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NCT03924414 · ClinicalTrials.gov registry record · Phase 4

Trial of Parkinson's And Zoledronic Acid

A Phase 4 study of Parkinson Disease and Osteoporosis, sponsored by California Pacific Medical Center Research Institute.

Active
Registry status
Phase 4
Development phase
2,650
Enrollment target
20
Study locations

NCT03924414 is a Phase 4 study of Parkinson Disease and Osteoporosis that is active but no longer recruiting, run by California Pacific Medical Center Research Institute. The registered enrollment target is 2,650 participants, below the 5,317-participant average among 297 other Parkinson Disease trials with a reported enrollment target (50% lower). The trial reports 20 study locations across 5 states.

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The verdict

NCT03924414, a Phase 4 study of Parkinson Disease and Osteoporosis, is active but no longer recruiting, sponsored by California Pacific Medical Center Research Institute.

ACTIVE NOT RECRUITING
Registry status
Phase 4
Development phase
2,650 participants
Enrollment target
20
Study locations

Study Summary

This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 2650 participants will be enrolled and randomized in the United States. Participants, follow-up outcome assessors, and study investigators will be blinded to assigned study treatment. This trial is funded by the National Institute of Aging.

Conditions Studied

Parkinson Disease Osteoporosis Multiple System Atrophy Dementia With Lewy Bodies Progressive Supranuclear Palsy Parkinson's Disease and Parkinsonism Parkinsonism Vascular Parkinsonism Atypical Parkinsonism

Interventions

  • OTHER Placebo
  • DRUG Zoledronic Acid 5Mg/Bag 100Ml Inj

Study Locations (20)

California

  • Sutter Health - Berkeley
  • Parkinson's and Movement Disorder Institute - Fountain Valley
  • University of California, Irvine - Irvine
  • Loma Linda University - Loma Linda
  • Cedars-Sinai Medical Center - Los Angeles
  • University of California, Los Angeles - Los Angeles
  • Valley Parkinson Clinic - Los Gatos
  • Parkinson's Disease and Movement Disorder Center of Silicon Valley - Palo Alto
  • University of California, Riverside - Riverside
  • Sutter Health - Sacramento
  • University of California, Davis - Sacramento
  • University of California, San Francisco - San Francisco

Connecticut

  • University of Connecticut - Farmington
  • University of Connecticut - Farmington
  • Hartford Healthcare - Hartford

Arkansas

  • Washington Regional Medical Center - Fayetteville
  • University of Arkansas for Medical Sciences - Little Rock

Colorado

  • University of Colorado, Denver - Aurora
  • St. Mary's Medical Center - Grand Junction

Arizona

  • Mayo Clinic - Scottsdale

Trial Details

FieldValue
Enrollment Target 2,650 participants
Start Date 2019-11-15
Est. Completion 2025-10-31
Phase Phase 4

Sponsor

California Pacific Medical Center Research Institute

29 total trials

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What the Registry Record Tells You About NCT03924414

The ClinicalTrials.gov registry entry for NCT03924414 describes a study currently listed as active not recruiting, categorized as Phase 4. The registered enrollment target is 2,650 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,317-participant average among 297 other Parkinson Disease trials with a reported enrollment target (50% lower). The listed sponsor is California Pacific Medical Center Research Institute, which has 29 total studies on file at ClinicalTrials.gov.

The record links to 9 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT03924414 reports 20 study locations spanning 5 distinct geographic areas - top geographies include California, Connecticut, Arkansas.

Frequently Asked Questions

What is clinical trial NCT03924414 about?

NCT03924414 is a clinical study titled "Trial of Parkinson's And Zoledronic Acid". This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 2650 participants w...

What is the current status of trial NCT03924414?

This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 2,650 participants. The study started on 2019-11-15. Estimated completion is 2025-10-31.

What conditions does trial NCT03924414 study?

This clinical trial studies the following conditions: Parkinson Disease, Osteoporosis, Multiple System Atrophy, Dementia With Lewy Bodies, Progressive Supranuclear Palsy.

What interventions are being tested in trial NCT03924414?

The interventions under investigation include: Placebo (OTHER), Zoledronic Acid 5Mg/Bag 100Ml Inj (DRUG).

Who is sponsoring clinical trial NCT03924414?

This trial is sponsored by California Pacific Medical Center Research Institute, which has 29 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03924414 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.