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NCT02702102 · ClinicalTrials.gov registry record · Phase 2

Imaging Inflammation in Patients With Parkinson's Disease Dementia or Dementia With Lewy Bodies

A Phase 2 study of Dementia With Lewy Bodies and Diffuse Lewy Body Disease, sponsored by Columbia University.

Completed
Registry status
Phase 2
Development phase
5
Enrollment target
1
Study location

NCT02702102: Completed Phase 2 study of Dementia With Lewy Bodies and Diffuse Lewy Body Disease, sponsored by Columbia University.

NCT02702102 is a Phase 2 study of Dementia With Lewy Bodies and Diffuse Lewy Body Disease that has completed, run by Columbia University. The registered enrollment target is 5 participants, below the 471-participant average among 22 other Dementia With Lewy Bodies trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02702102, a Phase 2 study of Dementia With Lewy Bodies and Diffuse Lewy Body Disease, has completed, sponsored by Columbia University.

COMPLETED
Registry status
Phase 2
Development phase
5 participants
Enrollment target
1
Study location

Study Summary

This study uses a special type of scan called a positron emission tomography (PET) scan to take pictures of the brain. During the PET scan, a special dye called 11C-PBR28 is injected into the body. 11C-PBR28 sticks to parts of the brain where there is inflammation. The purpose of this study is to see if 11C-PBR28 can detect inflammation in patients with Parkinson's disease dementia or dementia with Lewy bodies. 11C-PBR28 is considered a drug by the Food and Drug Administration. 11C-PBR28 is not a treatment for any disease. Rather, 11C-PBR28 can be used to measure inflammation in the brain.

Primary Outcome

Using Arterial blood sampling and 11C-PBR28 PET scan uptake, a Vt was found (as opposed to an SUVR) for target regions. Volume of distribution (VT) of a radioligand is defined as the ratio of the radioligand concentration in tissue target region (CT, kBq·cm-3) to that in plasma (CP, kBq·mL-1) at equilibrium.

Conditions Studied

Dementia With Lewy Bodies Diffuse Lewy Body Disease Parkinson's Disease Dementia

Interventions

  • DRUG 11C-PBR28

Study Locations (1)

New York

  • Columbia University Medical Center - New York

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2015-12
Est. Completion 2019-09-04
Phase Phase 2
Columbia University

958 total trials

What the finished NCT02702102 record still lists

NCT02702102 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 471-participant average among 22 other Dementia With Lewy Bodies trials with a reported enrollment target (99% lower).

The record links to 3 conditions, with Dementia With Lewy Bodies appearing as the primary indexed condition, and to 1 intervention - of which 11C-PBR28 is the first listed.

NCT02702102 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT02702102 about?

NCT02702102 is a clinical study titled "Imaging Inflammation in Patients With Parkinson's Disease Dementia or Dementia With Lewy Bodies". This study uses a special type of scan called a positron emission tomography (PET) scan to take pictures of the brain. During the PET scan, a special dye called 11C-PBR28 is injected into the body. 11C-PBR28 sticks to parts of the brain where there is inflammation. The purpose of this study is to s...

What is the current status of trial NCT02702102?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 5 participants. The study started on 2015-12. Estimated completion is 2019-09-04.

What conditions does trial NCT02702102 study?

This clinical trial studies the following conditions: Dementia With Lewy Bodies, Diffuse Lewy Body Disease, Parkinson's Disease Dementia.

What interventions are being tested in trial NCT02702102?

The interventions under investigation include: 11C-PBR28 (DRUG).

Who is sponsoring clinical trial NCT02702102?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02702102 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Dementia With Lewy Bodies

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02702102's enrollment target sits among peer trials

5 23rd of 22 the lowest of 22 other Dementia With Lewy Bodies trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Dementia With Lewy Bodies trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT02702102, the US trial registry maintained by the National Library of Medicine. NCT02702102 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.