postpartum, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Depression, Postpartum?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.